| RS756891007 |
PEX2
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder 5A (Zellweger), Peroxisome biogenesis disorder 5B |
| RS756891047 |
SCP2
|
Health Risk |
Pathogenic |
— |
| RS756891880 |
FAM161A
|
Health Risk |
Likely pathogenic |
— |
| RS756892237 |
NLRP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cryopyrin associated periodic syndrome, Cryopyrin associated periodic syndrome |
| RS756894409 |
ALG8
|
Health Risk |
Likely pathogenic |
ALG8 congenital disorder of glycosylation, Polycystic liver disease 3 with or without kidney cysts |
| RS756896276 |
CNTNAP1
|
Health Risk |
Pathogenic |
Neuropathy, congenital hypomyelinating |
| RS756896976 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS756897026 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa simplex 1A |
| RS756897044 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, Inborn genetic diseases |
| RS756897237 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS756897517 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Telangiectasia, hereditary hemorrhagic |
| RS756897581 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Cornelia de Lange syndrome 1 |
| RS756898709 |
ADAMTS13
|
Health Risk |
Conflicting classifications of pathogenicity |
Upshaw-Schulman syndrome, Upshaw-Schulman syndrome |
| RS756898971 |
SIPA1L3
|
Health Risk |
Pathogenic |
Cataract 45, Cataract 45 |
| RS756899044 |
ATM
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS756899141 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiac arrhythmia |
| RS756902589 |
EIF2AK4
|
Health Risk |
Pathogenic |
Familial pulmonary capillary hemangiomatosis, Familial pulmonary capillary hemangiomatosis |
| RS756903507 |
GATA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrioventricular septal defect 4, Cardiovascular phenotype |
| RS756903689 |
NMNAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 9, Leber congenital amaurosis 9 |
| RS756905236 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS756906403 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS756907367 |
CNTN1
|
Health Risk |
Pathogenic |
Compton-North congenital myopathy, Compton-North congenital myopathy |
| RS756907665 |
SDCCAG8
|
Health Risk |
Likely pathogenic |
Senior-Loken syndrome 7, Bardet-Biedl syndrome 16 |
| RS756908062 |
NRXN1
|
Health Risk |
Pathogenic |
Pitt-Hopkins-like syndrome 2, Pitt-Hopkins-like syndrome 2 |
| RS756908183 |
F11
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary factor XI deficiency disease, Abnormal bleeding |
| RS756909627 |
MTMR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, Inborn genetic diseases |
| RS756910200 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures, Spastic paraplegia |
| RS756910757 |
ABCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCC6-related disorder, ABCC6-related disorder |
| RS756911727 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS756911979 |
JAG1
|
Health Risk |
Likely pathogenic |
Hepatic Ductular Hypoplasia, Hepatic Ductular Hypoplasia |
| RS756912142 |
AFG3L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 28, Spinocerebellar ataxia type 28 |
| RS756912205 |
PIGU
|
Health Risk |
Pathogenic |
Glycosylphosphatidylinositol biosynthesis defect 21, Glycosylphosphatidylinositol biosynthesis defect 21 |
| RS756912340 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS756912360 |
HEXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Sandhoff disease, Sandhoff disease |
| RS756912703 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia 10 |
| RS756912930 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS756913474 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 4, Nephronophthisis 12 |
| RS756916028 |
APOC2
|
Health Risk |
Likely pathogenic |
APOLIPOPROTEIN C-II (ST. MICHAEL), Familial apolipoprotein C-II deficiency |
| RS756916740 |
C2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756917060 |
MYOM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS756917169 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS756918282 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS756918960 |
OCA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Tyrosinase-positive oculocutaneous albinism, Tyrosinase-positive oculocutaneous albinism |
| RS756919162 |
FERRY3
|
Health Risk |
Likely pathogenic |
C12orf4-related disorder, C12orf4-related disorder |
| RS756919169 |
DNAH8
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756920137 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS756920981 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS756921041 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS756921125 |
WWOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 1 |
| RS756921157 |
ALG14
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 15, Intellectual developmental disorder with epilepsy |
| RS756921209 |
EXT2
|
Health Risk |
Likely pathogenic |
Exostoses, multiple |
| RS756921311 |
IVNS1ABP
|
Health Risk |
Pathogenic |
Immunodeficiency 70, Immunodeficiency 70 |
| RS756921502 |
TBX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Scoliosis, Scoliosis |
| RS756921902 |
KCNQ2
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 7 |
| RS756922825 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756923555 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Cardiomyopathy |
| RS756924858 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS756925801 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS756926807 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS756927098 |
SELENON
|
Health Risk |
Pathogenic/Likely pathogenic |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS756928158 |
GJB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth Neuropathy X, Charcot-Marie-Tooth disease X-linked dominant 1 |
| RS756928373 |
GPR179
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness 1E, Congenital stationary night blindness 1E |
| RS756929892 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Wilson disease |
| RS756930611 |
NFKBIA
|
Health Risk |
Conflicting classifications of pathogenicity |
Ectodermal dysplasia and immunodeficiency 2, Ectodermal dysplasia and immunodeficiency 2 |
| RS756930722 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS756931255 |
LAMB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pierson syndrome, LAMB2-related infantile-onset nephrotic syndrome |
| RS756931329 |
CPT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine palmitoyl transferase II deficiency, severe infantile form |
| RS756931963 |
CRB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 8, Retinitis pigmentosa 12 |
| RS756932413 |
BCS1L
|
Health Risk |
Conflicting classifications of pathogenicity |
GRACILE syndrome, Leigh syndrome |
| RS756933390 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS756933506 |
ANK1
|
Health Risk |
Pathogenic |
— |
| RS756933588 |
LPIN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Majeed syndrome, Majeed syndrome |
| RS756935130 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS756935530 |
MTFMT
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756935554 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS756935623 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease type 2 |
| RS756938019 |
TUBA3D
|
Health Risk |
Pathogenic |
Keratoconus 9, Keratoconus 9 |
| RS756938071 |
CDH1
|
Health Risk |
Pathogenic |
Hereditary diffuse gastric adenocarcinoma, Hereditary diffuse gastric adenocarcinoma |
| RS756938942 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS756939943 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 65, Developmental and epileptic encephalopathy |
| RS756940046 |
ATP2A1
|
Health Risk |
Pathogenic |
Brody myopathy, Brody myopathy |
| RS756942664 |
B4GALT7
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome progeroid type, Ehlers-Danlos syndrome |
| RS756942804 |
SZT2
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 18 |
| RS756942890 |
ALG1
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG1-congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |
| RS756943416 |
NOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Blau syndrome, Inflammatory bowel disease 1 |
| RS756943739 |
IQCB1
|
Health Risk |
Pathogenic |
Senior-Loken syndrome 5, Senior-Loken syndrome 5 |
| RS756944795 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial spontaneous pneumothorax, Birt-Hogg-Dube syndrome |
| RS756945139 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS756945300 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756946393 |
WNT10A
|
Health Risk |
Pathogenic |
Tooth agenesis, selective |
| RS756946899 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS756947754 |
CNTNAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cortical dysplasia-focal epilepsy syndrome, Autism |
| RS756948486 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS756948772 |
DDX11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Warsaw breakage syndrome |
| RS756948868 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS756949024 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756949497 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS756949505 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS756950169 |
LIPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolman disease, Cardiovascular phenotype |
| RS756950646 |
ARHGAP24
|
Health Risk |
Conflicting classifications of pathogenicity |
— |