| RS761345552 |
CIC
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 45 |
| RS761346369 |
PLOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bruck syndrome 2, Bruck syndrome 2 |
| RS761346761 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group B |
| RS761347179 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Hereditary cancer-predisposing syndrome |
| RS761347389 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Autosomal recessive Alport syndrome |
| RS761349153 |
GRXCR1
|
Health Risk |
Likely pathogenic |
Rare genetic deafness, Monogenic hearing loss |
| RS761349696 |
ANKH
|
Health Risk |
Conflicting classifications of pathogenicity |
Chondrocalcinosis 2, Craniometaphyseal dysplasia |
| RS761350391 |
BBS7
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 7, Bardet-Biedl syndrome |
| RS761350619 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder, ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder |
| RS761350633 |
SDHB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cowden syndrome, Gastrointestinal stromal tumor |
| RS761350690 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
PTEN hamartoma tumor syndrome, Hereditary cancer-predisposing syndrome |
| RS761350756 |
NPAT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761351091 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS761352737 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS761353188 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS761353511 |
ENG
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Hereditary hemorrhagic telangiectasia |
| RS761353617 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS761353734 |
PTCH1
|
Health Risk |
Likely pathogenic |
Gorlin syndrome, Gorlin syndrome |
| RS761354764 |
COG8
|
Health Risk |
Conflicting classifications of pathogenicity |
COG8-congenital disorder of glycosylation, COG8-congenital disorder of glycosylation |
| RS761355038 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS76135678 |
THBD
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome with thrombomodulin anomaly, Thrombomodulin-related bleeding disorder |
| RS761357250 |
ATF6
|
Health Risk |
Pathogenic |
Achromatopsia 7, ATF6-related disorder |
| RS761358728 |
COL4A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Alport syndrome, COL4A3-related disorder |
| RS761359247 |
ELAC2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 17, Combined oxidative phosphorylation defect type 17 |
| RS761360623 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS761360851 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic right ventricular dysplasia 10 |
| RS761362530 |
CYP4V2
|
Health Risk |
Pathogenic |
Bietti crystalline corneoretinal dystrophy, Retinal dystrophy |
| RS761364243 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS761364688 |
EXT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Exostoses, multiple |
| RS761365669 |
COX15
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761367363 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Usher syndrome type 2A |
| RS761368099 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761368190 |
ACO2
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS761368563 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS761370420 |
SLC25A13
|
Health Risk |
Pathogenic |
Citrullinemia type I, Citrin deficiency |
| RS761372687 |
ASAH1
|
Health Risk |
Pathogenic |
Farber lipogranulomatosis, Farber lipogranulomatosis |
| RS761372792 |
TGM1
|
Health Risk |
Likely pathogenic |
— |
| RS761374262 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS761375132 |
GLUD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinism-hyperammonemia syndrome, Inborn genetic diseases |
| RS761376417 |
THAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Torsion dystonia 6, Inborn genetic diseases |
| RS761378464 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS761378545 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Brugada syndrome 3 |
| RS761379794 |
ZNF469
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS761380468 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism type 2C, Neuropathy |
| RS761380652 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS761380979 |
DSP
|
Health Risk |
Pathogenic/Likely pathogenic |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS761382742 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS761382780 |
CSPP1
|
Health Risk |
Pathogenic |
Joubert syndrome 21, Joubert syndrome 21 |
| RS761383124 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Tibial muscular dystrophy |
| RS761385155 |
ELAC2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 17, Inborn genetic diseases |
| RS761385178 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 29 |
| RS761385192 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Morquio syndrome, Mucopolysaccharidosis |
| RS761385206 |
SCLT1
|
Health Risk |
Pathogenic |
— |
| RS761385278 |
DUOX2
|
Health Risk |
Pathogenic |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS761385416 |
CYP11B2
|
Health Risk |
Pathogenic/Likely pathogenic |
Corticosterone 18-monooxygenase deficiency, Corticosterone methyloxidase type 2 deficiency |
| RS761386159 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS761386688 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 13 |
| RS761388039 |
LAMC2
|
Health Risk |
Pathogenic |
Epidermolysis bullosa, junctional 3A |
| RS761388040 |
AHI1
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Joubert syndrome 3 |
| RS761388176 |
SLC38A8
|
Health Risk |
Pathogenic/Likely pathogenic |
Foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome, Foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome |
| RS761388824 |
DLC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761388922 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Ovarian serous cystadenocarcinoma |
| RS761389658 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS761389904 |
NDUFAF5
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Mitochondrial complex I deficiency |
| RS761390691 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS761390938 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS761391442 |
SMAD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aneurysm-osteoarthritis syndrome |
| RS761393058 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Congenital multicore myopathy with external ophthalmoplegia |
| RS761393259 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica inversa, autosomal recessive |
| RS761394437 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS761395846 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS761396172 |
GALNT3
|
Health Risk |
Pathogenic/Likely pathogenic |
Tumoral calcinosis, hyperphosphatemic |
| RS761397379 |
SLC12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 1, SLC12A1-related disorder |
| RS761398394 |
RMRP
|
Health Risk |
Likely pathogenic |
Metaphyseal chondrodysplasia, McKusick type |
| RS761399081 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS761399728 |
GNB5
|
Health Risk |
Pathogenic |
Global developmental delay, Delayed speech and language development |
| RS761400349 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 2 |
| RS761401027 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS761401181 |
KDM6B
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities, Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities |
| RS761401672 |
COQ8B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761402128 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS761402403 |
PIK3R1
|
Health Risk |
Pathogenic |
Overgrowth syndrome, Overgrowth syndrome |
| RS761403503 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS761403504 |
BBS7
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome 7, Bardet-Biedl syndrome |
| RS761403505 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS761404241 |
ESCO2
|
Health Risk |
Pathogenic/Likely pathogenic |
Roberts-SC phocomelia syndrome, Roberts-SC phocomelia syndrome |
| RS761405097 |
VCAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Vitreoretinopathy, Vitreoretinopathy |
| RS761405340 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS76140563 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS761406257 |
MEGF8
|
Health Risk |
Likely pathogenic |
MEGF8-related Carpenter syndrome, MEGF8-related Carpenter syndrome |
| RS761406918 |
ABCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
Dubin-Johnson syndrome, Dubin-Johnson syndrome |
| RS761407249 |
DNAAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS761407827 |
SPR
|
Health Risk |
Pathogenic |
Dystonic disorder, Dopa-responsive dystonia due to sepiapterin reductase deficiency |
| RS761408425 |
KCNK4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761409446 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 5 with or without anosmia, CHARGE syndrome |
| RS761410195 |
TBC1D8B
|
Health Risk |
Likely pathogenic |
Nephrotic syndrome, type 20 |
| RS761410250 |
GLRA1
|
Health Risk |
Likely pathogenic |
— |
| RS761410781 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS761410867 |
PUS1
|
Health Risk |
Conflicting classifications of pathogenicity |
PUS1-related disorder, PUS1-related disorder |
| RS761412178 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
BRCA2-related disorder, BRCA2-related disorder |