CDC20 Chromosome 1
Cell division cycle 20
Upload your DNA to see your personal genotypes for variants in CDC20.
What This Gene Does
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
WD repeat domain containing
Locus Type
gene with protein product
Location
1p34.2
Ensembl
ENSG00000117399
Associated Conditions (2)
Oocyte maturation defect 14
Clear cell carcinoma of kidney
Key Variants
RS752709238
Likely pathogenic
Oocyte maturation defect 14, Clear cell carcinoma of kidney, Oocyte maturation defect 14
Health Risk
RS1309457938
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS140305765
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS2545698654
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS2545698940
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS2545699267
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS372597302
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS754957702
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS757848486
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS760334505
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
RS766199335
Pathogenic
Oocyte maturation defect 14, Oocyte maturation defect 14
Health Risk
All Variants (11)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS752709238 | Health Risk | Likely pathogenic | Oocyte maturation defect 14, Clear cell carcinoma of kidney, Oocyte maturation defect 14 |
| RS1309457938 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS140305765 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS2545698654 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS2545698940 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS2545699267 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS372597302 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS754957702 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS757848486 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS760334505 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |
| RS766199335 | Health Risk | Pathogenic | Oocyte maturation defect 14, Oocyte maturation defect 14 |