SLITRK3 Chromosome 3

SLIT and NTRK like family member 3

1 variant 1 Health Risk

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What This Gene Does

This gene encodes a member of the Slitrk family of structurally related transmembrane proteins that are involved in controlling neurite outgrowth. The encoded protein contains two leucine-rich repeat (LRR) domains and a C-terminal domain that is partially similar to Trk neurotrophin receptor protein. Enhanced expression of this gene was found in tissue from several different types of tumors. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Jan 2016]

Gene Info

Gene Group

SLIT and NTRK like family

Locus Type

gene with protein product

Location

3q26.1

Ensembl

ENSG00000121871

Associated Conditions (1)

Intellectual disability

Key Variants

RS756582449

Pathogenic

Intellectual disability, Intellectual disability

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS756582449	Health Risk	Pathogenic	Intellectual disability, Intellectual disability