| RS757610542 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital ichthyosis of skin, Congenital ichthyosis of skin |
| RS757611751 |
KERA
|
Health Risk |
Pathogenic |
Cornea plana 2, Cornea plana 2 |
| RS757613660 |
GNPTAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS757613811 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS757613817 |
NSMCE2
|
Health Risk |
Pathogenic |
Seckel syndrome 10, Seckel syndrome 10 |
| RS757614405 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS757615089 |
POLR3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukodystrophy, hypomyelinating |
| RS757615099 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS757615298 |
L2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
L-2-hydroxyglutaric aciduria, Inborn genetic diseases |
| RS757615745 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS75761674 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Inborn genetic diseases |
| RS757617349 |
LAMC2
|
Health Risk |
Likely pathogenic |
Junctional epidermolysis bullosa gravis of Herlitz, Junctional epidermolysis bullosa gravis of Herlitz |
| RS757617999 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS757621175 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS757621444 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS757622521 |
PDE6C
|
Health Risk |
Pathogenic |
Achromatopsia, Cone dystrophy 4 |
| RS757622849 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS757625535 |
USH1C
|
Health Risk |
Pathogenic |
— |
| RS757625928 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS757626317 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757627281 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Myopathy |
| RS757628476 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS75762896 |
PKD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease 2, Autosomal dominant polycystic kidney disease |
| RS757629380 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS757629526 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS757630877 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS757630901 |
VPS13C
|
Health Risk |
Pathogenic |
— |
| RS757631449 |
STIL
|
Health Risk |
Likely pathogenic |
Neutrophil inclusion bodies, Neutrophil inclusion bodies |
| RS757631575 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS757632129 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS757632931 |
CIITA
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class II deficiency, Inborn genetic diseases |
| RS757632961 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS75763304 |
BUB1B
|
Health Risk |
Pathogenic |
Mosaic variegated aneuploidy syndrome 1, Mosaic variegated aneuploidy syndrome 1 |
| RS757633174 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS75763344 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS757634052 |
P3H1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type 8, Osteogenesis imperfecta type 8 |
| RS757635140 |
DIAPH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 1, Progressive microcephaly-seizures-cortical blindness-developmental delay syndrome |
| RS757635528 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS757636155 |
TRAPPC12
|
Health Risk |
Likely pathogenic |
Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome, Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome |
| RS757636363 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS757636489 |
TUBGCP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Microcephaly and chorioretinopathy 1 |
| RS757636745 |
SPATA7
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 3, Retinitis pigmentosa |
| RS757641323 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephronophthisis, Meckel-Gruber syndrome |
| RS757642790 |
OTOF
|
Health Risk |
Pathogenic |
— |
| RS757643586 |
ABHD12
|
Health Risk |
Pathogenic |
— |
| RS757643633 |
NANOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757644888 |
KCNJ1
|
Health Risk |
Likely pathogenic |
— |
| RS757645341 |
ACVRL1
|
Health Risk |
Pathogenic |
Telangiectasia, hereditary hemorrhagic |
| RS757647065 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BRCA2-related cancer predisposition |
| RS757647232 |
LAMB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa, Junctional epidermolysis bullosa |
| RS757648006 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniosynostosis syndrome, Beare-Stevenson cutis gyrata syndrome |
| RS757648761 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
DiGeorge syndrome, Cardiovascular phenotype |
| RS757649304 |
CUL4B
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked intellectual disability Cabezas type, Inborn genetic diseases |
| RS757649673 |
CUBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Imerslund-Grasbeck syndrome, Proteinuria |
| RS757649757 |
MARS2
|
Health Risk |
Likely pathogenic |
— |
| RS757650055 |
CNGA3
|
Health Risk |
Likely pathogenic |
Achromatopsia 2, Retinal dystrophy |
| RS757650373 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Transitory neonatal diabetes mellitus, Maturity-onset diabetes of the young |
| RS757650990 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS757651507 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757651881 |
FUS
|
Health Risk |
Conflicting classifications of pathogenicity |
Tremor, hereditary essential |
| RS757652435 |
DNHD1
|
Health Risk |
Pathogenic |
— |
| RS757652918 |
SAMD9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757653002 |
PLCH1
|
Health Risk |
Pathogenic |
Holoprosencephaly 14, Holoprosencephaly 14 |
| RS757653154 |
FBP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fructose-biphosphatase deficiency, Inborn genetic diseases |
| RS757653472 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757653982 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS757655010 |
GBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type IV |
| RS757655633 |
PARN
|
Health Risk |
Conflicting classifications of pathogenicity |
Pulmonary fibrosis and/or bone marrow failure, Telomere-related |
| RS757657013 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS757657323 |
AP4E1
|
Health Risk |
Pathogenic/Likely pathogenic |
Spastic paraplegia, Stuttering |
| RS757658720 |
TGM1
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS757658916 |
PEX14
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, complementation group K |
| RS757660866 |
MYO3A
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS757661749 |
LAMA2
|
Health Risk |
Pathogenic |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS757662453 |
SLX4
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group P, Fanconi anemia |
| RS757663357 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS757663389 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, 6 conditions |
| RS757664433 |
TGFB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Rienhoff syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS757665544 |
NR2E3
|
Health Risk |
Likely pathogenic |
Enhanced S-cone syndrome, Enhanced S-cone syndrome |
| RS757665750 |
NPHS2
|
Health Risk |
Pathogenic |
— |
| RS757666530 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
CODAS syndrome, LONP1-related disorder |
| RS757668134 |
FOXF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757668486 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757668497 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, Zellweger spectrum disorders |
| RS757669327 |
ZMYM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities, Congenital anomaly of kidney and urinary tract |
| RS757670984 |
ABHD12
|
Health Risk |
Pathogenic/Likely pathogenic |
See cases, See cases |
| RS757671025 |
HADHA
|
Health Risk |
Pathogenic |
Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency, Mitochondrial trifunctional protein deficiency |
| RS757672024 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS757673014 |
TNPO3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1F, Autosomal dominant limb-girdle muscular dystrophy type 1F |
| RS757674137 |
TOPORS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS757674160 |
NUP93
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephrotic syndrome, type 12 |
| RS757674263 |
NALCN
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Congenital contractures of the limbs and face |
| RS757674289 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa 1 |
| RS757675676 |
CDH23
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Pituitary adenoma 5 |
| RS757676098 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to CARD11 deficiency, BENTA disease |
| RS757676104 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS757676723 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS757676858 |
RERE
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with or without anomalies of the brain, eye |
| RS757677006 |
LMOD2
|
Health Risk |
Pathogenic |
Cardiomyopathy, dilated |
| RS757677789 |
AGRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 8, Inborn genetic diseases |