| RS755776820 |
PCCB
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |
| RS755777005 |
TGM6
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 35, Spinocerebellar ataxia type 35 |
| RS755777744 |
TG
|
Health Risk |
Pathogenic |
— |
| RS755777807 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS755779040 |
CEP250
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755780019 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS755780700 |
CSF2RB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755782051 |
RSPH4A
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS755782087 |
COLQ
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 5, Congenital myasthenic syndrome 5 |
| RS755782127 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 1 |
| RS755782924 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS755783122 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS755783378 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS755783618 |
CHAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial infantile myasthenia, Inborn genetic diseases |
| RS755783805 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, SOS2-related disorder |
| RS755786402 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS755786597 |
HIBCH
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS755786784 |
SLC39A8
|
Health Risk |
Conflicting classifications of pathogenicity |
SLC39A8-CDG, Inborn genetic diseases |
| RS755787013 |
LAMB2
|
Health Risk |
Likely pathogenic |
Nephrotic syndrome, Nephrotic syndrome |
| RS755789146 |
EVC2
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS755789450 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS755789696 |
RANBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial acute necrotizing encephalopathy, Familial acute necrotizing encephalopathy |
| RS755790570 |
CFH
|
Health Risk |
Pathogenic/Likely pathogenic |
Factor H deficiency, Atypical hemolytic-uremic syndrome |
| RS755791142 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS755791156 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS755791578 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS755791719 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS755791846 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS755792441 |
COL4A3
|
Health Risk |
Pathogenic |
— |
| RS755793186 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS755793521 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS755793630 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS755793871 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS755794886 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS755795110 |
SEC63
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal dominant polycystic liver disease, Polycystic liver disease 2 |
| RS755796609 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS755796820 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS755796920 |
NCF2
|
Health Risk |
Pathogenic |
— |
| RS755797350 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS755797374 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome 11 |
| RS755797497 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS755798109 |
PRKAR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carney complex, type 1 |
| RS755798626 |
TBCE
|
Health Risk |
Pathogenic |
— |
| RS755799226 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS755799430 |
VSX2
|
Health Risk |
Pathogenic |
Anophthalmia-microphthalmia syndrome, VSX2-related Microphthalmia |
| RS755799528 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS755799702 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS755800734 |
CCM2
|
Health Risk |
Pathogenic |
Cerebral cavernous malformation 2, CCM2-related disorder |
| RS755801203 |
CHD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755802114 |
BRAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal-onset encephalopathy with rigidity and seizures, Inborn genetic diseases |
| RS755802156 |
PRDM5
|
Health Risk |
Likely pathogenic |
Brittle cornea syndrome 2, Brittle cornea syndrome 2 |
| RS755802373 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Inborn genetic diseases |
| RS755803064 |
XPA
|
Health Risk |
Likely pathogenic |
Xeroderma pigmentosum group A, Xeroderma pigmentosum group A |
| RS755804518 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 39, Usher syndrome type 2A |
| RS755804651 |
GPSM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Deafness, Hearing loss |
| RS755805420 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS755805461 |
NBN
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS755806238 |
ACAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS755806405 |
DYRK1A
|
Health Risk |
Pathogenic |
DYRK1A-related intellectual disability syndrome, DYRK1A-related intellectual disability syndrome |
| RS755806449 |
VCAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Vitreoretinopathy, Inborn genetic diseases |
| RS755806668 |
APC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS755808099 |
MOCS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A |
| RS755809709 |
ABCG5
|
Health Risk |
Pathogenic |
Sitosterolemia, Sitosterolemia |
| RS75581470 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS755815057 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiomyopathy |
| RS755815612 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS755815669 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS755817220 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Inborn genetic diseases |
| RS755817854 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS755818010 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS755818414 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 14, Hypertrophic cardiomyopathy 14 |
| RS755818826 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Hearing impairment |
| RS755820155 |
NEK8
|
Health Risk |
Likely pathogenic |
Renal-hepatic-pancreatic dysplasia 2, Renal-hepatic-pancreatic dysplasia 2 |
| RS755820725 |
AP4S1
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Spastic paraplegia |
| RS755821378 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
MYO15A-related disorder, Inborn genetic diseases |
| RS755822013 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS755822321 |
TUBGCP4
|
Health Risk |
Pathogenic |
Microcephaly and chorioretinopathy 3, Microcephaly and chorioretinopathy 3 |
| RS755822641 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS755823086 |
STAR
|
Health Risk |
Likely pathogenic |
Congenital lipoid adrenal hyperplasia due to STAR deficency, STAR-related disorder |
| RS755823797 |
FLG
|
Health Risk |
Pathogenic |
— |
| RS755824618 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS755825264 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS755825482 |
TRPC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 2, Focal segmental glomerulosclerosis 2 |
| RS755825865 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 9, Primary ciliary dyskinesia |
| RS755825913 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS755826006 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS755826566 |
TG
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755827237 |
VPS13B
|
Health Risk |
Pathogenic |
Cohen syndrome, Cohen syndrome |
| RS755827664 |
HPS5
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome 5 |
| RS755827803 |
TGFBR1
|
Health Risk |
Likely pathogenic |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 1 |
| RS755828990 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniosynostosis syndrome, Osteoglophonic dysplasia |
| RS755829473 |
DNAJC12
|
Health Risk |
Pathogenic |
Hyperphenylalaninemia due to DNAJC12 deficiency, Hyperphenylalaninemia due to DNAJC12 deficiency |
| RS755830520 |
CPT2
|
Health Risk |
Likely pathogenic |
Carnitine palmitoyl transferase II deficiency, neonatal form |
| RS755831030 |
NUP133
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755832014 |
FLNC
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS755832695 |
GNB5
|
Health Risk |
Pathogenic/Likely pathogenic |
Gnb5-related intellectual disability-cardiac arrhythmia syndrome, Gnb5-related intellectual disability-cardiac arrhythmia syndrome |
| RS755832705 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS755833290 |
KDM5B
|
Health Risk |
Likely pathogenic |
— |
| RS755834578 |
ITGB2
|
Health Risk |
Likely pathogenic |
Leukocyte adhesion deficiency 1, Colon adenocarcinoma |
| RS755835144 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dystrophin deficiency |