PRDM1 Chromosome 6
PR/SET domain 1
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What This Gene Does
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Zinc fingers C2H2-type|PR/SET domain family|Putative lysine methyltransferases"
Locus Type
gene with protein product
Location
6q21
Ensembl
ENSG00000057657
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS75859409 | Health Risk | Conflicting classifications of pathogenicity | — |