| RS757007819 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS757007907 |
LPIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757008581 |
CYP7B1
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS757008969 |
POLA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757010758 |
ALOXE3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 3, Autosomal recessive congenital ichthyosis 3 |
| RS757010863 |
SLC30A8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757010959 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS757011098 |
NEK9
|
Health Risk |
Pathogenic |
NEK9-related lethal skeletal dysplasia, NEK9-related lethal skeletal dysplasia |
| RS757011771 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS757011861 |
NEFH
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS75701196 |
COG6
|
Health Risk |
Likely pathogenic |
COG6-congenital disorder of glycosylation, Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome |
| RS757012294 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Birt-Hogg-Dube syndrome 1 |
| RS757012840 |
NTRK1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS757012933 |
MCPH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 1, primary |
| RS757013679 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS757013900 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS757015172 |
GUSB
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 7, Mucopolysaccharidosis type 7 |
| RS757016287 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS757018821 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757018930 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS757019335 |
INVS
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS757019364 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS757020167 |
SLC22A12
|
Health Risk |
Conflicting classifications of pathogenicity |
Dalmatian hypouricemia, Dalmatian hypouricemia |
| RS757020181 |
PHOX2B
|
Health Risk |
Pathogenic |
Congenital central hypoventilation, Hereditary cancer-predisposing syndrome |
| RS757021413 |
NEFH
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757021648 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS757023317 |
CHRNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS757025272 |
EMC1
|
Health Risk |
Pathogenic |
Retinal dystrophy, Cerebellar atrophy |
| RS757026025 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS757026184 |
VARS1
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with microcephaly, seizures |
| RS757027394 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Wolfram syndrome 1, Autosomal dominant nonsyndromic hearing loss 6 |
| RS757027463 |
RHOBTB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757027638 |
PCDH15
|
Health Risk |
Likely pathogenic |
Usher syndrome type 1F, Autosomal recessive nonsyndromic hearing loss 23 |
| RS757027644 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS757027813 |
SYN1
|
Health Risk |
Pathogenic |
Epilepsy, X-linked 1 |
| RS757028149 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Saldino-Mainzer syndrome |
| RS757028268 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Macular degeneration |
| RS757030384 |
PDE6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757030913 |
MUSK
|
Health Risk |
Likely pathogenic |
Congenital myasthenic syndrome 9, Fetal akinesia deformation sequence 1 |
| RS757031050 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Inborn genetic diseases |
| RS757031567 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS757032044 |
RECQL4
|
Health Risk |
Pathogenic |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS757032537 |
ADAMTSL4
|
Health Risk |
Pathogenic/Likely pathogenic |
Ectopia lentis 2, isolated |
| RS757033341 |
NR3C2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant pseudohypoaldosteronism type 1, Pseudohyperaldosteronism type 2 |
| RS757033378 |
MMACHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cobalamin C disease, Cobalamin C disease |
| RS757033443 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757033561 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS757033996 |
HSD3B2
|
Health Risk |
Pathogenic |
3 beta-Hydroxysteroid dehydrogenase deficiency, 3 beta-Hydroxysteroid dehydrogenase deficiency |
| RS757034536 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 1, Perry syndrome |
| RS757034687 |
SIN3A
|
Health Risk |
Pathogenic |
— |
| RS757034771 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS757034991 |
GPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Simpson-Golabi-Behmel syndrome type 1 |
| RS757035494 |
SETD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Luscan-Lumish syndrome, Inborn genetic diseases |
| RS757037466 |
ERBB2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757040670 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCB11-related disorder, ABCB11-related disorder |
| RS757040733 |
PMM2
|
Health Risk |
Likely pathogenic |
PMM2-congenital disorder of glycosylation, PMM2-congenital disorder of glycosylation |
| RS757040754 |
ASXL1
|
Health Risk |
Pathogenic |
Bohring-Opitz syndrome, Bohring-Opitz syndrome |
| RS757041809 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiomyopathy |
| RS757042397 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS757042460 |
SGPL1
|
Health Risk |
Pathogenic |
— |
| RS757043077 |
NDUFAF5
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 16 |
| RS757043221 |
CNTNAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cortical dysplasia-focal epilepsy syndrome, Cortical dysplasia-focal epilepsy syndrome |
| RS757044850 |
HNF1B
|
Health Risk |
Uncertain risk allele |
Maturity-onset diabetes of the young, Maturity-onset diabetes of the young |
| RS757045433 |
CACNA1S
|
Health Risk |
Pathogenic |
Hypokalemic periodic paralysis, type 1 |
| RS757045842 |
CFH
|
Health Risk |
Conflicting classifications of pathogenicity |
CFH-Related Dense Deposit Disease / Membranoproliferative Glomerulonephritis Type II, Age related macular degeneration 4 |
| RS757046319 |
ODAD3
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia 30, Primary ciliary dyskinesia 30 |
| RS757046360 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish type amyloidosis, Finnish type amyloidosis |
| RS757047748 |
TTN
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS757049933 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 12 |
| RS757050033 |
ITGB4
|
Health Risk |
Pathogenic |
Junctional epidermolysis bullosa with pyloric atresia, Epidermolysis bullosa |
| RS757050478 |
WNK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS757050909 |
DNAH9
|
Health Risk |
Pathogenic |
— |
| RS757051221 |
TPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of iodide peroxidase, Deficiency of iodide peroxidase |
| RS757051244 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Rubinstein-Taybi syndrome |
| RS757051385 |
DDR2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757051494 |
FANCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS757051705 |
ADGRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757052602 |
MCCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, Methylcrotonyl-CoA carboxylase deficiency |
| RS757053149 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS757053706 |
CDH23
|
Health Risk |
Pathogenic |
Usher syndrome type 1D, Usher syndrome type 1D |
| RS757053954 |
CFI
|
Health Risk |
Pathogenic/Likely pathogenic |
Age related macular degeneration 13, Factor I deficiency |
| RS757053983 |
KRT25
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757055217 |
COL17A1
|
Health Risk |
Pathogenic |
— |
| RS757055499 |
AP4M1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 50, Hereditary spastic paraplegia 50 |
| RS757055720 |
PALB2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS757056658 |
RECQL
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS757057136 |
DNAH9
|
Health Risk |
Pathogenic |
— |
| RS757057677 |
GRM6
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness 1B, Congenital stationary night blindness 1B |
| RS757057811 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS757059523 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Greig cephalopolysyndactyly syndrome, Polydactyly |
| RS757060348 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS757060689 |
COLQ
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome 5, Congenital myasthenic syndrome 5 |
| RS757060708 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS757061042 |
ARSB
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS757061289 |
SLC5A2
|
Health Risk |
Likely pathogenic |
SLC5A2-related disorder, SLC5A2-related disorder |
| RS757062073 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, type 4 |
| RS757063739 |
ETFDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS757064470 |
CLDN16
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary hypomagnesemia, Primary hypomagnesemia |
| RS757064799 |
TMPRSS3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 8, Autosomal recessive nonsyndromic hearing loss 8 |
| RS757065157 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic right ventricular dysplasia 11 |