| RS756839375 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS756839691 |
CPT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine palmitoyl transferase II deficiency, severe infantile form |
| RS756840095 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe early-childhood-onset retinal dystrophy, Retinal dystrophy |
| RS756840415 |
FAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Karyomegalic interstitial nephritis, Karyomegalic interstitial nephritis |
| RS756840607 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS756840659 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS756840753 |
GIPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 15 |
| RS756841034 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS756842462 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS756843954 |
MLH1
|
Health Risk |
Pathogenic |
Colorectal cancer, hereditary nonpolyposis |
| RS756844068 |
HOXD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Brachydactyly type D, Syndactyly type 5 |
| RS756845439 |
ACD
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Dyskeratosis congenita |
| RS756846388 |
PXDN
|
Health Risk |
Pathogenic |
Anterior segment dysgenesis 7, Anterior segment dysgenesis 7 |
| RS756846639 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS756847009 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS756847080 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Inborn genetic diseases |
| RS756847750 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Centronuclear myopathy, Malignant hyperthermia |
| RS756848112 |
PMM2
|
Health Risk |
Pathogenic/Likely pathogenic |
PMM2-congenital disorder of glycosylation, PMM2-congenital disorder of glycosylation |
| RS756848600 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS756848924 |
CLN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Neuronal ceroid lipofuscinosis 3 |
| RS756849358 |
LOX
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS756850637 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS756850884 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756851431 |
DNAH8
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756851981 |
IMPDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756852655 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS756853299 |
MKS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 13, Joubert syndrome 28 |
| RS756853672 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS756853742 |
SRD5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency, 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency |
| RS756853895 |
NPC1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type C1 |
| RS756854513 |
LAMA2
|
Health Risk |
Pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS756855066 |
TARS2
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation defect type 21, Combined oxidative phosphorylation defect type 21 |
| RS756855460 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756855492 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756855585 |
ABCA3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary pulmonary alveolar proteinosis, Interstitial lung disease due to ABCA3 deficiency |
| RS75685607 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS756856188 |
CPLANE1
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 17, Nephronophthisis |
| RS756856544 |
TULP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 15, Leber congenital amaurosis 15 |
| RS756856961 |
ABCC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1O, Cardiovascular phenotype |
| RS756857216 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4 |
| RS756858234 |
SPP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS756858649 |
NPR2
|
Health Risk |
Likely pathogenic |
Acromesomelic dysplasia 1, Maroteaux type |
| RS756859037 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS756859126 |
ASS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Citrullinemia type I, Citrullinemia |
| RS756859244 |
TUBGCP6
|
Health Risk |
Pathogenic |
— |
| RS756859863 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS756859993 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS756859994 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Inborn genetic diseases |
| RS756860453 |
SI
|
Health Risk |
Likely pathogenic |
— |
| RS756861229 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS756862725 |
DSG4
|
Health Risk |
Likely pathogenic |
— |
| RS756863324 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756863825 |
SLC22A5
|
Health Risk |
Pathogenic |
Renal carnitine transport defect, Decreased circulating carnitine concentration |
| RS756864231 |
ETFA
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS756864793 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1HH, Myofibrillar myopathy 6 |
| RS756865273 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Pallister-Hall syndrome, Greig cephalopolysyndactyly syndrome |
| RS756865623 |
VPS13A
|
Health Risk |
Pathogenic/Likely pathogenic |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS756865833 |
NAGLU
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-B |
| RS756866953 |
GABRB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, childhood absence |
| RS75686697 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal hypodysplasia/aplasia 1, Multiple endocrine neoplasia |
| RS756867102 |
LYST
|
Health Risk |
Pathogenic |
Chédiak-Higashi syndrome, Chédiak-Higashi syndrome |
| RS756868374 |
DNAI2
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS756868452 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS756868871 |
IL17RC
|
Health Risk |
Conflicting classifications of pathogenicity |
Candidiasis, familial |
| RS756868889 |
RSPH4A
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 11 |
| RS756869400 |
DDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of aromatic-L-amino-acid decarboxylase, Deficiency of aromatic-L-amino-acid decarboxylase |
| RS756869880 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Type 2 diabetes mellitus, Wolfram syndrome 1 |
| RS756870293 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, Abnormality of the musculature |
| RS756871251 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756871628 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS756871980 |
PCDH19
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 9 |
| RS756874468 |
UQCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756874525 |
SPINK5
|
Health Risk |
Pathogenic |
Ichthyosis linearis circumflexa, Netherton syndrome |
| RS756874724 |
RANBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial acute necrotizing encephalopathy, Familial acute necrotizing encephalopathy |
| RS756874949 |
SLC2A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi-Bickel syndrome, Type 2 diabetes mellitus |
| RS756874994 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS756876301 |
PEX1
|
Health Risk |
Likely pathogenic |
Heimler syndrome 1, Peroxisome biogenesis disorder 1A (Zellweger) |
| RS756877019 |
MUSK
|
Health Risk |
Likely pathogenic |
Congenital myasthenic syndrome 9, Congenital myasthenic syndrome 9 |
| RS756877451 |
DYM
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyggve-Melchior-Clausen syndrome, Dyggve-Melchior-Clausen syndrome |
| RS756877794 |
COL27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Steel syndrome, Steel syndrome |
| RS756878418 |
GLB1
|
Health Risk |
Pathogenic |
GM1 gangliosidosis type 2, Infantile GM1 gangliosidosis |
| RS756879546 |
POLG
|
Health Risk |
Likely pathogenic |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS756879840 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hemorrhage |
| RS756879923 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
ASPM-related disorder, ASPM-related disorder |
| RS756880457 |
WRN
|
Health Risk |
Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS756880678 |
LRSAM1
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease axonal type 2P |
| RS756880941 |
ERCC8
|
Health Risk |
Pathogenic/Likely pathogenic |
UV-sensitive syndrome 2, Cockayne syndrome type 1 |
| RS756881285 |
ADA2
|
Health Risk |
Pathogenic |
Splenomegaly, Deficiency of adenosine deaminase 2 |
| RS756881667 |
SFRP4
|
Health Risk |
Pathogenic |
— |
| RS756882582 |
FDXR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Auditory neuropathy-optic atrophy syndrome |
| RS756883400 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 4 |
| RS756883456 |
TRAPPC11
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS756884829 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS756885337 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS756885471 |
CNGB1
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS756886302 |
RAB3GAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Warburg micro syndrome 2, Martsolf syndrome |
| RS756886777 |
DNHD1
|
Health Risk |
Pathogenic |
Spermatogenic failure 65, Spermatogenic failure 65 |
| RS756888773 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS756888841 |
INPP5E
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Inborn genetic diseases |
| RS756890722 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |