| RS756067217 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756068066 |
PSTPIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyogenic arthritis-pyoderma gangrenosum-acne syndrome, Pyogenic arthritis-pyoderma gangrenosum-acne syndrome |
| RS756068705 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Porokeratosis 3, disseminated superficial actinic type |
| RS756069384 |
PTCH1
|
Health Risk |
Likely pathogenic |
Rhabdomyosarcoma, Rhabdomyosarcoma |
| RS756069405 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS756069599 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS756070988 |
COL4A5
|
Health Risk |
Likely pathogenic |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS756071120 |
RAB27A
|
Health Risk |
Pathogenic |
Griscelli syndrome type 2, See cases |
| RS756072030 |
POLR1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Treacher Collins syndrome 3, Hypomyelinating leukodystrophy 11 |
| RS756073260 |
TWNK
|
Health Risk |
Likely pathogenic |
Auditory neuropathy, Auditory neuropathy |
| RS756074454 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHARGE syndrome |
| RS756075225 |
COMP
|
Health Risk |
Conflicting classifications of pathogenicity |
COMP-related disorder, COMP-related disorder |
| RS756075877 |
ANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spherocytosis, Hereditary spherocytosis type 1 |
| RS756076960 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Pendred syndrome, Pendred syndrome |
| RS756077143 |
CYP26B1
|
Health Risk |
Likely pathogenic |
Lethal occipital encephalocele-skeletal dysplasia syndrome, Lethal occipital encephalocele-skeletal dysplasia syndrome |
| RS756078257 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS756078681 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Drash syndrome, Frasier syndrome |
| RS756080695 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS756080885 |
ARG1
|
Health Risk |
Pathogenic |
Arginase deficiency, Arginase deficiency |
| RS756081560 |
ADAMTSL4
|
Health Risk |
Likely pathogenic |
— |
| RS756082859 |
MCM3AP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756083426 |
NOVA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756083696 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS756084170 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS756085990 |
NFU1
|
Health Risk |
Pathogenic |
Multiple mitochondrial dysfunctions syndrome 1, Familial cancer of breast |
| RS756087583 |
MCOLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucolipidosis type IV, Mucolipidosis type IV |
| RS756087785 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS756088593 |
SI
|
Health Risk |
Pathogenic |
— |
| RS756090222 |
ANKS6
|
Health Risk |
Pathogenic |
Nephronophthisis 16, Nephronophthisis 16 |
| RS756091180 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS756093689 |
GNPTG
|
Health Risk |
Pathogenic |
— |
| RS756094298 |
EGLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrocytosis, familial |
| RS756095042 |
CDHR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 15, Inborn genetic diseases |
| RS756096368 |
VPS13A
|
Health Risk |
Pathogenic |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS756096769 |
RTTN
|
Health Risk |
Likely pathogenic |
Microcephalic primordial dwarfism due to RTTN deficiency, Microcephalic primordial dwarfism due to RTTN deficiency |
| RS756098102 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 3, Jeune thoracic dystrophy |
| RS756098317 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS756099573 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756099600 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS756100330 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Ullrich congenital muscular dystrophy 2 |
| RS756101133 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS756101515 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 6, Pontoneocerebellar hypoplasia |
| RS756101924 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756102768 |
MKS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 13, Meckel syndrome |
| RS756103019 |
SPG11
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 11, Amyotrophic lateral sclerosis type 5 |
| RS756103623 |
PLAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756103727 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756103866 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
8 conditions, 8 conditions |
| RS756104818 |
SAMD9L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756105620 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS756105948 |
PRMT9
|
Health Risk |
Pathogenic |
Neurodevelopmental abnormality, Neurodevelopmental abnormality |
| RS756108143 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Lynch syndrome 5 |
| RS756109661 |
LPIN2
|
Health Risk |
Likely pathogenic |
Majeed syndrome, Majeed syndrome |
| RS756110037 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa 25 |
| RS756111113 |
NPHP4
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Kidney disorder |
| RS756112023 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS756112245 |
ELANE
|
Health Risk |
Conflicting classifications of pathogenicity |
Cyclical neutropenia, Neutropenia |
| RS756112449 |
CTSD
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 10, Neuronal ceroid lipofuscinosis 10 |
| RS756114192 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS756114856 |
NEFL
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2E, Inborn genetic diseases |
| RS756115857 |
DNAH11
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756116434 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
WFS1-Related Spectrum Disorders, Autosomal dominant nonsyndromic hearing loss 6 |
| RS756116550 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS756116554 |
SCN9A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS756117435 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS756117745 |
KIF7
|
Health Risk |
Conflicting classifications of pathogenicity |
Acrocallosal syndrome, Acrocallosal syndrome |
| RS756118312 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS756119154 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS756119359 |
FZD4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756120041 |
SOX10
|
Health Risk |
Pathogenic |
Waardenburg syndrome type 4C, Waardenburg syndrome type 4C |
| RS756121249 |
GDAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4A, Inborn genetic diseases |
| RS756121992 |
EIF2B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS756122519 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS756122685 |
CACNA2D4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756122840 |
REN
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal tubular dysgenesis, Familial juvenile hyperuricemic nephropathy type 2 |
| RS756124960 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS756125441 |
TF
|
Health Risk |
Conflicting classifications of pathogenicity |
Atransferrinemia, Atransferrinemia |
| RS756125442 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, type 4 |
| RS756125516 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, 15 conditions |
| RS756126843 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Inborn genetic diseases |
| RS756127631 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cognitive impairment with or without cerebellar ataxia, Seizures |
| RS756127972 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome |
| RS756128065 |
VPS13C
|
Health Risk |
Likely pathogenic |
— |
| RS756128531 |
RBP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS756128568 |
RMRP
|
Health Risk |
Conflicting classifications of pathogenicity |
Anauxetic dysplasia, Anauxetic dysplasia |
| RS756128712 |
DPH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Developmental delay with short stature, dysmorphic facial features |
| RS756130118 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS756130763 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS756131136 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS756131313 |
LAMA2
|
Health Risk |
Pathogenic |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS756131416 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS756131787 |
IDUA
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-I-H/S |
| RS756131845 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS756133268 |
CHST3
|
Health Risk |
Pathogenic |
Spondyloepiphyseal dysplasia with congenital joint dislocations, Spondyloepiphyseal dysplasia with congenital joint dislocations |
| RS756133651 |
COL4A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive Alport syndrome, Benign familial hematuria |
| RS756134134 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, COL7A1-related disorder |
| RS756134516 |
SPG11
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS756134541 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756134838 |
HGD
|
Health Risk |
Pathogenic |
Alkaptonuria, Alkaptonuria |
| RS756135168 |
CYP17A1
|
Health Risk |
Pathogenic |
Deficiency of steroid 17-alpha-monooxygenase, 17-alpha-hydroxylase/17 |