| RS761621368 |
CLN8
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis, Inborn genetic diseases |
| RS761621516 |
GAMT
|
Health Risk |
Pathogenic |
Gaucher disease type I, Gaucher disease type II |
| RS761621587 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS761622153 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS761622304 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS761622550 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital multicore myopathy with external ophthalmoplegia, Central core myopathy |
| RS761622978 |
AIPL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Leber congenital amaurosis 4 |
| RS761623564 |
NPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Acromesomelic dysplasia 1, Maroteaux type |
| RS761623610 |
ADAMTSL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Ectopia lentis 2, isolated |
| RS761625006 |
PCCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS761628767 |
NR2E3
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 37, Enhanced S-cone syndrome |
| RS761629258 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Familial hypercholesterolemia |
| RS761629787 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS761630483 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Respiratory ciliopathies including non-CF bronchiectasis |
| RS761630560 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS761630796 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761631513 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761631713 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS761631783 |
GALNT12
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761631813 |
SELENON
|
Health Risk |
Likely pathogenic |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS761632029 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS761632870 |
ARX
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked lissencephaly with abnormal genitalia, Partington syndrome |
| RS761633407 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS76163360 |
SMN1
|
Health Risk |
Pathogenic |
Werdnig-Hoffmann disease, Werdnig-Hoffmann disease |
| RS761634030 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Familial adenomatous polyposis 1 |
| RS761634052 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS761634625 |
NGLY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation 1 |
| RS761635539 |
TUBB4A
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypomyelinating leukodystrophy 6, Hypomyelinating leukodystrophy 6 |
| RS761635725 |
TNXB
|
Health Risk |
Likely pathogenic |
Vesicoureteral reflux 8, Vesicoureteral reflux 8 |
| RS761635767 |
CIZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dystonic disorder, Dystonic disorder |
| RS761636251 |
ANKRD11
|
Health Risk |
Pathogenic |
KBG syndrome, KBG syndrome |
| RS761636459 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Hereditary spastic paraplegia 48 |
| RS761637319 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS761637559 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761637940 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS761638957 |
GALK1
|
Health Risk |
Likely pathogenic |
Deficiency of galactokinase, Deficiency of galactokinase |
| RS761639530 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS761640153 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated Nonsyndromic Congenital Heart Disease, Alagille syndrome due to a JAG1 point mutation |
| RS761640192 |
FCHO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761643896 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS761645282 |
FA2H
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS761645724 |
OCRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Dent disease type 2, Lowe syndrome |
| RS761645932 |
PHKB
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease IXb, Glycogen phosphorylase kinase deficiency |
| RS761646754 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS761647447 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dilated cardiomyopathy 3B |
| RS761648454 |
MARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency, Charcot-Marie-Tooth disease axonal type 2U |
| RS761649878 |
POLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive sclerosing poliodystrophy, POLG-related disorder |
| RS761650208 |
CAT
|
Health Risk |
Pathogenic |
Acatalasemia, japanese type |
| RS761650400 |
MYLK3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761650522 |
BIVM-ERCC5;ERCC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group G |
| RS761651126 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS761651233 |
PRF1
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Aplastic anemia |
| RS761651320 |
ASL
|
Health Risk |
Pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS761651331 |
TREX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 1, Chilblain lupus 1 |
| RS761652195 |
SLC10A2
|
Health Risk |
Conflicting classifications of pathogenicity |
SLC10A2-related disorder, SLC10A2-related disorder |
| RS761653387 |
BRIP1
|
Health Risk |
Likely pathogenic |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS761653490 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS761655321 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Charlevoix-Saguenay spastic ataxia |
| RS761656607 |
NLRP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761656636 |
EFEMP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Cutis laxa, autosomal recessive |
| RS761657434 |
ADAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 6, Symmetrical dyschromatosis of extremities |
| RS761658541 |
SERAC1
|
Health Risk |
Pathogenic |
3-methylglutaconic aciduria with deafness, encephalopathy |
| RS761660130 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761661253 |
CEP78
|
Health Risk |
Pathogenic/Likely pathogenic |
Cone-rod dystrophy and hearing loss 1, Retinal dystrophy |
| RS761661864 |
ETHE1
|
Health Risk |
Likely pathogenic |
Ethylmalonic encephalopathy, Ethylmalonic encephalopathy |
| RS761661933 |
REST
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761662406 |
CDKL5
|
Health Risk |
Conflicting classifications of pathogenicity |
Angelman syndrome-like, Developmental and epileptic encephalopathy |
| RS761662654 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS761663690 |
CNTNAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cortical dysplasia-focal epilepsy syndrome, Cortical dysplasia-focal epilepsy syndrome |
| RS761663786 |
SCNN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761663976 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS761664802 |
POLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive sclerosing poliodystrophy, Sensory ataxic neuropathy |
| RS761664847 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS761665399 |
SLX4
|
Health Risk |
Likely pathogenic |
— |
| RS761665644 |
TYMP
|
Health Risk |
Pathogenic |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS761665772 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Occult macular dystrophy, Inborn genetic diseases |
| RS761666021 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS761666105 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761666344 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS761667882 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761668228 |
CTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Dyskeratosis congenita |
| RS761669036 |
ETFDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Glutaric acidemia type 2C |
| RS761669332 |
IFNAR2
|
Health Risk |
Pathogenic |
— |
| RS761669740 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS761670478 |
AGT
|
Health Risk |
Conflicting classifications of pathogenicity |
Anhydramnios, Renal tubular dysgenesis of genetic origin |
| RS761670755 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761672073 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome |
| RS761673241 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761673463 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS761674579 |
ZMYND10
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Inborn genetic diseases |
| RS761674987 |
SMARCC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autism spectrum disorder, Inborn genetic diseases |
| RS761676028 |
BBS9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 9 |
| RS761677945 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Cardiomyopathy |
| RS761681684 |
COL4A6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761683856 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS761684028 |
SGPL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome 14, Nephrotic syndrome 14 |
| RS761684626 |
HNF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Maturity-onset diabetes of the young |
| RS761684970 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Freeman-Sheldon syndrome, Distal arthrogryposis type 2B1 |
| RS761685529 |
LZTR1
|
Health Risk |
Pathogenic |
Noonan syndrome 2, Cardiovascular phenotype |
| RS761686437 |
COL4A3
|
Health Risk |
Likely pathogenic |
Autosomal recessive Alport syndrome, Autosomal dominant Alport syndrome |