| RS761095873 |
GFM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1, Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 |
| RS761095930 |
CYP2U1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS761096069 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS761097220 |
FARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation defect type 14, Inborn genetic diseases |
| RS761100130 |
OFD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Orofaciodigital syndrome I |
| RS761100309 |
ARSG
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome, type 4 |
| RS761101213 |
BBS10
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 10 |
| RS761101420 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS761101728 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Endometrial carcinoma |
| RS761102084 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS761102100 |
ACAD9
|
Health Risk |
Likely pathogenic |
Acyl-CoA dehydrogenase 9 deficiency, Acyl-CoA dehydrogenase 9 deficiency |
| RS761102719 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS761103593 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS761103724 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS761104090 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS761105256 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS761105413 |
SPTA1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS761105696 |
CA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteopetrosis with renal tubular acidosis, Osteopetrosis with renal tubular acidosis |
| RS761105777 |
DNAJC21
|
Health Risk |
Pathogenic |
— |
| RS761106515 |
EIF2B4
|
Health Risk |
Pathogenic |
— |
| RS761106917 |
TRAPPC9
|
Health Risk |
Likely pathogenic |
— |
| RS761108304 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS761108868 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS761109477 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS761110034 |
MCCC1
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 1 deficiency, 3-methylcrotonyl-CoA carboxylase 1 deficiency |
| RS761110882 |
GRIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant |
| RS761112550 |
RD3
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 12, Leber congenital amaurosis 12 |
| RS761114814 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761114952 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS761114963 |
TBCD
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761115271 |
CHD2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy 94, Developmental and epileptic encephalopathy 94 |
| RS761115975 |
GAMT
|
Health Risk |
Likely pathogenic |
Cerebral creatine deficiency syndrome, Deficiency of guanidinoacetate methyltransferase |
| RS761115996 |
ABCA7
|
Health Risk |
Likely pathogenic |
— |
| RS761117459 |
HEXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Sandhoff disease, Sandhoff disease |
| RS761117807 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Ehlers-Danlos syndrome |
| RS761118301 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinal dystrophy |
| RS761118747 |
LAMA3
|
Health Risk |
Likely pathogenic |
Laryngo-onycho-cutaneous syndrome, Laryngo-onycho-cutaneous syndrome |
| RS761119964 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS761120542 |
CDK13
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital heart defects, dysmorphic facial features |
| RS761121419 |
PUS7
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Intellectual developmental disorder with abnormal behavior |
| RS761121795 |
NUS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of glycosylation, type IAA |
| RS761122371 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 12 |
| RS761125486 |
COL9A2
|
Health Risk |
Pathogenic |
— |
| RS761126029 |
MGME1
|
Health Risk |
Pathogenic |
— |
| RS761126767 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS761127171 |
CHD2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy 94, Epilepsy |
| RS761127172 |
NEFH
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761127806 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
DiGeorge syndrome, DiGeorge syndrome |
| RS761129296 |
MMUT
|
Health Risk |
Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency |
| RS761129445 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS761129846 |
POGZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761129859 |
ATF6
|
Health Risk |
Pathogenic |
Achromatopsia 7, Achromatopsia 7 |
| RS761130568 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS761131048 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish type amyloidosis, Finnish type amyloidosis |
| RS761131320 |
EPRS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukodystrophy, hypomyelinating |
| RS761131376 |
LRP5
|
Health Risk |
Pathogenic/Likely pathogenic |
Exudative vitreoretinopathy 4, Retinal dystrophy |
| RS761133847 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Coffin-Siris syndrome 1 |
| RS761134229 |
PMS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Mismatch repair cancer syndrome 4 |
| RS761134985 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS761136328 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS761136347 |
SYCP3
|
Health Risk |
Pathogenic |
Spermatogenic failure 4, Spermatogenic failure 4 |
| RS761136437 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS761138317 |
GRK1
|
Health Risk |
Likely pathogenic |
Oguchi disease-2, Oguchi disease-2 |
| RS761138496 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS761140161 |
OCRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Lowe syndrome, Nephrolithiasis/nephrocalcinosis |
| RS761140414 |
DNMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory neuropathy-deafness-dementia syndrome, Hereditary sensory neuropathy-deafness-dementia syndrome |
| RS761141661 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS761142233 |
NPHP4
|
Health Risk |
Likely pathogenic |
Nephronophthisis, Senior-Loken syndrome 4 |
| RS761143874 |
AGPAT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital generalized lipodystrophy type 1, Congenital generalized lipodystrophy type 1 |
| RS76114420 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS761144879 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS761144920 |
HPS3
|
Health Risk |
Likely pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS761146008 |
MLYCD
|
Health Risk |
Pathogenic |
Deficiency of malonyl-CoA decarboxylase, Sarcoma |
| RS761146363 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS761146388 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures, Inborn genetic diseases |
| RS761147008 |
HLCS
|
Health Risk |
Conflicting classifications of pathogenicity |
Holocarboxylase synthetase deficiency, Inborn genetic diseases |
| RS761147595 |
PCARE
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS761148721 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
PTEN hamartoma tumor syndrome, Cowden syndrome 1 |
| RS761149153 |
NDUFA10
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761149240 |
SCAPER
|
Health Risk |
Likely pathogenic |
Intellectual developmental disorder and retinitis pigmentosa, IDDRP |
| RS761150081 |
HOGA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS761152033 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS761152494 |
PROM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS761154340 |
AASS
|
Health Risk |
Likely pathogenic |
Hyperlysinemia, Hyperlysinemia |
| RS761154999 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Central core myopathy |
| RS761155455 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS761155688 |
TNFRSF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
TNF receptor-associated periodic fever syndrome (TRAPS), Autoinflammatory syndrome |
| RS761155698 |
DNHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
DNHD1-related disorder, DNHD1-related disorder |
| RS761156723 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS761156912 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS761158492 |
PLVAP
|
Health Risk |
Pathogenic |
Diarrhea 10, protein-losing enteropathy type |
| RS761159697 |
XIAP
|
Health Risk |
Pathogenic |
X-linked lymphoproliferative disease due to XIAP deficiency, X-linked lymphoproliferative disease due to XIAP deficiency |
| RS761161131 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS761161412 |
F12
|
Health Risk |
Conflicting classifications of pathogenicity |
Factor XII deficiency disease, Hereditary angioedema type 3 |
| RS761162904 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS761163163 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761163530 |
ABCA4
|
Health Risk |
Likely pathogenic |
— |
| RS761164010 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 11, Usher syndrome type 1B |
| RS761164094 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS761164605 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Melanoma |