| RS756198538 |
ASPA
|
Health Risk |
Pathogenic |
Spongy degeneration of central nervous system, Canavan Disease |
| RS756199090 |
TYRP1
|
Health Risk |
Pathogenic |
— |
| RS756199349 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS756201106 |
CFI
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 13, Atypical hemolytic-uremic syndrome with I factor anomaly |
| RS756201576 |
LRRIQ3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756202530 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, DICER1-related tumor predisposition |
| RS756203141 |
USH2A
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS756203389 |
CSF2RA
|
Health Risk |
Pathogenic |
Surfactant metabolism dysfunction, pulmonary |
| RS756203775 |
FRMD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756204684 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Late-infantile neuronal ceroid lipofuscinosis |
| RS756204866 |
EXOSC2
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa-hearing loss-premature aging-short stature-facial dysmorphism syndrome, Retinitis pigmentosa-hearing loss-premature aging-short stature-facial dysmorphism syndrome |
| RS756205069 |
AFG3L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756205397 |
PYGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type VI |
| RS756205995 |
CAPN1
|
Health Risk |
Pathogenic |
Autosomal recessive spastic paraplegia type 76, Autosomal recessive spastic paraplegia type 76 |
| RS756206533 |
CFTR
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS756206757 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS756206942 |
NDE1
|
Health Risk |
Pathogenic |
Lissencephaly 4, NDE1-related microhydranencephaly |
| RS756207677 |
CYFIP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 65 |
| RS756209187 |
APOB
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypobetalipoproteinemia, Familial hypobetalipoproteinemia 1 |
| RS756209197 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS756209340 |
PRDM16
|
Health Risk |
Conflicting classifications of pathogenicity |
Left ventricular noncompaction 8, Inborn genetic diseases |
| RS756209410 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS756209420 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS756210458 |
ADSL
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe global developmental delay, Difficulty standing |
| RS756211242 |
KAT8
|
Health Risk |
Likely pathogenic |
Li-Ghorbani-Weisz-Hubshman syndrome, Li-Ghorbani-Weisz-Hubshman syndrome |
| RS756211633 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS756212622 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS756213406 |
CHRNE
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome, Congenital myasthenic syndrome 4A |
| RS756214140 |
TBL1XR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pierpont syndrome, Pierpont syndrome |
| RS756215705 |
HPS4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 4, Hermansky-Pudlak syndrome 4 |
| RS756216163 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756216318 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS756216566 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS756217590 |
COL7A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Recessive dystrophic epidermolysis bullosa, Pretibial dystrophic epidermolysis bullosa |
| RS756217962 |
AHI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 3 |
| RS75621801 |
MTTP
|
Health Risk |
Pathogenic |
— |
| RS756218448 |
MCCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, 3-methylcrotonyl-CoA carboxylase 2 deficiency |
| RS756219310 |
CFTR
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystic fibrosis, Bronchiectasis with or without elevated sweat chloride 1 |
| RS756219617 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS756220860 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
Benign recurrent intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS756221585 |
MMAA
|
Health Risk |
Pathogenic |
Methylmalonic aciduria, cblA type |
| RS756221917 |
HERC2
|
Health Risk |
Pathogenic |
Developmental delay with autism spectrum disorder and gait instability, Developmental delay with autism spectrum disorder and gait instability |
| RS756221937 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS75622274 |
ITGA2B
|
Health Risk |
Pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia 1 |
| RS756223600 |
COL18A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Knobloch syndrome 1 |
| RS756224211 |
SMARCA4
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS756225038 |
ZNF142
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with impaired speech and hyperkinetic movements, Inborn genetic diseases |
| RS756225250 |
ZIC2
|
Health Risk |
Pathogenic |
Holoprosencephaly 5, Holoprosencephaly 5 |
| RS756225251 |
GNPTG
|
Health Risk |
Pathogenic |
GNPTG-mucolipidosis, Rod-cone dystrophy |
| RS756225459 |
TG
|
Health Risk |
Pathogenic |
— |
| RS756225547 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756225782 |
MMUT
|
Health Risk |
Likely pathogenic |
— |
| RS756227025 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS756227982 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, COL3A1-related disorder |
| RS756228059 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS756229364 |
MERTK
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 38, Retinitis pigmentosa 38 |
| RS756230327 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS756230727 |
CA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, CA4-related disorder |
| RS756231749 |
COL4A3
|
Health Risk |
Pathogenic |
Alport syndrome, Autosomal dominant Alport syndrome |
| RS756231829 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1, Usher syndrome type 1D |
| RS756232002 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS756232510 |
TMPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Loeys-Dietz syndrome 2, Loeys-Dietz syndrome 2 |
| RS756232889 |
MC4R
|
Health Risk |
Pathogenic |
Obesity, Obesity |
| RS756233241 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Li-Fraumeni syndrome, Hereditary cancer-predisposing syndrome |
| RS756233245 |
MCM8
|
Health Risk |
Pathogenic |
— |
| RS756233808 |
DNAAF5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756233978 |
OTOGL
|
Health Risk |
Likely pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS756235051 |
GRK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oguchi disease-2, Retinal dystrophy |
| RS756235299 |
ETHE1
|
Health Risk |
Likely pathogenic |
Ethylmalonic encephalopathy, Ethylmalonic encephalopathy |
| RS756235547 |
CCDC39
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 14 |
| RS756236271 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital multicore myopathy with external ophthalmoplegia, Malignant hyperthermia |
| RS756236683 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756236720 |
CTRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS756236810 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756236917 |
ALG1
|
Health Risk |
Pathogenic |
ALG1-congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |
| RS756237962 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS756238158 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Becker muscular dystrophy, Duchenne muscular dystrophy |
| RS756238324 |
PRKCSH
|
Health Risk |
Likely pathogenic |
Polycystic liver disease 1, Polycystic liver disease 1 |
| RS756238700 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS756238772 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS756239167 |
TK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome, myopathic form |
| RS756239195 |
CNGB1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 45, Retinitis pigmentosa 45 |
| RS756239722 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 10, Cardiovascular phenotype |
| RS756239767 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Cervical cancer |
| RS756242095 |
HPD
|
Health Risk |
Conflicting classifications of pathogenicity |
Hawkinsinuria, Tyrosinemia type III |
| RS756243022 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS756243240 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Inborn genetic diseases |
| RS756244380 |
NPHS1
|
Health Risk |
Likely pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS756246229 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Facial dysmorphism-immunodeficiency-livedo-short stature syndrome |
| RS756247881 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
CODAS syndrome, CODAS syndrome |
| RS756249036 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS756250205 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS756250298 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS756250449 |
CTSK
|
Health Risk |
Pathogenic |
Pyknodysostosis, Pyknodysostosis |
| RS756251613 |
GCK
|
Health Risk |
Likely pathogenic |
Monogenic diabetes, Monogenic diabetes |
| RS756251887 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS756252214 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Wolfram syndrome 1, WFS1-related disorder |
| RS756252418 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hemorrhagic telangiectasia, Hereditary hemorrhagic telangiectasia |
| RS756252903 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS756254299 |
PHKA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXa1, Inborn genetic diseases |