| RS756008578 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS756010097 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756010661 |
SLC6A19
|
Health Risk |
Conflicting classifications of pathogenicity |
High myopia, Hyperglycinuria |
| RS756011865 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to CREBBP mutations, Inborn genetic diseases |
| RS756012779 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Early-onset myopathy with fatal cardiomyopathy |
| RS756013171 |
VPS13B
|
Health Risk |
Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS756013406 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS756013479 |
NADK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive encephalopathy with leukodystrophy due to DECR deficiency, Progressive encephalopathy with leukodystrophy due to DECR deficiency |
| RS756013694 |
RPS6KA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Coffin-Lowry syndrome, Intellectual disability |
| RS756015202 |
DOK7
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 10, Congenital myasthenic syndrome 10 |
| RS756016704 |
LIPA
|
Health Risk |
Pathogenic |
Lysosomal acid lipase deficiency, Wolman disease |
| RS756016910 |
TSHR
|
Health Risk |
Pathogenic |
Hypothyroidism due to TSH receptor mutations, Hypothyroidism due to TSH receptor mutations |
| RS756017020 |
TRIOBP
|
Health Risk |
Conflicting classifications of pathogenicity |
TRIOBP-related disorder, TRIOBP-related disorder |
| RS756017412 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS756017426 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS756018135 |
FANCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS756018344 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS756018487 |
MTHFR
|
Health Risk |
Pathogenic |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, Homocystinuria due to methylene tetrahydrofolate reductase deficiency |
| RS756018704 |
RAI1
|
Health Risk |
Pathogenic |
— |
| RS756018749 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS756019325 |
SLC26A4
|
Health Risk |
Pathogenic |
— |
| RS756020699 |
BAG3
|
Health Risk |
Pathogenic |
Myofibrillar myopathy 6, Dilated cardiomyopathy 1HH |
| RS756020849 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS756021170 |
CPS1
|
Health Risk |
Likely pathogenic |
Congenital hyperammonemia, type I |
| RS756021330 |
PCLO
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756021768 |
MARS1
|
Health Risk |
Pathogenic |
Pulmonary alveolar proteinosis, Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency |
| RS756022224 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS756022347 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, NSD1-related disorder |
| RS756023006 |
FANCA
|
Health Risk |
Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS756023124 |
NEU1
|
Health Risk |
Pathogenic |
— |
| RS756023239 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, normal intelligence and immunodeficiency |
| RS75602337 |
WDR35
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 7 with or without polydactyly, Cranioectodermal dysplasia 2 |
| RS756023441 |
PDHX
|
Health Risk |
Likely pathogenic |
Pyruvate dehydrogenase E3-binding protein deficiency, Pyruvate dehydrogenase E3-binding protein deficiency |
| RS756023893 |
PEX3
|
Health Risk |
Likely pathogenic |
— |
| RS756024033 |
TUBB2B
|
Health Risk |
Likely pathogenic |
— |
| RS756024445 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756025227 |
VPS13D
|
Health Risk |
Pathogenic |
Autosomal recessive cerebellar ataxia-saccadic intrusion syndrome, Autosomal recessive cerebellar ataxia-saccadic intrusion syndrome |
| RS756025941 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS756026742 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS756026847 |
CLASP1;CLASP1-AS1;RNU4ATAC
|
Health Risk |
Conflicting classifications of pathogenicity |
Roifman syndrome, Osteodysplastic primordial dwarfism |
| RS756029120 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS756029160 |
DNAAF11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 19, Primary ciliary dyskinesia 19 |
| RS756029240 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS756029520 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, autosomal dominant |
| RS756030149 |
LHFPL5
|
Health Risk |
Likely pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS756031031 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pulmonary alveolar proteinosis, ABCA3-related disorder |
| RS756031857 |
SMPD1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type A |
| RS756032160 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS756032457 |
USH1C
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 18A, Autosomal recessive nonsyndromic hearing loss 18A |
| RS756035074 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS756036451 |
CHST6
|
Health Risk |
Pathogenic/Likely pathogenic |
Macular corneal dystrophy, Macular corneal dystrophy |
| RS756038056 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS756038490 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS756039188 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS756039521 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS756040251 |
HEXA
|
Health Risk |
Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS756040379 |
MRE11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia-like disorder |
| RS756040945 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS756041561 |
ASAH1
|
Health Risk |
Pathogenic |
— |
| RS756041768 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS756042084 |
SI
|
Health Risk |
Conflicting classifications of pathogenicity |
Sucrase-isomaltase deficiency, Sucrase-isomaltase deficiency |
| RS756042888 |
ZFYVE26
|
Health Risk |
Pathogenic/Likely pathogenic |
Spastic paraplegia, Hereditary spastic paraplegia 15 |
| RS756043669 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS756044034 |
SMARCA4
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal dominant 16 |
| RS756044431 |
TUB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756044745 |
GUCY2D
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 6, Leber congenital amaurosis 1 |
| RS756045079 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS756045177 |
NGLY1
|
Health Risk |
Likely pathogenic |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation |
| RS756045492 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS756048549 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS756049331 |
TBX5
|
Health Risk |
Pathogenic |
Holt-Oram syndrome, Holt-Oram syndrome |
| RS756050324 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756050702 |
ERCC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group Q, Xeroderma pigmentosum |
| RS756051157 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS756052150 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Cardiovascular phenotype |
| RS756052603 |
BCKDHA
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Familial cancer of breast |
| RS756053197 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS756054017 |
CDON
|
Health Risk |
Conflicting classifications of pathogenicity |
Holoprosencephaly 11, Inborn genetic diseases |
| RS756054473 |
KLHL17
|
Health Risk |
Likely pathogenic |
Esophageal atresia/tracheoesophageal fistula, Esophageal atresia/tracheoesophageal fistula |
| RS756055115 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS756055892 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 4 |
| RS756056158 |
TRRAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756056441 |
SPEG
|
Health Risk |
Likely pathogenic |
SPEG-related congenital myopathy, SPEG-related congenital myopathy |
| RS756057922 |
SLC12A1
|
Health Risk |
Pathogenic |
Bartter disease type 1, Bartter disease type 1 |
| RS756058789 |
LAMC3
|
Health Risk |
Pathogenic |
— |
| RS756059211 |
ZMIZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756060769 |
MIPEP
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal left ventricular non-compaction-seizures-hypotonia-cataract-developmental delay syndrome, Lethal left ventricular non-compaction-seizures-hypotonia-cataract-developmental delay syndrome |
| RS756061536 |
BBS12
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 12, Bardet-Biedl syndrome |
| RS756061989 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency, EP300-related disorder |
| RS756062421 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756062534 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS756062872 |
GATAD2B
|
Health Risk |
Likely pathogenic |
Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome, Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome |
| RS756062969 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated Nonsyndromic Congenital Heart Disease, Alagille syndrome due to a JAG1 point mutation |
| RS756064266 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS756064750 |
CPAMD8
|
Health Risk |
Pathogenic |
Anterior segment dysgenesis 8, Anterior segment dysgenesis 8 |
| RS756065296 |
EFEMP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Glaucoma 1 |
| RS756065515 |
SLC16A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS756065709 |
SERAC1
|
Health Risk |
Pathogenic |
3-methylglutaconic aciduria with deafness, encephalopathy |
| RS756065878 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS756066219 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |