| RS757424322 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS757424379 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS757425728 |
SPTB
|
Health Risk |
Pathogenic/Likely pathogenic |
Elliptocytosis 3, Hereditary spherocytosis type 2 |
| RS757426469 |
NDUFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757427533 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Papillary renal cell carcinoma type 1 |
| RS757428273 |
PCARE
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS757428388 |
ADCY10
|
Health Risk |
Pathogenic |
— |
| RS757428415 |
PIEZO1
|
Health Risk |
Pathogenic |
— |
| RS757428597 |
CBS
|
Health Risk |
Pathogenic/Likely pathogenic |
Classic homocystinuria, Homocystinuria |
| RS757429317 |
TTC8
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 51, Retinitis pigmentosa 51 |
| RS757430199 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniopharyngioma, Gorlin syndrome |
| RS757430423 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS757430776 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS757431407 |
MOCS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, MOCS1-related disorder |
| RS757432625 |
AUTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757433005 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS757434449 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS757434857 |
ACADM
|
Health Risk |
Pathogenic/Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, ACADM-related disorder |
| RS757435241 |
LAMA2
|
Health Risk |
Likely pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS757439328 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS757439664 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 39, Usher syndrome type 2A |
| RS757440752 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS757441073 |
PIGO
|
Health Risk |
Likely pathogenic |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS757441871 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS757442072 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS757442230 |
SLC10A1
|
Health Risk |
Likely pathogenic |
SLC10A1-related disorder, SLC10A1-related disorder |
| RS757442319 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS757444247 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS757444887 |
KCNK4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757446033 |
HERC1
|
Health Risk |
Pathogenic |
Macrocephaly, dysmorphic facies |
| RS757446463 |
SELENON
|
Health Risk |
Conflicting classifications of pathogenicity |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS757448865 |
CAPN3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS757449019 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS757449082 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Ehlers-Danlos syndrome |
| RS757449294 |
ARL2BP
|
Health Risk |
Pathogenic |
— |
| RS757449444 |
WDPCP
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Inborn genetic diseases |
| RS757451467 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Primary dilated cardiomyopathy |
| RS757451824 |
CPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital hyperammonemia, type I |
| RS757452204 |
COG5
|
Health Risk |
Conflicting classifications of pathogenicity |
COG5-congenital disorder of glycosylation, COG5-congenital disorder of glycosylation |
| RS757453683 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Intrauterine growth retardation |
| RS757453900 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Brain small vessel disease 1 with or without ocular anomalies, Brain small vessel disease 1 with or without ocular anomalies |
| RS757454147 |
LRRK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Parkinson disease 8, Inborn genetic diseases |
| RS757454595 |
FUS
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 6, Tremor |
| RS757456211 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS757456261 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
CBL-related disorder, RASopathy |
| RS757457793 |
TRIOBP
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 28, Autosomal recessive nonsyndromic hearing loss 28 |
| RS757457825 |
BCKDHA
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease |
| RS757458333 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS757458581 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 14 |
| RS757458607 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS757458960 |
TIMP3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757460257 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness, Hearing loss |
| RS757460628 |
DNMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Beckwith-Wiedemann syndrome, Hereditary sensory neuropathy-deafness-dementia syndrome |
| RS757460662 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS757461439 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757461540 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary diffuse gastric adenocarcinoma |
| RS757463918 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Vesicoureteral reflux 8, Ehlers-Danlos syndrome due to tenascin-X deficiency |
| RS757464167 |
RFX5
|
Health Risk |
Pathogenic |
MHC class II deficiency, MHC class II deficiency |
| RS757464411 |
CFI
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome with I factor anomaly, Atypical hemolytic-uremic syndrome with I factor anomaly |
| RS757464563 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 71, Short-rib thoracic dysplasia 10 with or without polydactyly |
| RS757464897 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS757465924 |
RAB34
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, Orofaciodigital syndrome 20 |
| RS757466000 |
SEMA4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Cone-rod dystrophy 10 |
| RS757467776 |
ALG8
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG8 congenital disorder of glycosylation, ALG8 congenital disorder of glycosylation |
| RS757468756 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS757469488 |
DIAPH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 1, Progressive microcephaly-seizures-cortical blindness-developmental delay syndrome |
| RS75746974 |
ATP6V0A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa with osteodystrophy, ALG9 congenital disorder of glycosylation |
| RS757469887 |
CAPN3
|
Health Risk |
Likely pathogenic |
Muscular dystrophy, limb-girdle |
| RS757470639 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS757470958 |
CNGA3
|
Health Risk |
Pathogenic |
Retinal dystrophy, Achromatopsia 2 |
| RS757471063 |
SLC24A1
|
Health Risk |
Pathogenic |
— |
| RS757471117 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS757471313 |
PRCD
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS75747149 |
AXIN2
|
Health Risk |
Likely pathogenic |
Colorectal cancer, Colorectal cancer |
| RS757471501 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 2, Cardiomyopathy |
| RS757471928 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS757473634 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS757473977 |
WNK2
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS757475739 |
VPS13C
|
Health Risk |
Likely pathogenic |
— |
| RS757475924 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS757477471 |
NPC1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type C1 |
| RS757478410 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS757478752 |
TREX1
|
Health Risk |
Likely pathogenic |
Aicardi-Goutieres syndrome 1, Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations |
| RS757479184 |
APPL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 14, Maturity-onset diabetes of the young type 14 |
| RS757479262 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS757479364 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Inborn genetic diseases |
| RS757480516 |
PDXK
|
Health Risk |
Pathogenic |
Neuropathy, hereditary motor and sensory |
| RS757480645 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS757481015 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS757481230 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy |
| RS757481572 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, CTNNA1-related disorder |
| RS757481998 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS757482211 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dystrophin deficiency |
| RS757482428 |
TRAPPC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 13 |
| RS757482856 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS757482925 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Cardiovascular phenotype |
| RS757483045 |
LOC129992304;QDPR
|
Health Risk |
Likely pathogenic |
Dihydropteridine reductase deficiency, Dihydropteridine reductase deficiency |
| RS757485456 |
GALNT12
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS757485757 |
TCTN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS757486099 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, DNAH11-related disorder |