| RS756329385 |
WDR19
|
Health Risk |
Likely pathogenic |
Asphyxiating thoracic dystrophy 5, Senior-Loken syndrome 8 |
| RS756329704 |
RB1
|
Health Risk |
Pathogenic |
Retinoblastoma, Retinoblastoma |
| RS756331568 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, RYR1-related myopathy |
| RS756332498 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS756332675 |
SIK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 30 |
| RS756332789 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS756333430 |
IDH3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 90, Retinitis pigmentosa 90 |
| RS756335904 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756335940 |
TRPM1
|
Health Risk |
Pathogenic |
— |
| RS756336099 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756336949 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS756337302 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Ehlers-Danlos syndrome |
| RS756337473 |
CPS1
|
Health Risk |
Pathogenic |
Congenital hyperammonemia, type I |
| RS756337758 |
AARS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS756338119 |
SAMHD1
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 5, Aicardi-Goutieres syndrome 5 |
| RS756339433 |
ABCG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Sitosterolemia, Cardiovascular phenotype |
| RS756339648 |
TTN
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS756339822 |
NDUFAF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 1 |
| RS756339957 |
ASL
|
Health Risk |
Pathogenic/Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS756341043 |
CACNA2D4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal cone dystrophy 4, Retinal cone dystrophy 4 |
| RS756341143 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Woolly hair-skin fragility syndrome |
| RS756341249 |
ARL6
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 3, Retinitis pigmentosa 55 |
| RS756341605 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel syndrome, type 6 |
| RS756341923 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Dilated cardiomyopathy 1G |
| RS756342135 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS756342212 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Telangiectasia, hereditary hemorrhagic |
| RS756343304 |
TSEN54
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontoneocerebellar hypoplasia, Pontocerebellar hypoplasia type 4 |
| RS756344458 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS756344990 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS756345976 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS756345989 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS756346998 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Attenuated familial adenomatous polyposis |
| RS756347672 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS756347993 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS756348570 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 10, Spastic paraplegia |
| RS756348656 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Congenital contractural arachnodactyly |
| RS756350869 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS756351856 |
TAF15
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756352033 |
ASPRV1
|
Health Risk |
Pathogenic |
Autosomal dominant lamellar ichthyosis, Autosomal dominant lamellar ichthyosis |
| RS756352186 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS756352775 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756352952 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS756353660 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Batten-Turner congenital myopathy, Congenital myotonia |
| RS756353784 |
FLG
|
Health Risk |
Likely pathogenic |
Dermatitis, atopic |
| RS756353876 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS756355930 |
PC
|
Health Risk |
Pathogenic |
Pyruvate carboxylase deficiency, Pyruvate carboxylase deficiency |
| RS756357907 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS756358402 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS756358409 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Peroxisome biogenesis disorder |
| RS756358866 |
PMS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS756360188 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS756360226 |
KCNQ2
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS756360361 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS756360655 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stickler syndrome type 1, Type 2 collagenopathy |
| RS756361030 |
TRAPPC12
|
Health Risk |
Pathogenic |
Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome, Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome |
| RS756361248 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS756361392 |
SLC26A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis, type IB |
| RS756361785 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756362905 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS756363516 |
ASL
|
Health Risk |
Pathogenic/Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS756363734 |
NBN
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS756363870 |
PYCR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive cutis laxa type 2B |
| RS756363927 |
SH3KBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756363951 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS756364348 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756365280 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Amenorrhea, Inborn genetic diseases |
| RS756366019 |
SMPD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Sphingomyelin/cholesterol lipidosis, Niemann-Pick disease |
| RS756367182 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS756367276 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS756367933 |
TTN
|
Health Risk |
Likely pathogenic |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1G |
| RS756368261 |
KIF7
|
Health Risk |
Conflicting classifications of pathogenicity |
Acrocallosal syndrome, KIF7-related disorder |
| RS756368560 |
MKS1
|
Health Risk |
Pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS756368998 |
COX15
|
Health Risk |
Pathogenic |
— |
| RS756369937 |
GABRB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, childhood absence |
| RS756370084 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis 4 |
| RS756370324 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS756372984 |
GCDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Glutaric aciduria, type 1 |
| RS756374268 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS756376477 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic right ventricular dysplasia 9 |
| RS756377315 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756377692 |
NKX2-5
|
Health Risk |
Pathogenic |
Atrial septal defect 7, Atrial septal defect 7 |
| RS756378362 |
EPG5
|
Health Risk |
Likely pathogenic |
Vici syndrome, Vici syndrome |
| RS756378949 |
LRP5
|
Health Risk |
Pathogenic |
— |
| RS756379625 |
DOCK6
|
Health Risk |
Likely pathogenic |
— |
| RS756380512 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS756380526 |
BBS9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS756382250 |
GRIN2A
|
Health Risk |
Likely pathogenic |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS756382502 |
SDHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Pheochromocytoma/paraganglioma syndrome 3 |
| RS756384471 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS756384834 |
RAG1
|
Health Risk |
Likely pathogenic |
Combined immunodeficiency due to partial RAG1 deficiency, Severe combined immunodeficiency |
| RS756384880 |
AP4E1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS756385578 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, FG syndrome |
| RS756385625 |
CLCN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukoencephalopathy with mild cerebellar ataxia and white matter edema, Epilepsy |
| RS756386867 |
SRPX
|
Health Risk |
Likely pathogenic |
Short stature, Short stature |
| RS756387018 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, CREBBP-related disorder |
| RS756387775 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS756388778 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, Inborn genetic diseases |
| RS756389027 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS756389249 |
SPTBN1
|
Health Risk |
Pathogenic |
Developmental delay, impaired speech |
| RS756389970 |
PDE4D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |