| RS761551726 |
SIK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 30 |
| RS761552446 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS761553925 |
PEPD
|
Health Risk |
Conflicting classifications of pathogenicity |
Prolidase deficiency, Prolidase deficiency |
| RS761554022 |
EPG5
|
Health Risk |
Pathogenic |
Vici syndrome, Vici syndrome |
| RS761554206 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS761554381 |
RGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 44, Retinitis pigmentosa 44 |
| RS761554853 |
CNGA3
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Achromatopsia 2 |
| RS761555167 |
ARSA
|
Health Risk |
Pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS761557390 |
ABCA12
|
Health Risk |
Pathogenic |
— |
| RS761558985 |
NAGS
|
Health Risk |
Pathogenic/Likely pathogenic |
Hyperammonemia, type III |
| RS761559887 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS761560224 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS761562076 |
NOTCH1
|
Health Risk |
Pathogenic |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS761562615 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS761563364 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761564262 |
XRCC1
|
Health Risk |
Likely pathogenic |
Spinocerebellar ataxia, autosomal recessive 26 |
| RS761564635 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Intrauterine growth retardation |
| RS761565265 |
ACAD9
|
Health Risk |
Conflicting classifications of pathogenicity |
Acyl-CoA dehydrogenase 9 deficiency, Inborn genetic diseases |
| RS761565516 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-hypotonia-spasticity-sleep disorder syndrome, Intellectual disability-hypotonia-spasticity-sleep disorder syndrome |
| RS761567176 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS761568836 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS761569930 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis 2 |
| RS761572391 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761572907 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS761573352 |
ACSF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS761574063 |
PROS1
|
Health Risk |
Likely pathogenic |
Protein S deficiency disease, Protein S deficiency disease |
| RS761575154 |
SALL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Townes syndrome, Townes syndrome |
| RS761575210 |
CYP2U1
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 56, Hereditary spastic paraplegia 56 |
| RS761575295 |
ATP8B1
|
Health Risk |
Pathogenic |
Benign recurrent intrahepatic cholestasis type 1, Benign recurrent intrahepatic cholestasis type 1 |
| RS761575760 |
PHF21A
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures, Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures |
| RS761575973 |
PLCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 3 |
| RS761576251 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS761576315 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS761577170 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS761577958 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS761578558 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS761579423 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS761579543 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS761580028 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS761580972 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS761581335 |
LOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS761581720 |
CHRNG
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive multiple pterygium syndrome, Lethal multiple pterygium syndrome |
| RS761581941 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS761582251 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 5 |
| RS761583890 |
JAK3
|
Health Risk |
Pathogenic/Likely pathogenic |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, Severe combined immunodeficiency disease |
| RS761584017 |
RAPSN
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome 11, Fetal akinesia deformation sequence 1 |
| RS761584493 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761584506 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS761585108 |
KCNH2
|
Health Risk |
Pathogenic |
Long QT syndrome, Long QT syndrome |
| RS761585117 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Lung cancer |
| RS761585621 |
NPHP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, NPHP3-related Meckel-like syndrome |
| RS761588725 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761589107 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS761589376 |
RAD51D
|
Health Risk |
Pathogenic/Likely pathogenic |
Breast-ovarian cancer, familial |
| RS761591000 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS761591158 |
JPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS761592042 |
TEX14
|
Health Risk |
Pathogenic |
Spermatogenic failure 23, Spermatogenic failure 23 |
| RS761592349 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Familial adenomatous polyposis 1 |
| RS761592620 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761592860 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS761594079 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS761594217 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761595544 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS761596254 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial septal defect 7, Cardiovascular phenotype |
| RS761596436 |
CNTNAP2
|
Health Risk |
Pathogenic |
Cortical dysplasia-focal epilepsy syndrome, Cortical dysplasia-focal epilepsy syndrome |
| RS761596789 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS761597986 |
RTTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761599964 |
ACTA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS761600175 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Vesicoureteral reflux 8, Ehlers-Danlos syndrome due to tenascin-X deficiency |
| RS761600715 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS761601545 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS761602495 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS761602649 |
HNRNPU
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 54 |
| RS761602674 |
PRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS761603858 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Brittle cornea syndrome 1, Cardiovascular phenotype |
| RS761604406 |
DOLK
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS761605711 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS761605754 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic right ventricular dysplasia 8 |
| RS761606317 |
ARSA
|
Health Risk |
Pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS761607612 |
SGSH
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS761608162 |
TYMP
|
Health Risk |
Pathogenic |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS761609284 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Malignant tumor of urinary bladder |
| RS761612652 |
INPP5K
|
Health Risk |
Pathogenic |
Congenital muscular dystrophy with cataracts and intellectual disability, Congenital muscular dystrophy with cataracts and intellectual disability |
| RS761612832 |
PAX8
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypothyroidism, congenital |
| RS761613652 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Cardiomyopathy |
| RS761613739 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS761614356 |
SYNJ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 53 |
| RS761614407 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761615413 |
SDHD
|
Health Risk |
Pathogenic |
Paragangliomas with sensorineural hearing loss, Carney-Stratakis syndrome |
| RS761616685 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS761616770 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS761616995 |
KPTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrocephaly-developmental delay syndrome, Macrocephaly-developmental delay syndrome |
| RS761617432 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS761617724 |
SPAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia |
| RS761618860 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS761619279 |
CCDC40
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 15 |
| RS761619655 |
C2
|
Health Risk |
Pathogenic |
— |
| RS761619791 |
PDE6B
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS761619802 |
QDPR
|
Health Risk |
Pathogenic |
Dihydropteridine reductase deficiency, Colorectal cancer |
| RS761620701 |
MLC1
|
Health Risk |
Pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts 1 |