| RS755959856 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Inborn genetic diseases |
| RS755961162 |
COL7A1
|
Health Risk |
Likely pathogenic |
7 conditions, 7 conditions |
| RS755961343 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS755961411 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Benign familial hematuria |
| RS755961602 |
ADAMTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS755962173 |
DVL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755962512 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures, Inborn genetic diseases |
| RS755962697 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS755962971 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS755963597 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755963903 |
LAMB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, LAMB2-related infantile-onset nephrotic syndrome |
| RS755964792 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Malignant hyperthermia |
| RS755964863 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, Inborn genetic diseases |
| RS755965129 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS755965232 |
RTEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pulmonary fibrosis and/or bone marrow failure, Telomere-related |
| RS755966311 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS755966941 |
ERBB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glioma susceptibility 1, Lung cancer |
| RS755967000 |
TRAPPC12
|
Health Risk |
Likely pathogenic |
Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome, Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome |
| RS755967190 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS755967391 |
GRM6
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital stationary night blindness 1B, Congenital stationary night blindness 1B |
| RS755967723 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 2 |
| RS755968404 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS755968563 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755968761 |
FKRP
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Cardiovascular phenotype |
| RS755969165 |
MYH10
|
Health Risk |
Pathogenic |
7 conditions, 6 conditions |
| RS755969803 |
ENPP1
|
Health Risk |
Pathogenic |
Hypophosphatemic rickets, autosomal recessive |
| RS755969920 |
FBXW4
|
Health Risk |
Conflicting classifications of pathogenicity |
Split hand-foot malformation 3, Split hand-foot malformation 3 |
| RS755970186 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755970391 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS755970774 |
HPS4
|
Health Risk |
Likely pathogenic |
Hermansky-Pudlak syndrome 4, Hermansky-Pudlak syndrome 4 |
| RS755972186 |
XDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary xanthinuria type 1, Hereditary xanthinuria type 1 |
| RS755972674 |
NPHS2
|
Health Risk |
Pathogenic |
Nephrotic syndrome, type 2 |
| RS755972697 |
CDT1
|
Health Risk |
Pathogenic |
— |
| RS755972713 |
PKD1
|
Health Risk |
Pathogenic |
Autosomal dominant polycystic kidney disease, Autosomal dominant polycystic kidney disease |
| RS755972876 |
CFHR5
|
Health Risk |
Conflicting classifications of pathogenicity |
C3 glomerulonephritis, Inborn genetic diseases |
| RS755973004 |
ARG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Arginase deficiency, Arginase deficiency |
| RS755973480 |
LRPPRC
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type |
| RS755973863 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS755974092 |
ERCC6
|
Health Risk |
Pathogenic |
— |
| RS755974448 |
ARSA
|
Health Risk |
Pathogenic/Likely pathogenic |
Metachromatic leukodystrophy, ARSA-related disorder |
| RS755974871 |
TRDN
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 5 |
| RS755975244 |
ARG1
|
Health Risk |
Pathogenic |
Arginase deficiency, Arginase deficiency |
| RS755975670 |
NARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation defect type 24, NARS2-related disorder |
| RS755975980 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS755976129 |
COL9A1
|
Health Risk |
Likely pathogenic |
Stickler syndrome, type 4 |
| RS755976424 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS755976465 |
DHTKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
2-aminoadipic 2-oxoadipic aciduria, 2-aminoadipic 2-oxoadipic aciduria |
| RS755976776 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755977911 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS755978559 |
POLR3A
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukodystrophy, Leukodystrophy |
| RS755980571 |
VCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1W, Hypertrophic cardiomyopathy 15 |
| RS755981187 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS755981642 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS755983199 |
MYBPC3
|
Health Risk |
Pathogenic |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS755983212 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS755984510 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS755984905 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondylometaphyseal dysplasia - Sutcliffe type, Glomerulopathy with fibronectin deposits 2 |
| RS755985917 |
MID1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, X-linked Opitz G/BBB syndrome |
| RS755985958 |
TTC7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple gastrointestinal atresias, Multiple gastrointestinal atresias |
| RS755986012 |
IFITM5
|
Health Risk |
Conflicting classifications of pathogenicity |
IFITM5-related disorder, Inborn genetic diseases |
| RS755986694 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, Cystic fibrosis |
| RS755986911 |
SNTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 12, Cardiovascular phenotype |
| RS755987047 |
PCNT
|
Health Risk |
Pathogenic |
PCNT-related disorder, PCNT-related disorder |
| RS755987663 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS755987732 |
COL11A1
|
Health Risk |
Pathogenic |
Intervertebral disc disorder, Hearing loss |
| RS755989911 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS755989926 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS755989946 |
KATNIP
|
Health Risk |
Pathogenic/Likely pathogenic |
KATNIP-related disorder, KATNIP-related disorder |
| RS755990979 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS755992300 |
ALDH7A1
|
Health Risk |
Likely pathogenic |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS755992691 |
ATP6V0A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal tubular acidosis, distal |
| RS755992942 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Inborn genetic diseases |
| RS755993710 |
IL17RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 51, Immunodeficiency 51 |
| RS755994483 |
SIGMAR1
|
Health Risk |
Pathogenic |
Autosomal recessive distal spinal muscular atrophy 2, Amyotrophic lateral sclerosis type 16 |
| RS755994820 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS755995375 |
DNMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory neuropathy-deafness-dementia syndrome, Hereditary sensory neuropathy-deafness-dementia syndrome |
| RS755995964 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy due to partial LAMA2 deficiency, LAMA2-related muscular dystrophy |
| RS755996065 |
VPS13B
|
Health Risk |
Pathogenic/Likely pathogenic |
Cohen syndrome, VPS13B-related disorder |
| RS755996321 |
CACNA2D4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal cone dystrophy 4, Retinal cone dystrophy 4 |
| RS755996559 |
FLG
|
Health Risk |
Pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS755996862 |
ETV2
|
Health Risk |
Likely pathogenic |
Abnormal vertebral morphology, Hypoplastic left heart syndrome |
| RS755996999 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755997898 |
VSX2
|
Health Risk |
Pathogenic |
Isolated microphthalmia 2, Isolated microphthalmia 2 |
| RS755999681 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS755999834 |
GUCY2D
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 1, Leber congenital amaurosis 1 |
| RS756000896 |
GJB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth Neuropathy X |
| RS756001839 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756001994 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS756002498 |
RASA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Capillary malformation-arteriovenous malformation syndrome, Cardiovascular phenotype |
| RS756002632 |
DYNC2H1
|
Health Risk |
Pathogenic/Likely pathogenic |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 3 |
| RS756003242 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS756003817 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS756003832 |
BBS2
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 2, Retinitis pigmentosa 74 |
| RS756004566 |
WDR35
|
Health Risk |
Pathogenic/Likely pathogenic |
Cranioectodermal dysplasia 2, Short-rib thoracic dysplasia 7 with or without polydactyly |
| RS756004991 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS756005814 |
FRAS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS756006048 |
ERCC6L2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS756008087 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, DDX41-related hematologic malignancy predisposition syndrome |
| RS756008276 |
DYNC2H1
|
Health Risk |
Pathogenic/Likely pathogenic |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 3 |
| RS756008307 |
NAA60
|
Health Risk |
Pathogenic |
Basal ganglia calcification, idiopathic |