| RS757556640 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS757556996 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Lethal congenital glycogen storage disease of heart |
| RS757557272 |
ABCA4
|
Health Risk |
Pathogenic |
Retinal dystrophy, Cone-rod dystrophy 3 |
| RS757558416 |
PDX1
|
Health Risk |
Uncertain risk allele |
Pancreatic hypoplasia, Pancreatic hypoplasia |
| RS757559168 |
SUOX
|
Health Risk |
Pathogenic |
Sulfite oxidase deficiency, Sulfocysteinuria |
| RS757559365 |
OPTN
|
Health Risk |
Pathogenic |
Primary open angle glaucoma, Glaucoma 1 |
| RS757559474 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Carcinoma of colon, Hereditary cancer-predisposing syndrome |
| RS757559806 |
LTBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani syndrome, Glaucoma 3 |
| RS757560062 |
KRIT1
|
Health Risk |
Pathogenic |
Cerebral cavernous malformation, Cerebral cavernous malformation |
| RS757560169 |
ADGRV1
|
Health Risk |
Likely pathogenic |
Idiopathic generalized epilepsy, Idiopathic generalized epilepsy |
| RS757560526 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS757562094 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757563721 |
MTMR2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4 |
| RS757563981 |
SGSH
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-A |
| RS757565418 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS757566117 |
ACBD6
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with progressive movement abnormalities, Neurodevelopmental disorder with progressive movement abnormalities |
| RS757566490 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757567225 |
FANCD2
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS757567429 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS757567654 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS757568270 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Norman-Roberts syndrome |
| RS757569345 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS757569691 |
HPS3
|
Health Risk |
Likely pathogenic |
— |
| RS757569717 |
TUFM
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 4, Combined oxidative phosphorylation defect type 4 |
| RS757570230 |
CD36
|
Health Risk |
Conflicting classifications of pathogenicity |
Platelet-type bleeding disorder 10, Platelet-type bleeding disorder 10 |
| RS757570584 |
EVC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS757571398 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS757571550 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 3 |
| RS757574487 |
SMC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cornelia de Lange syndrome 3 |
| RS757574546 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS757574720 |
GNPTAB
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS757575448 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS757575602 |
CENPF
|
Health Risk |
Pathogenic |
Stromme syndrome, Stromme syndrome |
| RS757575787 |
ATR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757575874 |
ACY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aminoacylase 1 deficiency, Aminoacylase 1 deficiency |
| RS757576013 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757576125 |
LMNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adult-onset autosomal dominant demyelinating leukodystrophy, Microcephaly 26 |
| RS757576159 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS757576348 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS757576841 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS757577112 |
TPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Left ventricular noncompaction cardiomyopathy, Hypertrophic cardiomyopathy |
| RS757577162 |
PCNT
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS757577323 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS757577670 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS757577741 |
ASH1L
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 52 |
| RS757578045 |
FANCF
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS757578262 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS757578685 |
NPHP3
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS757579310 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis syndrome, Hereditary cancer-predisposing syndrome |
| RS757579341 |
DDX11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757579833 |
CEP164
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 15, Inborn genetic diseases |
| RS757579891 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS757581909 |
GNPTG
|
Health Risk |
Pathogenic |
— |
| RS757583061 |
TWNK
|
Health Risk |
Likely pathogenic |
Auditory neuropathy, Auditory neuropathy |
| RS757583515 |
DHTKD1
|
Health Risk |
Likely pathogenic |
DHTKD1-related disorder, DHTKD1-related disorder |
| RS757583846 |
PROC
|
Health Risk |
Pathogenic/Likely pathogenic |
Thrombophilia due to protein C deficiency, autosomal dominant |
| RS757583944 |
KCNQ3
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial neonatal |
| RS757584252 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS757585091 |
ACTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757585784 |
CAD
|
Health Risk |
Likely pathogenic |
Ovarian serous cystadenocarcinoma, Ovarian serous cystadenocarcinoma |
| RS757586383 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS757588621 |
ARX
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 1 |
| RS757588716 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757589247 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS757589473 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2Q, Epidermolysis bullosa simplex with nail dystrophy |
| RS757589571 |
IGF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Growth delay due to insulin-like growth factor I resistance, Growth delay due to insulin-like growth factor I resistance |
| RS757589705 |
FGD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757590541 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757590581 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS757591029 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757591797 |
RAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Noonan syndrome and Noonan-related syndrome |
| RS757593086 |
CPT1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine palmitoyl transferase 1A deficiency, Inborn genetic diseases |
| RS757593576 |
CSTB
|
Health Risk |
Conflicting classifications of pathogenicity |
Unverricht-Lundborg syndrome, Progressive myoclonic epilepsy |
| RS757594906 |
RPGRIP1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS757597315 |
PSTPIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Pyogenic arthritis-pyoderma gangrenosum-acne syndrome |
| RS757598882 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS757598952 |
ICOS
|
Health Risk |
Likely pathogenic |
Immunodeficiency, common variable |
| RS757600041 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Charcot-Marie-Tooth disease |
| RS757600616 |
WARS2
|
Health Risk |
Likely pathogenic |
WARS2-related disorder, Neurodevelopmental disorder |
| RS757600961 |
DST
|
Health Risk |
Likely pathogenic |
Hereditary sensory and autonomic neuropathy type 6, Epidermolysis bullosa simplex 3 |
| RS757601640 |
DNAH17
|
Health Risk |
Likely pathogenic |
DNAH17-related disorder, DNAH17-related disorder |
| RS757601923 |
EZH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Weaver syndrome, Weaver syndrome |
| RS757602412 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital ichthyosis of skin, Congenital ichthyosis of skin |
| RS757602565 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS757603372 |
DYRK1A
|
Health Risk |
Conflicting classifications of pathogenicity |
DYRK1A-related intellectual disability syndrome, Inborn genetic diseases |
| RS757603460 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS757603534 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS757604577 |
NDE1
|
Health Risk |
Pathogenic |
Lissencephaly 4, Lissencephaly 4 |
| RS757604614 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS757605574 |
PKHD1
|
Health Risk |
Likely pathogenic |
Polycystic kidney disease 4, Polycystic kidney disease 4 |
| RS757605946 |
ALDH5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS757606065 |
AICDA
|
Health Risk |
Pathogenic |
Hyper-IgM syndrome type 2, Hyper-IgM syndrome type 2 |
| RS757606682 |
ENO3
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease due to muscle beta-enolase deficiency, Glycogen storage disease due to muscle beta-enolase deficiency |
| RS757606922 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS757607352 |
STXBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS757607501 |
ASPA
|
Health Risk |
Likely pathogenic |
Spongy degeneration of central nervous system, Spongy degeneration of central nervous system |
| RS757608100 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS757608461 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757608620 |
GAA
|
Health Risk |
Pathogenic |
— |
| RS757609119 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |