| RS756390450 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia 42, early-onset |
| RS756390955 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756391068 |
GABBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS75639119 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS756392442 |
ANKRD1
|
Health Risk |
Conflicting classifications of pathogenicity |
ANKRD1-related dilated cardiomyopathy, Cardiovascular phenotype |
| RS756393096 |
NCF2
|
Health Risk |
Pathogenic |
Granulomatous disease, chronic |
| RS756393374 |
COL27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756394364 |
ALPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypophosphatasia, Hypophosphatasia |
| RS756394857 |
GTPBP3
|
Health Risk |
Pathogenic/Likely pathogenic |
See cases, See cases |
| RS756395915 |
ATP8B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive familial intrahepatic cholestasis, Benign recurrent intrahepatic cholestasis type 1 |
| RS756396172 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Atelosteogenesis type I, Atelosteogenesis type I |
| RS756396993 |
TTC7A
|
Health Risk |
Likely pathogenic |
Multiple gastrointestinal atresias, Multiple gastrointestinal atresias |
| RS756398214 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS756398627 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS756398636 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS756399499 |
CORIN
|
Health Risk |
Pathogenic |
Atrial fibrillation, Cardiomyopathy |
| RS756399613 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Noonan syndrome 9 |
| RS756400234 |
BRAF
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS756401086 |
NALCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756402483 |
TCTN1
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS756402556 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1, PCDH15-related disorder |
| RS756403702 |
GLB1
|
Health Risk |
Conflicting classifications of pathogenicity |
GM1 gangliosidosis, Mucopolysaccharidosis |
| RS756405261 |
SRD5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency, 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency |
| RS756405444 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS756406920 |
ARSG
|
Health Risk |
Pathogenic |
— |
| RS756407279 |
RDX
|
Health Risk |
Likely pathogenic |
Nonsyndromic genetic hearing loss, Nonsyndromic genetic hearing loss |
| RS756407851 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Dilated cardiomyopathy 1AA |
| RS756408696 |
MYO18B
|
Health Risk |
Pathogenic/Likely pathogenic |
Klippel-Feil anomaly-myopathy-facial dysmorphism syndrome, Klippel-Feil anomaly-myopathy-facial dysmorphism syndrome |
| RS756410019 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS756411505 |
ALPK3
|
Health Risk |
Pathogenic |
— |
| RS756411508 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS756413692 |
MMACHC
|
Health Risk |
Pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS756414069 |
PEPD
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756414393 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Febrile seizures |
| RS756414485 |
PCDH19
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS756414548 |
MMAB
|
Health Risk |
Pathogenic |
Methylmalonic aciduria, cblB type |
| RS756414710 |
PCCB
|
Health Risk |
Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS756416171 |
CPLANE1
|
Health Risk |
Pathogenic |
— |
| RS756418235 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Adult hypophosphatasia, Childhood hypophosphatasia |
| RS756418963 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Elliptocytosis 2, Pyropoikilocytosis |
| RS756419208 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS756419434 |
DEAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-epilepsy-extrapyramidal syndrome, Intellectual disability-epilepsy-extrapyramidal syndrome |
| RS756419705 |
ABCB4
|
Health Risk |
Pathogenic |
Progressive familial intrahepatic cholestasis type 3, Progressive familial intrahepatic cholestasis type 3 |
| RS756420203 |
ERCC5
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebrooculofacioskeletal syndrome 3, Xeroderma pigmentosum |
| RS756420276 |
MADD
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with dysmorphic facies, impaired speech |
| RS756420301 |
HGSNAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS756420413 |
FANCL
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group L, Fanconi anemia |
| RS756420858 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS756421370 |
MECR
|
Health Risk |
Pathogenic/Likely pathogenic |
Dystonia, childhood-onset |
| RS756423026 |
CSPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 21, Inborn genetic diseases |
| RS756423093 |
KIZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS756423843 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Inborn genetic diseases |
| RS756424912 |
EVC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS756427418 |
MAN2C1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of deglycosylation 2, Congenital disorder of deglycosylation 2 |
| RS756427983 |
CUBN
|
Health Risk |
Likely pathogenic |
Imerslund-Grasbeck syndrome, Proteinuria |
| RS756429763 |
WIPI2
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with short stature and variable skeletal anomalies, Intellectual developmental disorder with short stature and variable skeletal anomalies |
| RS756430359 |
DNAAF3
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 2 |
| RS756431692 |
MCM3AP
|
Health Risk |
Pathogenic |
Peripheral neuropathy, autosomal recessive |
| RS756432435 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Orofaciodigital syndrome type 6, Joubert syndrome 17 |
| RS756432794 |
TMPRSS3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 8, Autosomal recessive nonsyndromic hearing loss 8 |
| RS756432879 |
LAMC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Thyroid cancer |
| RS756433029 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary dilated cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS756433074 |
HPS1
|
Health Risk |
Pathogenic |
— |
| RS756433832 |
HADHA
|
Health Risk |
Likely pathogenic |
— |
| RS756433996 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS756434709 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Adams-Oliver syndrome 5 |
| RS756434860 |
RECQL
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS756434927 |
SCNN1A
|
Health Risk |
Pathogenic |
Pseudohypoaldosteronism, type IB1 |
| RS756435344 |
CPLANE1
|
Health Risk |
Likely pathogenic |
— |
| RS756435572 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS756436580 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS756437332 |
AGXT
|
Health Risk |
Likely pathogenic |
Primary hyperoxaluria, type I |
| RS756437904 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS756438139 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS756440792 |
MCOLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Mucolipidosis type IV |
| RS756442272 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS756442818 |
NDUFAF7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756443059 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS756444637 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS756444933 |
SPAG1
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia 28 |
| RS756446204 |
GAN
|
Health Risk |
Pathogenic |
Giant axonal neuropathy 1, Giant axonal neuropathy 1 |
| RS756446770 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756447715 |
CARMIL2
|
Health Risk |
Pathogenic |
— |
| RS756448158 |
ACP5
|
Health Risk |
Pathogenic |
Spondyloenchondrodysplasia with immune dysregulation, Spondyloenchondrodysplasia with immune dysregulation |
| RS756448789 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS756449511 |
CEL
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 8, Maturity-onset diabetes of the young type 8 |
| RS756449736 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, NPHP4-related disorder |
| RS756449737 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS756449782 |
CUBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Imerslund-Grasbeck syndrome, Inborn genetic diseases |
| RS756450018 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS756450204 |
NSUN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 5 |
| RS756450772 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS756451802 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS756452107 |
CD2AP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756453245 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS756454038 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756455049 |
ASAH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Farber lipogranulomatosis, Farber lipogranulomatosis |
| RS756455152 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756455658 |
CDON
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Holoprosencephaly 11 |
| RS7564566 |
RAB3GAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Warburg micro syndrome 1, Warburg micro syndrome 1 |