| RS756643740 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS756643992 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS756644243 |
RAB27A
|
Health Risk |
Pathogenic |
Griscelli syndrome type 2, Griscelli syndrome type 2 |
| RS756644736 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 12 |
| RS756646001 |
CYP11B1
|
Health Risk |
Pathogenic |
— |
| RS756646242 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756646275 |
FREM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculotrichoanal syndrome, Oculotrichoanal syndrome |
| RS756646859 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS756647770 |
BCKDHB
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease type 1A, Maple syrup urine disease |
| RS756648434 |
ABHD12
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756649389 |
NMNAT1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 9, Leber congenital amaurosis 9 |
| RS756650711 |
FANCI
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group I, Fanconi anemia |
| RS756650754 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS756650860 |
SLC22A5
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS756651509 |
NLGN4X
|
Health Risk |
Pathogenic |
Autism, susceptibility to |
| RS756651881 |
ARFGEF2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756652448 |
UNC13D
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS756653022 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS756653193 |
PMS2
|
Health Risk |
Pathogenic |
Lynch syndrome 4, Hereditary cancer-predisposing syndrome |
| RS756653973 |
NDUFV2
|
Health Risk |
Pathogenic |
— |
| RS756654236 |
HOXB13
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS756654353 |
FREM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculotrichoanal syndrome, Oculotrichoanal syndrome |
| RS756655815 |
ARMC9
|
Health Risk |
Likely pathogenic |
— |
| RS756656101 |
CTSC
|
Health Risk |
Pathogenic |
Haim-Munk syndrome, Periodontitis |
| RS756656568 |
PIBF1
|
Health Risk |
Pathogenic |
— |
| RS756658659 |
RHO
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary retinal dystrophy, Retinitis pigmentosa 4 |
| RS756659230 |
POGZ
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome, Intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome |
| RS756659644 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hereditary sensory and autonomic neuropathy type 7 |
| RS756660023 |
GNPTAB
|
Health Risk |
Likely pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS756663688 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS756663759 |
HSD3B2
|
Health Risk |
Likely pathogenic |
3 beta-Hydroxysteroid dehydrogenase deficiency, 3 beta-Hydroxysteroid dehydrogenase deficiency |
| RS756663920 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS75666426 |
NDUFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 5 |
| RS756664489 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Van Maldergem syndrome 2, Hennekam lymphangiectasia-lymphedema syndrome 2 |
| RS756664556 |
GARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS756664985 |
TREX1
|
Health Risk |
Pathogenic/Likely pathogenic |
TREX1-related disorder, Aicardi-Goutieres syndrome 1 |
| RS756665749 |
RPGRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 6, Cone-rod dystrophy 13 |
| RS756667241 |
LRSAM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2P, Charcot-Marie-Tooth disease axonal type 2P |
| RS756667462 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
WFS1-Related Spectrum Disorders, Autosomal dominant nonsyndromic hearing loss 6 |
| RS756667927 |
CSF3R
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe congenital neutropenia, Autosomal recessive severe congenital neutropenia due to CSF3R deficiency |
| RS756668931 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756670611 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS756670728 |
OCRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Lowe syndrome, Dent disease type 2 |
| RS756671027 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS756671283 |
GAA
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type II |
| RS756671977 |
ARSB
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS756672167 |
IL1RAPL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, X-linked 21 |
| RS756672670 |
COL4A4
|
Health Risk |
Pathogenic |
— |
| RS756673077 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS756674688 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1, Usher syndrome type 1 |
| RS756674774 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
WFS1-Related Spectrum Disorders, Autosomal dominant nonsyndromic hearing loss 6 |
| RS756675105 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756675225 |
LIFR
|
Health Risk |
Pathogenic |
Stuve-Wiedemann syndrome, Stüve-Wiedemann syndrome 1 |
| RS756675414 |
CHRNE
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome 4A, Congenital myasthenic syndrome 4C |
| RS756675590 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Hereditary cancer-predisposing syndrome |
| RS756676111 |
SDHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Pheochromocytoma/paraganglioma syndrome 3 |
| RS756676209 |
RAG2
|
Health Risk |
Likely pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS756676536 |
SLC19A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Biotin-responsive basal ganglia disease, Inborn genetic diseases |
| RS756677425 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS756677845 |
PINK1
|
Health Risk |
Pathogenic |
Autosomal recessive early-onset Parkinson disease 6, Autosomal recessive early-onset Parkinson disease 6 |
| RS756678484 |
CDHR1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 65, Retinal dystrophy |
| RS756678889 |
NR2E3
|
Health Risk |
Conflicting classifications of pathogenicity |
Enhanced S-cone syndrome, Retinal dystrophy |
| RS756679779 |
GNPTG
|
Health Risk |
Pathogenic |
— |
| RS756680042 |
RDH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS756680048 |
MAN2B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS756681683 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cowden syndrome 1, Hereditary cancer-predisposing syndrome |
| RS756682607 |
PROS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombophilia due to protein S deficiency, autosomal recessive |
| RS756683242 |
LAMC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756684256 |
BBS5
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS756684628 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Brain abnormalities, neurodegeneration |
| RS756684680 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS756685605 |
SLC34A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypophosphatemic nephrolithiasis/osteoporosis 1, Hypercalcemia |
| RS756685797 |
GYS2
|
Health Risk |
Likely pathogenic |
Glycogen storage disorder due to hepatic glycogen synthase deficiency, Glycogen storage disorder due to hepatic glycogen synthase deficiency |
| RS756686115 |
TMEM67
|
Health Risk |
Pathogenic |
Joubert syndrome 6, Meckel-Gruber syndrome |
| RS756686919 |
ZEB2
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS756687157 |
DNAH5
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS756687932 |
ALDH3A2
|
Health Risk |
Likely pathogenic |
Sjögren-Larsson syndrome, Sjögren-Larsson syndrome |
| RS756689063 |
DYSF
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS756689732 |
PRX
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease |
| RS756690468 |
ALDH18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
ALDH18A1-related de Barsy syndrome, de Barsy syndrome |
| RS756690487 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, GALC-related disorder |
| RS756690615 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756690940 |
TRPM1
|
Health Risk |
Likely pathogenic |
— |
| RS756691187 |
POGZ
|
Health Risk |
association |
Autism spectrum disorder, Autism spectrum disorder |
| RS756691827 |
FANCI
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group I |
| RS756692067 |
ASL
|
Health Risk |
Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS756692170 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial focal epilepsy with variable foci, Inborn genetic diseases |
| RS756692340 |
PCDH15
|
Health Risk |
Likely pathogenic |
Usher syndrome type 1F, Autosomal recessive nonsyndromic hearing loss 23 |
| RS756692505 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS756692621 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS756693072 |
MFN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS756693906 |
EMX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756694090 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS756694303 |
THAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Torsion dystonia 6, Inborn genetic diseases |
| RS756694568 |
COL9A2
|
Health Risk |
Conflicting classifications of pathogenicity |
COL9A2-related disorder, Epiphyseal dysplasia |
| RS756694755 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Complement component 3 deficiency, Atypical hemolytic-uremic syndrome with C3 anomaly |
| RS756694972 |
RAG2
|
Health Risk |
Pathogenic/Likely pathogenic |
Recombinase activating gene 2 deficiency, Inborn error of immunity |
| RS756695526 |
DRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756696262 |
RARS2
|
Health Risk |
Pathogenic |
Pontocerebellar hypoplasia type 6, Pontocerebellar hypoplasia type 6 |
| RS756696562 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |