| RS761273297 |
VPS13B
|
Health Risk |
Pathogenic |
Cohen syndrome, Cohen syndrome |
| RS761273376 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS761274563 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1E, Long QT syndrome 3 |
| RS761275346 |
POU1F1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pituitary hormone deficiency, combined |
| RS761276607 |
SLC25A46
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary motor and sensory |
| RS761277865 |
PRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS761278503 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group J |
| RS761279421 |
RORB
|
Health Risk |
Pathogenic |
— |
| RS761281000 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS761281095 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS761282960 |
ACAT1
|
Health Risk |
Pathogenic |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS761283105 |
GFM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial disease, Combined oxidative phosphorylation deficiency 39 |
| RS761283836 |
TRPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness 1C, Congenital stationary night blindness 1C |
| RS761285440 |
TECPR2
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 49, Hereditary spastic paraplegia 49 |
| RS761285505 |
SBF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4B2 |
| RS761285716 |
PTS
|
Health Risk |
Pathogenic |
6-Pyruvoyl-tetrahydrobiopterin synthase deficiency, 6-Pyruvoyl-tetrahydrobiopterin synthase deficiency |
| RS761286207 |
RTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS761286590 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Optic atrophy |
| RS761287044 |
OTOG
|
Health Risk |
Pathogenic |
OTOG-related disorder, OTOG-related disorder |
| RS761288442 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS761288966 |
VWF
|
Health Risk |
Likely pathogenic |
Hereditary von Willebrand disease, Hereditary von Willebrand disease |
| RS761289479 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS761290075 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Hereditary spastic paraplegia 48 |
| RS761290111 |
CRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 2, Leber congenital amaurosis 7 |
| RS761291501 |
FANCL
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group L |
| RS761292021 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Retinal dystrophy |
| RS761292212 |
CYP11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Corticosterone methyl oxidase type II deficiency, Corticosterone 18-monooxygenase deficiency |
| RS761293997 |
PRF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Lymphoma, non-Hodgkin |
| RS761294614 |
WNK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism type 2B, Inborn genetic diseases |
| RS761295502 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761295534 |
PCCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Propionic acidemia, Propionic acidemia |
| RS761295869 |
ALDH7A1
|
Health Risk |
Likely pathogenic |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS761296880 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS761298089 |
TUBB4A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761298708 |
NPHS2
|
Health Risk |
Likely pathogenic |
— |
| RS761299690 |
GNPTG
|
Health Risk |
Conflicting classifications of pathogenicity |
GNPTG-mucolipidosis, GNPTG-mucolipidosis |
| RS761299898 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS761300463 |
FHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked myopathy with postural muscle atrophy, Cardiovascular phenotype |
| RS761302373 |
IL12RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency, Inborn genetic diseases |
| RS761302882 |
DYSF
|
Health Risk |
Pathogenic |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS761303232 |
FLG
|
Health Risk |
Pathogenic |
— |
| RS761304479 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS761308217 |
SMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type B |
| RS761308889 |
TINF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Revesz syndrome, Dyskeratosis congenita |
| RS761309470 |
STRADA
|
Health Risk |
Pathogenic |
Polyhydramnios, megalencephaly |
| RS761310644 |
PRF1
|
Health Risk |
Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Lymphoma |
| RS76131127 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS761312032 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, Brugada syndrome 5 |
| RS761312129 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial colorectal cancer type X, Polymerase proofreading-related adenomatous polyposis |
| RS761312526 |
WDPCP
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Heart defect - tongue hamartoma - polysyndactyly syndrome |
| RS761312704 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS761313165 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia |
| RS76131336 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS761314438 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Occult macular dystrophy, Inborn genetic diseases |
| RS761314760 |
SLX4
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group P, Fanconi anemia complementation group P |
| RS761317029 |
ACADM
|
Health Risk |
Pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS761317200 |
MN1
|
Health Risk |
Likely pathogenic |
CEBALID syndrome, MN1 C-terminal truncation (MCTT) syndrome |
| RS761317813 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS761319100 |
KCNQ5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761319935 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS761319979 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Central core myopathy, Congenital multicore myopathy with external ophthalmoplegia |
| RS761320331 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS761320763 |
WFS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Wolfram syndrome 1, Wolfram-like syndrome |
| RS761322350 |
ROBO1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS761323769 |
VPS13C
|
Health Risk |
Pathogenic |
— |
| RS76132393 |
SETD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Luscan-Lumish syndrome, Congenital portosystemic shunt |
| RS761324549 |
AUTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761325768 |
HS6ST1
|
Health Risk |
risk factor |
Hypogonadotropic hypogonadism 15 with anosmia, Hypogonadotropic hypogonadism 15 with anosmia |
| RS761326211 |
BRAF
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS761327787 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS761328610 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
CBL-related disorder, RASopathy |
| RS761328915 |
CPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Pulmonary hypertension, neonatal |
| RS761329565 |
POLE
|
Health Risk |
Pathogenic |
Colorectal cancer, susceptibility to |
| RS761330483 |
NBAS
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile liver failure, Infantile liver failure |
| RS761330915 |
VLDLR
|
Health Risk |
Likely pathogenic |
Cerebellar ataxia, intellectual disability |
| RS761331634 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS761332159 |
GDAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4A, Charcot-Marie-Tooth disease type 4A |
| RS761332247 |
GYS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease due to muscle and heart glycogen synthase deficiency, Glycogen storage disease due to muscle and heart glycogen synthase deficiency |
| RS761333438 |
SCN1A
|
Health Risk |
Pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS761334309 |
MRPS2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation deficiency 36, Combined oxidative phosphorylation deficiency 36 |
| RS761334406 |
ACADM
|
Health Risk |
Pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS761336234 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 13 |
| RS761336347 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS761336394 |
NAA15
|
Health Risk |
Pathogenic |
— |
| RS761336580 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761336987 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Hereditary cancer-predisposing syndrome |
| RS761340026 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761341105 |
CNGA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761341202 |
FERMT1
|
Health Risk |
Pathogenic |
— |
| RS761341365 |
LRIT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761341366 |
LRP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 17, Cenani-Lenz syndactyly syndrome |
| RS761341705 |
DNAH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761341952 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS761342219 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS761342538 |
PITPNM3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 5, Cone-rod dystrophy 5 |
| RS761342764 |
GPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
GPD1-related disorder, GPD1-related disorder |
| RS761343107 |
MRPL44
|
Health Risk |
Likely pathogenic |
Infantile hypertrophic cardiomyopathy due to MRPL44 deficiency, Infantile hypertrophic cardiomyopathy due to MRPL44 deficiency |
| RS761343609 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Neuroblastoma |
| RS761345398 |
ACE
|
Health Risk |
Likely pathogenic |
— |
| RS761345476 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |