| RS757869728 |
OBSL1
|
Health Risk |
Pathogenic |
— |
| RS757870208 |
GALNS
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-A |
| RS757870729 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Inborn genetic diseases |
| RS757870828 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS757870881 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, Inborn genetic diseases |
| RS757870894 |
QRICH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Ververi-Brady syndrome 1 |
| RS757872564 |
RECQL4
|
Health Risk |
Pathogenic |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS757872635 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Charlevoix-Saguenay spastic ataxia |
| RS757874547 |
DGUOK
|
Health Risk |
Pathogenic |
— |
| RS757874580 |
LARP7
|
Health Risk |
Pathogenic |
Microcephalic primordial dwarfism, Alazami type |
| RS757874631 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS757875136 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS757877367 |
KCNJ5
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS757877420 |
COG8
|
Health Risk |
Conflicting classifications of pathogenicity |
COG8-congenital disorder of glycosylation, Inborn genetic diseases |
| RS757878946 |
ABCB4
|
Health Risk |
Likely pathogenic |
— |
| RS757879229 |
TAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Tyrosinemia type II, Tyrosinemia type II |
| RS757881397 |
CPT2
|
Health Risk |
Pathogenic |
Carnitine palmitoyltransferase II deficiency, Carnitine palmitoyltransferase II deficiency |
| RS757881983 |
SLC16A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Allan-Herndon-Dudley syndrome |
| RS757882235 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS757883156 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 9, Atypical hemolytic-uremic syndrome with C3 anomaly |
| RS757883355 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS757883779 |
SETX
|
Health Risk |
Pathogenic |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS757883936 |
HPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome 1 |
| RS757884073 |
HMGCL
|
Health Risk |
Likely pathogenic |
Deficiency of hydroxymethylglutaryl-CoA lyase, Deficiency of hydroxymethylglutaryl-CoA lyase |
| RS757886671 |
MPDZ
|
Health Risk |
Likely pathogenic |
— |
| RS757886838 |
TECTA
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 21, Autosomal recessive nonsyndromic hearing loss 21 |
| RS757888034 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, 6 conditions |
| RS757888349 |
SGCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy |
| RS757888367 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS757888672 |
GCK
|
Health Risk |
Pathogenic |
— |
| RS757890568 |
MED17
|
Health Risk |
Likely pathogenic |
— |
| RS757890592 |
CACNA1E
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757891932 |
ARSA
|
Health Risk |
Pathogenic/Likely pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS757892928 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 1 |
| RS757892950 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Inborn genetic diseases |
| RS757893642 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS757893762 |
SI
|
Health Risk |
Likely pathogenic |
Sucrase-isomaltase deficiency, Sucrase-isomaltase deficiency |
| RS757893794 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS757893858 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Glycogen storage disease |
| RS757894483 |
COL4A5
|
Health Risk |
Likely pathogenic |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS757894912 |
SACS
|
Health Risk |
Pathogenic |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS757895481 |
RECQL
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757895588 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS757896094 |
CUL4B
|
Health Risk |
Conflicting classifications of pathogenicity |
CUL4B-related disorder, Inborn genetic diseases |
| RS757896781 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS757896867 |
MYO7A
|
Health Risk |
Pathogenic |
Usher syndrome type 1B, Usher syndrome type 1B |
| RS757897959 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Zellweger spectrum disorders |
| RS757898834 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757899517 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2A1 |
| RS757899657 |
APOA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial visceral amyloidosis, Ostertag type |
| RS757899755 |
ACAD8
|
Health Risk |
Likely pathogenic |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS757899954 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, LONP1-related disorder |
| RS757900087 |
IMPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS757900380 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Hypertrophic cardiomyopathy 6 |
| RS757900399 |
AIPL1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 4, Leber congenital amaurosis 4 |
| RS757901425 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS757901877 |
CNTNAP1
|
Health Risk |
Pathogenic |
— |
| RS757902182 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS75790268 |
FGFR3
|
Health Risk |
Pathogenic |
Achondroplasia, Achondroplasia |
| RS757903212 |
USP9X
|
Health Risk |
Likely pathogenic |
— |
| RS757903559 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1 |
| RS757904271 |
COCH
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 9, Autosomal dominant nonsyndromic hearing loss 9 |
| RS757904452 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac anomalies - developmental delay - facial dysmorphism syndrome, Dextro-looped transposition of the great arteries |
| RS757905282 |
TGM1
|
Health Risk |
Likely pathogenic |
— |
| RS757905857 |
ACTG2
|
Health Risk |
Likely pathogenic |
Visceral myopathy 1, Visceral myopathy 1 |
| RS757905943 |
ACSF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS757906173 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS757909102 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757909121 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS757909285 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757910491 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757910571 |
JAK3
|
Health Risk |
Conflicting classifications of pathogenicity |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, T-B+ severe combined immunodeficiency due to JAK3 deficiency |
| RS757910862 |
PARN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal recessive 6 |
| RS757911359 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Myopathy |
| RS757912368 |
CHST6
|
Health Risk |
Pathogenic |
Macular corneal dystrophy, Macular corneal dystrophy |
| RS757912697 |
ALG3
|
Health Risk |
Likely pathogenic |
— |
| RS757912971 |
CTSA
|
Health Risk |
Pathogenic |
Combined deficiency of sialidase AND beta galactosidase, Malignant tumor of urinary bladder |
| RS757913217 |
SOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Anophthalmia/microphthalmia-esophageal atresia syndrome, Anophthalmia/microphthalmia-esophageal atresia syndrome |
| RS757914735 |
EVC2
|
Health Risk |
Pathogenic/Likely pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS757914881 |
ATP2A2
|
Health Risk |
Pathogenic |
— |
| RS757914897 |
P4HTM
|
Health Risk |
Likely pathogenic |
Intellectual disability, Intellectual disability |
| RS757915171 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS757916299 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS757917082 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS757917115 |
F5
|
Health Risk |
Pathogenic |
Congenital factor V deficiency, Factor V deficiency |
| RS757917155 |
TRPM1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS757917276 |
CSF3R
|
Health Risk |
Likely pathogenic |
— |
| RS757917335 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS757917876 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS757918162 |
LTBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glaucoma 3, primary congenital |
| RS757918826 |
AMT
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 2 |
| RS757918924 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS757919500 |
ARID1A
|
Health Risk |
Pathogenic |
— |
| RS757920082 |
LIPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolman disease, LIPA-related disorder |
| RS757920190 |
CBS
|
Health Risk |
Pathogenic/Likely pathogenic |
Homocystinuria, Classic homocystinuria |
| RS757923791 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS757925208 |
PROC
|
Health Risk |
Pathogenic |
Thrombophilia due to protein C deficiency, autosomal dominant |
| RS757925979 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS757926043 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS757926581 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
GM1 gangliosidosis, Mucopolysaccharidosis |