| RS758477536 |
MMACHC
|
Health Risk |
Pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS758478717 |
NPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature with nonspecific skeletal abnormalities, Acromesomelic dysplasia 1 |
| RS758478864 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758480654 |
IL10RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inflammatory bowel disease 28, Familial cancer of breast |
| RS758482171 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS758482424 |
CCDC39
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758482449 |
PCDH15
|
Health Risk |
Likely pathogenic |
Usher syndrome type 1F, Usher syndrome type 1F |
| RS758482493 |
ARSG
|
Health Risk |
Pathogenic |
— |
| RS758483877 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758484631 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758485261 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS758486336 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS758486944 |
DARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome, Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome |
| RS758487568 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS758487727 |
COL7A1
|
Health Risk |
Pathogenic |
— |
| RS758487789 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS758487924 |
SEC63
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic liver disease 2, Biliary tract abnormality |
| RS75848804 |
FGG
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 4, Congenital afibrinogenemia |
| RS758488919 |
GSDME
|
Health Risk |
Conflicting classifications of pathogenicity |
Nonsyndromic genetic hearing loss, GSDME-related disorder |
| RS758489218 |
OTOG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758490440 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS758491296 |
CYP24A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hypercalcemia |
| RS758491525 |
TAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Tyrosinemia type II, Tyrosinemia type II |
| RS758493174 |
CCDC39
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 14 |
| RS758493460 |
AGXT
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary hyperoxaluria, type I |
| RS758493823 |
LRP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cenani-Lenz syndactyly syndrome, Congenital myasthenic syndrome 17 |
| RS758494245 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease 2, Pulmonary fibrosis and/or bone marrow failure |
| RS758494304 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS758494581 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758494772 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Inborn genetic diseases |
| RS758495626 |
SELENBP1
|
Health Risk |
Likely pathogenic |
Extra oral halitosis, Extraoral halitosis due to methanethiol oxidase deficiency |
| RS758495950 |
GCK
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinism due to glucokinase deficiency, Maturity-onset diabetes of the young type 2 |
| RS758496577 |
DEAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758497476 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS758498215 |
GRM6
|
Health Risk |
Likely pathogenic |
— |
| RS758498345 |
FANCM
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, FANCM-related disorder |
| RS758498695 |
NPHP3
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS758498850 |
BRAF
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS758499040 |
PPP1R13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758499439 |
XRCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS758500749 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS758500897 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonus, intractable |
| RS758502850 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS758503371 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS758503440 |
NPC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C2 |
| RS758503693 |
DGUOK
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758504284 |
NFIX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758504480 |
GBE1
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type IV |
| RS758505358 |
TGM5
|
Health Risk |
Pathogenic |
— |
| RS758505511 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758505618 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS758506007 |
KLHL15
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758506159 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 7, Familial episodic pain syndrome with predominantly lower limb involvement |
| RS758506791 |
MCCC2
|
Health Risk |
Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, Methylcrotonyl-CoA carboxylase deficiency |
| RS758506896 |
EPS8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758506938 |
EYS
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS758507327 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Otospondylomegaepiphyseal dysplasia, autosomal recessive |
| RS758508750 |
DVL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Robinow syndrome 2, Inborn genetic diseases |
| RS758509148 |
ETFB
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Glutaric acidemia IIc |
| RS758509542 |
APOA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS758511419 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis syndrome, Tuberous sclerosis 2 |
| RS758512747 |
MYOT
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 3, Myofibrillar myopathy 3 |
| RS758513686 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS758513858 |
NDUFAF5
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 16 |
| RS758514260 |
TMC6
|
Health Risk |
Pathogenic |
Epidermodysplasia verruciformis, Epidermodysplasia verruciformis |
| RS758515608 |
F11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary factor XI deficiency disease, F11-related disorder |
| RS758516007 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1G |
| RS758517117 |
SMARCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS758517215 |
PHGDH
|
Health Risk |
Likely pathogenic |
PHGDH deficiency, PHGDH deficiency |
| RS758518373 |
NDUFS7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Mitochondrial complex I deficiency |
| RS758520331 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS758521897 |
COG1
|
Health Risk |
Pathogenic |
COG1 congenital disorder of glycosylation, COG1 congenital disorder of glycosylation |
| RS758521939 |
GRIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant |
| RS758521946 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS758522459 |
COQ4
|
Health Risk |
Pathogenic |
Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome, Inborn genetic diseases |
| RS758522600 |
BBS10
|
Health Risk |
Pathogenic |
Asphyxiating thoracic dystrophy 3, Bardet-Biedl syndrome 10 |
| RS758523519 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Inborn genetic diseases |
| RS758523839 |
MARS1
|
Health Risk |
Likely pathogenic |
Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency, Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency |
| RS758524310 |
MED25
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Congenital cataract-microcephaly-nevus flammeus simplex-severe intellectual disability syndrome |
| RS758524873 |
CNGB1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 45, Retinitis pigmentosa 45 |
| RS758524907 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS75852730 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
GLUT1 deficiency syndrome 1, autosomal recessive |
| RS758528026 |
SDHC
|
Health Risk |
Pathogenic |
Pheochromocytoma/paraganglioma syndrome 3, Pheochromocytoma/paraganglioma syndrome 3 |
| RS758528624 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS758529293 |
TMX2
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS758531526 |
AUTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758533436 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758534800 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, Cardiovascular phenotype |
| RS758536777 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758537157 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS758539045 |
CNNM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Jalili syndrome, Jalili syndrome |
| RS758539309 |
COQ8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758539671 |
DMXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute myeloid leukemia, Acute myeloid leukemia |
| RS758539676 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS758539727 |
NKX2-5
|
Health Risk |
Pathogenic |
Atrial septal defect 7, Atrial septal defect 7 |
| RS758539748 |
MRPS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation deficiency 36, Combined oxidative phosphorylation deficiency 36 |
| RS758541435 |
TTI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe intellectual disability-short stature-behavioral abnormalities-facial dysmorphism syndrome, Severe intellectual disability-short stature-behavioral abnormalities-facial dysmorphism syndrome |
| RS758542203 |
GFI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutropenia, severe congenital |
| RS758542279 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS758542643 |
RPGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |