| RS756135837 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS756136465 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS756136593 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS756136933 |
NAGA
|
Health Risk |
Pathogenic |
Alpha-N-acetylgalactosaminidase deficiency type 1, Alpha-N-acetylgalactosaminidase deficiency type 1 |
| RS756137377 |
IFNAR1
|
Health Risk |
Likely pathogenic |
— |
| RS756138074 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RYR1-related disorder |
| RS756140322 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS756140557 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia 48 |
| RS756140957 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS756141692 |
COASY
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Neurodegeneration with brain iron accumulation 6 |
| RS756141940 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS756142773 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial focal epilepsy with variable foci, Inborn genetic diseases |
| RS756143337 |
MYT1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756143769 |
POC1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 20, Cone-rod dystrophy 20 |
| RS756145065 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS756145453 |
TRIOBP
|
Health Risk |
Pathogenic/Likely pathogenic |
Hearing impairment, Hearing impairment |
| RS756146889 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS756147087 |
CDH23
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Sensorineural hearing loss disorder |
| RS756149444 |
VPS13C
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS756150298 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS756151512 |
HMOX1
|
Health Risk |
Pathogenic |
Heme oxygenase 1 deficiency, Heme oxygenase 1 deficiency |
| RS756151664 |
G6PC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS756151764 |
F7
|
Health Risk |
Pathogenic |
Congenital factor VII deficiency, F7-related disorder |
| RS756152752 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS756152942 |
PCARE
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa |
| RS756153007 |
DNAAF11
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia 19, Primary ciliary dyskinesia 19 |
| RS756153152 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS756153541 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS756154211 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS756154596 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS756155224 |
TG
|
Health Risk |
Conflicting classifications of pathogenicity |
Iodotyrosyl coupling defect, Iodotyrosyl coupling defect |
| RS756155242 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS756155678 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756155710 |
VEGFA
|
Health Risk |
Likely pathogenic |
— |
| RS756156581 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS756156901 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Pallister-Hall syndrome, Greig cephalopolysyndactyly syndrome |
| RS756156987 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS756158170 |
KRIT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cerebral cavernous malformation |
| RS756158801 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital nephrotic syndrome, NPHS1-related disorder |
| RS756158809 |
SLC6A19
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutral 1 amino acid transport defect, Neutral 1 amino acid transport defect |
| RS756159043 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS756159737 |
SCN5A
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiac arrhythmia, Cardiovascular phenotype |
| RS756160039 |
CCDC40
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 15 |
| RS756160145 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS756160533 |
ATM
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS756161883 |
LIFR
|
Health Risk |
Conflicting classifications of pathogenicity |
Stuve-Wiedemann syndrome, Stuve-Wiedemann syndrome |
| RS756162358 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS756163471 |
SLC2A2
|
Health Risk |
Likely pathogenic |
— |
| RS756164478 |
VMA22
|
Health Risk |
Pathogenic |
— |
| RS756165637 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS756166032 |
HK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hemolytic anemia due to hexokinase deficiency, Hemolytic anemia due to hexokinase deficiency |
| RS756167741 |
GAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756169949 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 12 |
| RS756170729 |
PCNT
|
Health Risk |
Pathogenic |
— |
| RS756170824 |
MAK
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS756171105 |
CEP104
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 25, Melanoma |
| RS756171491 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS756171835 |
GRM6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756172609 |
CNGA3
|
Health Risk |
Pathogenic/Likely pathogenic |
Achromatopsia 2, Achromatopsia 2 |
| RS756172692 |
ADCY5
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with hyperkinetic movements and dyskinesia, Neurodevelopmental disorder with hyperkinetic movements and dyskinesia |
| RS756173225 |
SFXN4
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Growth and developmental delay-hypotonia-vision impairment-lactic acidosis syndrome |
| RS756173722 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa, Epidermolysis bullosa |
| RS756174213 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS756175126 |
SIAE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756175624 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS756176112 |
TTN
|
Health Risk |
Likely pathogenic |
Myopathy, myofibrillar |
| RS75617691 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
A2ML1-related disorder, A2ML1-related disorder |
| RS756179543 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Piebaldism |
| RS756180389 |
KIF11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756180801 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS756181133 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 5 |
| RS756181827 |
SMAD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Aneurysm-osteoarthritis syndrome |
| RS756181906 |
TBC1D24
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS756181994 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS756182263 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS756182448 |
CTNS
|
Health Risk |
Pathogenic |
Cystinosis, Cystinosis |
| RS756182598 |
ZMIZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756182703 |
SLC25A13
|
Health Risk |
Pathogenic |
Citrin deficiency, Citrin deficiency |
| RS756182817 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 7, Familial episodic pain syndrome with predominantly lower limb involvement |
| RS756183569 |
TRAF5
|
Health Risk |
Likely pathogenic |
Multiple myeloma, Multiple myeloma |
| RS756185275 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS756185743 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Inborn genetic diseases |
| RS756190836 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS756190979 |
MSH3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 4 |
| RS756192072 |
SMPD1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type B |
| RS756192515 |
DNAJC19
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria type 5, 3-methylglutaconic aciduria type 5 |
| RS756192655 |
RAG2
|
Health Risk |
Likely pathogenic |
Combined immunodeficiency with skin granulomas, Severe combined immunodeficiency |
| RS756193571 |
HARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 3B, Usher syndrome type 3B |
| RS756193716 |
PEX12
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 3A (Zellweger), Peroxisome biogenesis disorder 3A (Zellweger) |
| RS756193988 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS756194499 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS756195113 |
PIGB
|
Health Risk |
Pathogenic |
— |
| RS756195409 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Pulmonary hypertension |
| RS756195450 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
SNRNP200-related disorder, SNRNP200-related disorder |
| RS756195567 |
POU4F3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 15, POU4F3-related disorder |
| RS756195708 |
MMAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblB type |
| RS756197350 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS756197388 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS756197493 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Joubert syndrome |
| RS756198077 |
POT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |