| RS756574089 |
HDAC4
|
Health Risk |
Likely pathogenic |
— |
| RS756575126 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic right ventricular dysplasia 5 |
| RS756575234 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS756575833 |
GLB1
|
Health Risk |
Likely pathogenic |
GM1 gangliosidosis, Mucopolysaccharidosis |
| RS756575861 |
KIAA1549
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756581500 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS756581886 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Polydactyly, Greig cephalopolysyndactyly syndrome |
| RS756582306 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, Inborn genetic diseases |
| RS756582449 |
SLITRK3
|
Health Risk |
Pathogenic |
Intellectual disability, Intellectual disability |
| RS756582576 |
COL4A6
|
Health Risk |
Conflicting classifications of pathogenicity |
COL4A6-related disorder, COL4A6-related disorder |
| RS756584594 |
TCOF1
|
Health Risk |
Conflicting classifications of pathogenicity |
TCOF1-related disorder, Treacher Collins syndrome 1 |
| RS756585755 |
PJVK
|
Health Risk |
Pathogenic |
— |
| RS756586058 |
FGD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Aarskog syndrome, FGD1-related disorder |
| RS756587349 |
LAMC3
|
Health Risk |
Likely pathogenic |
— |
| RS756587384 |
ACADSB
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of 2-methylbutyryl-CoA dehydrogenase, See cases |
| RS756588136 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756589820 |
COQ8A
|
Health Risk |
Pathogenic |
— |
| RS756590256 |
FANCL
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group L, Fanconi anemia complementation group L |
| RS756590471 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS756591718 |
PNPLA6
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS756592483 |
PHKB
|
Health Risk |
Pathogenic |
PHKB-related disorder, PHKB-related disorder |
| RS756593088 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital multicore myopathy with external ophthalmoplegia, Malignant hyperthermia |
| RS756594069 |
ARHGEF10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756594449 |
ACTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS756595568 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder, ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder |
| RS756597098 |
SACS
|
Health Risk |
Likely pathogenic |
Charlevoix-Saguenay spastic ataxia, Charlevoix-Saguenay spastic ataxia |
| RS756597120 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS756597598 |
GJB6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hidrotic ectodermal dysplasia syndrome, Autosomal dominant nonsyndromic hearing loss 3B |
| RS756599740 |
SALL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Townes syndrome, Townes syndrome |
| RS756599931 |
ACSF3
|
Health Risk |
Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS756600903 |
TRMU
|
Health Risk |
Likely pathogenic |
Aminoglycoside-induced deafness, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS756601658 |
AP3D1
|
Health Risk |
Conflicting classifications of pathogenicity |
AP3D1-related disorder, AP3D1-related disorder |
| RS756602466 |
CCDC40
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 15, Primary ciliary dyskinesia |
| RS756602672 |
RNF170
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant sensory ataxia 1, Spastic paraplegia 85 |
| RS756604268 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS756604557 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 9 |
| RS756605558 |
FLG
|
Health Risk |
Pathogenic |
— |
| RS756605964 |
ROBO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756606180 |
ALG1
|
Health Risk |
Likely pathogenic |
ALG1-congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |
| RS756606586 |
SH3BP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibrous dysplasia of jaw, Inborn genetic diseases |
| RS756606635 |
STRC
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 16, Autosomal recessive nonsyndromic hearing loss 16 |
| RS756607245 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS756607591 |
HSD3B2
|
Health Risk |
Pathogenic |
3 beta-Hydroxysteroid dehydrogenase deficiency, Congenital adrenal hyperplasia |
| RS756607995 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS756608508 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS756609752 |
PGAP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, autosomal recessive 42 |
| RS756609768 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Complex neurodevelopmental disorder, Early-infantile DEE |
| RS756610221 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756611351 |
SZT2
|
Health Risk |
Pathogenic |
— |
| RS756611519 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Perry syndrome, Neuronopathy |
| RS756611897 |
HPS3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS756612643 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS756613387 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS756614404 |
DNAJB2
|
Health Risk |
Pathogenic |
Neuronopathy, distal hereditary motor |
| RS756614581 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS756614749 |
CUBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Proteinuria, chronic benign |
| RS756614796 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS756615692 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS756615930 |
ZC4H2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756616242 |
KDM5B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS756616538 |
DNAH8
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756616712 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS756616792 |
DNAJC19
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria type 5, 3-methylglutaconic aciduria type 5 |
| RS756617788 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS756618692 |
EIF2AK3
|
Health Risk |
Conflicting classifications of pathogenicity |
EIF2AK3-related disorder, Inborn genetic diseases |
| RS756621896 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS756622196 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS756622578 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756623054 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
RAI1-related disorder, RAI1-related disorder |
| RS756623509 |
USH2A
|
Health Risk |
Pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS756623639 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS756623659 |
AGRN
|
Health Risk |
Likely pathogenic |
Congenital myasthenic syndrome, Congenital myasthenic syndrome 8 |
| RS756624928 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, Idiopathic Pulmonary Fibrosis |
| RS756625074 |
SZT2
|
Health Risk |
Likely pathogenic |
— |
| RS756626190 |
FLG
|
Health Risk |
Pathogenic |
— |
| RS756626295 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa with pyloric atresia, Junctional epidermolysis bullosa with pyloric atresia |
| RS756630156 |
ERCC2
|
Health Risk |
Pathogenic |
Trichothiodystrophy 1, photosensitive |
| RS756630815 |
AKR1D1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756631085 |
IGF2R
|
Health Risk |
Likely pathogenic |
Premature ovarian failure, Premature ovarian failure |
| RS756632286 |
G6PC1
|
Health Risk |
Likely pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS756632517 |
BBS10
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Bardet-Biedl syndrome |
| RS756632601 |
NDUFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Mitochondrial complex I deficiency |
| RS756632688 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Polyps |
| RS756632799 |
PIGT
|
Health Risk |
Pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 3, Multiple congenital anomalies-hypotonia-seizures syndrome 3 |
| RS756632960 |
MSH3
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 4 |
| RS756635283 |
SIX2
|
Health Risk |
Likely pathogenic |
— |
| RS756636036 |
ROBO4
|
Health Risk |
risk factor |
Congenital diaphragmatic hernia, Congenital diaphragmatic hernia |
| RS756636650 |
CASQ2
|
Health Risk |
Pathogenic/Likely pathogenic |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 2 |
| RS756637497 |
AHI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 3, Joubert syndrome |
| RS756637706 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS756638436 |
NHP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Dyskeratosis congenita |
| RS756638660 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS756639505 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS756639595 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756639609 |
QDPR
|
Health Risk |
Pathogenic/Likely pathogenic |
Dihydropteridine reductase deficiency, Dihydropteridine reductase deficiency |
| RS756640084 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS756640163 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
Otitis media, susceptibility to |
| RS756641209 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, VPS13B-related disorder |
| RS756641324 |
KIF22
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756642176 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |