| RS757797994 |
RAG1
|
Health Risk |
Pathogenic |
Combined immunodeficiency with skin granulomas, Severe combined immunodeficiency |
| RS757799254 |
GALC
|
Health Risk |
Pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS757800887 |
MTRR
|
Health Risk |
Pathogenic |
Methylcobalamin deficiency type cblE, Methylcobalamin deficiency type cblE |
| RS757801770 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS757803046 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS75780325 |
VWA3B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757803941 |
FGF13
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual developmental disorder, X-linked 110 |
| RS757803976 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS757805966 |
TRDN
|
Health Risk |
Pathogenic/Likely pathogenic |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia |
| RS757807971 |
CC2D2A
|
Health Risk |
Pathogenic |
Meckel syndrome, type 6 |
| RS757808169 |
WRN
|
Health Risk |
Pathogenic/Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS757808220 |
GJB1
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth Neuropathy X, Charcot-Marie-Tooth Neuropathy X |
| RS757810589 |
SIN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757810767 |
MYO3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757811625 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 5, Developmental and epileptic encephalopathy |
| RS757816344 |
SBF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757816355 |
KRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, 12 conditions |
| RS757816546 |
COQ9
|
Health Risk |
Conflicting classifications of pathogenicity |
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome |
| RS757816953 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS757817018 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS757817254 |
F11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS757818559 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS757818801 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS757819428 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS757819771 |
ADAR
|
Health Risk |
Pathogenic |
— |
| RS757820442 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic Pulmonary Fibrosis, Dyskeratosis congenita |
| RS757820496 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Miyoshi muscular dystrophy 1 |
| RS757820624 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS757820671 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757820735 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS757821091 |
FBXO11
|
Health Risk |
Likely pathogenic |
Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities, Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities |
| RS757821270 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Malignant tumor of breast |
| RS757823284 |
TTLL5
|
Health Risk |
Pathogenic |
— |
| RS757823317 |
IFT122
|
Health Risk |
Conflicting classifications of pathogenicity |
Cranioectodermal dysplasia 1, Cranioectodermal dysplasia 1 |
| RS757823463 |
GUCY2D
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 6, Leber congenital amaurosis 1 |
| RS757823678 |
DNMT3A
|
Health Risk |
Pathogenic/Likely pathogenic |
Tatton-Brown-Rahman overgrowth syndrome, Inborn genetic diseases |
| RS757823891 |
CCDC39
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 14 |
| RS757824441 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS757825631 |
STAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital lipoid adrenal hyperplasia due to STAR deficency, Congenital lipoid adrenal hyperplasia due to STAR deficency |
| RS757825778 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS757826187 |
DPF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757827840 |
WDR62
|
Health Risk |
Pathogenic |
WDR62-related disorder, WDR62-related disorder |
| RS757828751 |
ASNS
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757829667 |
NPHS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 2 |
| RS757830349 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2K |
| RS75783175 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, MEGF10-related disorder |
| RS757832700 |
IVD
|
Health Risk |
Conflicting classifications of pathogenicity |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS757832991 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS757834403 |
SCAPER
|
Health Risk |
Likely pathogenic |
Intellectual developmental disorder and retinitis pigmentosa, IDDRP |
| RS75783492 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Decreased circulating carnitine concentration |
| RS757836263 |
SPTB
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spherocytosis type 2, Chudley-McCullough syndrome |
| RS757836340 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Elliptocytosis 2, Pyropoikilocytosis |
| RS757836789 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS757837763 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757838397 |
TWNK
|
Health Risk |
Likely pathogenic |
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 3 |
| RS757840030 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Congestive heart failure, Hypertrophic cardiomyopathy 14 |
| RS757840865 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS757840893 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial melanoma, Familial melanoma |
| RS757841012 |
BLM
|
Health Risk |
Likely pathogenic |
Bloom syndrome, Bloom syndrome |
| RS757841535 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS757843416 |
LTBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani syndrome, Glaucoma 3 |
| RS757845058 |
SPTA1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS757845999 |
SHOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Langer mesomelic dysplasia syndrome, Leri-Weill dyschondrosteosis |
| RS757846343 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757846451 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS757846582 |
DNAH5
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS757846841 |
NSD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757847164 |
BUB1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757847276 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS757847775 |
DNAH1
|
Health Risk |
Pathogenic |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS757848062 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS757848486 |
CDC20
|
Health Risk |
Pathogenic |
Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS757849047 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS757849639 |
STUB1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757849830 |
PKP2
|
Health Risk |
Pathogenic |
Arrhythmogenic right ventricular dysplasia 9, Arrhythmogenic right ventricular dysplasia 9 |
| RS757849893 |
RAB27A
|
Health Risk |
Pathogenic |
Griscelli syndrome type 2, Griscelli syndrome type 2 |
| RS757850587 |
SMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type A |
| RS757850760 |
PHOX2B
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS757851017 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS757852651 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS757852728 |
EIF2AK4
|
Health Risk |
Pathogenic |
Familial pulmonary capillary hemangiomatosis, Familial pulmonary capillary hemangiomatosis |
| RS757854282 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS757857101 |
MFSD8
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS757858465 |
PSMB8
|
Health Risk |
Conflicting classifications of pathogenicity |
Proteasome-associated autoinflammatory syndrome 1, Autoinflammatory syndrome |
| RS757858684 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS757858711 |
MERTK
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Inborn genetic diseases |
| RS757859799 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757860001 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 5, primary |
| RS757860505 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Febrile seizures |
| RS757860628 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS757860709 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS757861047 |
KLF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital dyserythropoietic anemia type 4, Congenital dyserythropoietic anemia type 4 |
| RS757862609 |
INSL3
|
Health Risk |
Likely pathogenic |
Bilateral cryptorchidism, Bilateral cryptorchidism |
| RS757863128 |
WWOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 1 |
| RS757863670 |
B9D2
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome 34 |
| RS757865122 |
PMM2
|
Health Risk |
Pathogenic |
PMM2-congenital disorder of glycosylation, PMM2-congenital disorder of glycosylation |
| RS757865136 |
SLC29A3
|
Health Risk |
Conflicting classifications of pathogenicity |
H syndrome, H syndrome |
| RS757868659 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS757868774 |
GABRG2
|
Health Risk |
Conflicting classifications of pathogenicity |
EPILEPSY, CHILDHOOD ABSENCE |
| RS757868800 |
KCNE5
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Brugada syndrome |