| RS755711684 |
DICER1
|
Health Risk |
Pathogenic |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS755713308 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS755714246 |
ZP2
|
Health Risk |
Pathogenic |
Oocyte maturation defect 6, Oocyte maturation defect 6 |
| RS755714285 |
TMEM240
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755714542 |
CLCNKB
|
Health Risk |
Pathogenic/Likely pathogenic |
Bartter disease type 3, Bartter disease type 4B |
| RS755714858 |
DNAI2
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS755715459 |
SLC7A9
|
Health Risk |
Pathogenic |
Cystine urolithiasis, Cystinuria |
| RS755716405 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS755716475 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS755716827 |
MKKS
|
Health Risk |
Pathogenic |
McKusick-Kaufman syndrome, Bardet-Biedl syndrome |
| RS755716911 |
PEX6
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder, Heimler syndrome 2 |
| RS755717157 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Familial hemophagocytic lymphohistiocytosis 5 |
| RS755717160 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS755717662 |
ATL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS755718337 |
FLAD1
|
Health Risk |
Pathogenic |
— |
| RS755719248 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS755721902 |
NUP160
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteopetrosis, Osteopetrosis |
| RS755722952 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Lymphatic malformation 6 |
| RS755723511 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS755724489 |
HPS3
|
Health Risk |
Likely pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS755724766 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Bloom syndrome |
| RS755724779 |
CTNNA1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS755725531 |
RPGR
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Retinal dystrophy |
| RS755725702 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Inborn genetic diseases |
| RS755726554 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS755726905 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Idiopathic generalized epilepsy |
| RS755727938 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755728007 |
TSC2
|
Health Risk |
Pathogenic |
Tuberous sclerosis 2, Isolated focal cortical dysplasia type II |
| RS755728248 |
TYMP
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS755728923 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS755729832 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Werner syndrome |
| RS755729966 |
CYP7B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Congenital bile acid synthesis defect 3 |
| RS755731113 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 53, Otospondylomegaepiphyseal dysplasia |
| RS755731385 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, type 4 |
| RS755731853 |
KIZ
|
Health Risk |
Pathogenic |
— |
| RS755733328 |
ABCA4
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 3, Retinal dystrophy |
| RS755733512 |
CNGB3
|
Health Risk |
Likely pathogenic |
— |
| RS755734596 |
HGD
|
Health Risk |
Pathogenic/Likely pathogenic |
Alkaptonuria, Clear cell carcinoma of kidney |
| RS755736687 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS755737064 |
PRF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Aplastic anemia |
| RS755737169 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS755738894 |
DST
|
Health Risk |
Pathogenic |
Hereditary sensory and autonomic neuropathy type 6, Epidermolysis bullosa simplex 3 |
| RS755739341 |
CSPP1
|
Health Risk |
Pathogenic |
Joubert syndrome 21, Joubert syndrome 21 |
| RS755740633 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS755741122 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS755741181 |
COL13A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755742518 |
SLC3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystinuria, Cystinuria |
| RS755742775 |
SHOC1
|
Health Risk |
Pathogenic |
Spermatogenic failure 75, Spermatogenic failure 75 |
| RS755743750 |
GNE
|
Health Risk |
Likely pathogenic |
GNE myopathy, GNE myopathy |
| RS755744291 |
DNMT3A
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Tatton-Brown-Rahman overgrowth syndrome |
| RS755744719 |
AFG2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome, Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome |
| RS755745002 |
ARX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS755745806 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS755746417 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS755747010 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS755747435 |
ROBO4
|
Health Risk |
Likely pathogenic |
Ascending tubular aorta aneurysm, Bicuspid aortic valve |
| RS755747732 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS755748579 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS755749479 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755749772 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS755749925 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS755750516 |
PIGO
|
Health Risk |
Likely pathogenic |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS755750961 |
FRAS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS755751835 |
TXNRD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Primary dilated cardiomyopathy |
| RS755751855 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS755752316 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Finnish congenital nephrotic syndrome |
| RS755753053 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS755754433 |
COL6A3
|
Health Risk |
Likely pathogenic |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS755755175 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS755755790 |
CDK5RAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
CDK5RAP2-related disorder, CDK5RAP2-related disorder |
| RS755756363 |
AP4B1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 47, Hereditary spastic paraplegia 47 |
| RS755756538 |
UNC80
|
Health Risk |
Likely pathogenic |
— |
| RS755756797 |
ZFYVE26
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 15, Hereditary spastic paraplegia 15 |
| RS755757866 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS755758018 |
NSD1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS755758613 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Autoinflammatory syndrome |
| RS755758948 |
SPEN
|
Health Risk |
Pathogenic |
— |
| RS755760603 |
ERCC3
|
Health Risk |
Likely pathogenic |
Xeroderma pigmentosum group B, Trichothiodystrophy 2 |
| RS755760721 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS755762601 |
ELP4
|
Health Risk |
Likely pathogenic |
Global developmental delay, Seizure |
| RS755762622 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS755762723 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Alstrom syndrome |
| RS755763002 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS755763110 |
OTOGL
|
Health Risk |
Pathogenic |
— |
| RS755763965 |
JAGN1
|
Health Risk |
Likely pathogenic |
— |
| RS755764533 |
ERCC3
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum group B, Xeroderma pigmentosum group B |
| RS755764751 |
FAM20C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Thymoma |
| RS755765955 |
UBE3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Angelman syndrome, Angelman syndrome |
| RS755765979 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinitis pigmentosa |
| RS755766300 |
RDH5
|
Health Risk |
Pathogenic |
— |
| RS755766520 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
COL4A5-related disorder, X-linked Alport syndrome |
| RS755767180 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group D2, Fanconi anemia |
| RS755768331 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, Autoinflammatory syndrome |
| RS755769210 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Early-onset myopathy with fatal cardiomyopathy |
| RS755770649 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Fibromatosis |
| RS755771457 |
CHRNA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Urinary bladder, atony of |
| RS755775132 |
IGFALS
|
Health Risk |
Likely pathogenic |
— |
| RS755775223 |
GLE1
|
Health Risk |
Pathogenic |
— |
| RS755775428 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Inborn genetic diseases |
| RS755775484 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |