| RS761487760 |
SZT2
|
Health Risk |
Pathogenic |
— |
| RS761488596 |
CYP11B1
|
Health Risk |
Likely pathogenic |
Deficiency of steroid 11-beta-monooxygenase, Deficiency of steroid 11-beta-monooxygenase |
| RS761489014 |
ADSS1
|
Health Risk |
Likely pathogenic |
Colon adenocarcinoma, Colon adenocarcinoma |
| RS761489812 |
HARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS761490126 |
SPINK5
|
Health Risk |
Likely pathogenic |
Netherton syndrome, Netherton syndrome |
| RS761490797 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 2, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS761491293 |
CACNA1C
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with hypotonia, language delay |
| RS761491320 |
GCDH
|
Health Risk |
Pathogenic |
Glutaric aciduria, type 1 |
| RS761491947 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS761492600 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group B, VACTERL association |
| RS761493072 |
ELP1
|
Health Risk |
Pathogenic |
— |
| RS761493155 |
ADSL
|
Health Risk |
Pathogenic |
Adenylosuccinate lyase deficiency, Adenylosuccinate lyase deficiency |
| RS761494200 |
ACSF3
|
Health Risk |
Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS761494650 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS761495014 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS761495177 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental delay with variable intellectual impairment and behavioral abnormalities, Developmental delay with variable intellectual impairment and behavioral abnormalities |
| RS761496130 |
NR5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligosynaptic infertility, 46 |
| RS761496908 |
KNG1
|
Health Risk |
Pathogenic |
High molecular weight kininogen deficiency, High molecular weight kininogen deficiency |
| RS761499667 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS761500193 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PIEZO1-related disorder |
| RS761500258 |
CC2D1A
|
Health Risk |
Pathogenic |
— |
| RS761501958 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS761502278 |
MLC1
|
Health Risk |
Likely pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts 1 |
| RS761502781 |
RTTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761502897 |
CPLANE1
|
Health Risk |
Pathogenic |
— |
| RS761503137 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Saldino-Mainzer syndrome |
| RS761503203 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS761503297 |
UBQLN2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761504128 |
CD27
|
Health Risk |
Likely pathogenic |
— |
| RS761504464 |
IFT172
|
Health Risk |
Likely pathogenic |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS761505217 |
SCN5A
|
Health Risk |
Pathogenic/Likely pathogenic |
Brugada syndrome, Cardiovascular phenotype |
| RS761505231 |
ZMYND10
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS761505396 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS761505485 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Sick sinus syndrome 1, Dilated cardiomyopathy 1E |
| RS761505767 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS761507504 |
CSRP3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypertrophic cardiomyopathy 12, Dilated cardiomyopathy 1M |
| RS761508149 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS761508385 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761511141 |
ACOX1
|
Health Risk |
Likely pathogenic |
Mitchell syndrome, Mitchell syndrome |
| RS761512189 |
NF1
|
Health Risk |
Likely pathogenic |
Neurofibromatosis, type 1 |
| RS761512367 |
TYK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 35, Immunodeficiency 35 |
| RS761515078 |
PPA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761515593 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS761515806 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS761516140 |
TRNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome, Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome |
| RS761516178 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS76151636 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Inborn genetic diseases |
| RS761516512 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS761516738 |
LAMC3
|
Health Risk |
Likely pathogenic |
Occipital pachygyria and polymicrogyria, Occipital pachygyria and polymicrogyria |
| RS761516740 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS761517421 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune interstitial lung disease-arthritis syndrome, Inborn genetic diseases |
| RS76151804 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS761519187 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypocalciuric hypercalcemia, Autosomal dominant hypocalcemia 1 |
| RS761519681 |
CACNA1D
|
Health Risk |
Conflicting classifications of pathogenicity |
CACNA1D-related disorder, CACNA1D-related disorder |
| RS761519693 |
FLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS761519737 |
FANCG
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group G, Fanconi anemia |
| RS761522694 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS761523326 |
KCNH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, Early-infantile DEE |
| RS761523501 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761524468 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761524542 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS761524773 |
TMC8
|
Health Risk |
Likely pathogenic |
Epidermodysplasia verruciformis, Epidermodysplasia verruciformis |
| RS761525156 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic acidemia |
| RS761526890 |
KCNJ8
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS761527468 |
KARS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukoencephalopathy, progressive |
| RS761528498 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761528809 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS761529282 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS761529786 |
DHTKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
2-aminoadipic 2-oxoadipic aciduria, Inborn genetic diseases |
| RS761530861 |
SLC26A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrolithiasis susceptibility caused by SLC26A1, Hypersulfaturia |
| RS761531039 |
TRPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness 1C, Congenital stationary night blindness 1C |
| RS761531673 |
ASH1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 52 |
| RS761532715 |
PKDCC
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Rhizomelic limb shortening with dysmorphic features |
| RS761533286 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS761533681 |
SLC1A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome, Inborn genetic diseases |
| RS761533713 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease due to ABCA3 deficiency, Hereditary pulmonary alveolar proteinosis |
| RS761533717 |
GPR179
|
Health Risk |
Likely pathogenic |
— |
| RS761534024 |
VCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1W, Cardiovascular phenotype |
| RS76153575 |
LRSAM1
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease, Familial pancreatic carcinoma |
| RS761542135 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS761542502 |
AMPD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 63, Pontocerebellar hypoplasia type 9 |
| RS761542549 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Inborn genetic diseases |
| RS761543313 |
PIGH
|
Health Risk |
Pathogenic |
Glycosylphosphatidylinositol biosynthesis defect 17, Glycosylphosphatidylinositol biosynthesis defect 17 |
| RS761543680 |
GIPC3
|
Health Risk |
Pathogenic |
Hearing loss, autosomal recessive |
| RS761544365 |
GJC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hypomyelinating leukodystrophy 2 |
| RS761544849 |
CUL7
|
Health Risk |
Pathogenic |
— |
| RS761545315 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, Autoinflammatory syndrome |
| RS761545816 |
SCP2
|
Health Risk |
Conflicting classifications of pathogenicity |
SCP2-related disorder, SCP2-related disorder |
| RS761545914 |
MYBPC3
|
Health Risk |
Pathogenic |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS761546140 |
PJVK
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 59, Autosomal recessive nonsyndromic hearing loss 59 |
| RS761546594 |
CTRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS761546902 |
SMARCAL1
|
Health Risk |
Pathogenic |
Schimke immuno-osseous dysplasia, SMARCAL1-related disorder |
| RS761547193 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease 4, Polycystic kidney disease 4 |
| RS761549734 |
DOCK6
|
Health Risk |
Likely pathogenic |
Adams-Oliver syndrome 2, Adams-Oliver syndrome 2 |
| RS761550284 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS761550303 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS761550940 |
TMC8
|
Health Risk |
Pathogenic |
Epidermodysplasia verruciformis, Epidermodysplasia verruciformis |
| RS761551156 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS761551284 |
ADSL
|
Health Risk |
Likely pathogenic |
Adenylosuccinate lyase deficiency, Adenylosuccinate lyase deficiency |
| RS761551642 |
KDM6A
|
Health Risk |
Likely pathogenic |
— |