MYLK3 Chromosome 16
Myosin light chain kinase 3
Upload your DNA to see your personal genotypes for variants in MYLK3.
What This Gene Does
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]
Gene Info
Gene Group
Myosin light chain kinase family
Locus Type
gene with protein product
Location
16q11.2
Ensembl
ENSG00000140795
Key Variants
RS113145242
Conflicting classifications of pathogenicity
Health Risk
RS140405555
Conflicting classifications of pathogenicity
Health Risk
RS144566580
Conflicting classifications of pathogenicity
Health Risk
RS151009173
Conflicting classifications of pathogenicity
Health Risk
RS1966904003
Conflicting classifications of pathogenicity
Health Risk
RS200317443
Conflicting classifications of pathogenicity
Health Risk
RS200577835
Conflicting classifications of pathogenicity
Health Risk
RS200653944
Conflicting classifications of pathogenicity
Health Risk
RS374127974
Conflicting classifications of pathogenicity
Health Risk
RS376036303
Conflicting classifications of pathogenicity
Health Risk
RS376487384
Conflicting classifications of pathogenicity
Health Risk
RS544503447
Conflicting classifications of pathogenicity
Health Risk
All Variants (25)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS113145242 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS140405555 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS144566580 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS151009173 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1966904003 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200317443 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200577835 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200653944 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS374127974 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS376036303 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS376487384 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS544503447 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS558671219 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS575256657 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS745833581 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS748998633 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS758287896 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS760783642 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS761650400 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS767498123 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS772851638 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS778647098 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS779509518 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS780172365 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS765089938 | Health Risk | Likely pathogenic | — |