| RS755654853 |
EDAR
|
Health Risk |
Likely pathogenic |
Autosomal recessive hypohidrotic ectodermal dysplasia syndrome, Ectodermal dysplasia 10A |
| RS755654915 |
LHCGR
|
Health Risk |
Likely pathogenic |
LHCGR-related disorder, LHCGR-related disorder |
| RS755655527 |
WDR73
|
Health Risk |
Likely pathogenic |
— |
| RS755655903 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Seizure |
| RS755656180 |
VPS13C
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive early-onset Parkinson disease 23, Autosomal recessive early-onset Parkinson disease 23 |
| RS755656678 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755657932 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS755657969 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group C, Fanconi anemia |
| RS755658678 |
POLR3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism |
| RS755659037 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS755659741 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, RYR1-related disorder |
| RS755660222 |
POMT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS755660496 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS755660659 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiomyopathy |
| RS755660899 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS755660948 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS755661115 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS755661819 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS755664216 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS755665894 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS755665899 |
P3H1
|
Health Risk |
Pathogenic/Likely pathogenic |
Osteogenesis imperfecta type 8, Osteogenesis imperfecta type 8 |
| RS755666127 |
ATP8B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755666654 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS755667439 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS755667590 |
LIFR
|
Health Risk |
Pathogenic |
— |
| RS755667636 |
WNK1
|
Health Risk |
Pathogenic |
Neuropathy, hereditary sensory and autonomic |
| RS755667663 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS755669336 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS755669455 |
KAT6A
|
Health Risk |
Pathogenic |
Autosomal dominant intellectual disability-craniofacial anomalies-cardiac defects syndrome, Autosomal dominant intellectual disability-craniofacial anomalies-cardiac defects syndrome |
| RS755669902 |
COL7A1
|
Health Risk |
Pathogenic |
7 conditions, 7 conditions |
| RS755669926 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS755670651 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS755671269 |
RTTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755671694 |
PDSS2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755672192 |
KANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755672814 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS755672868 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Ehlers-Danlos syndrome |
| RS755673462 |
ACOX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Acyl-CoA oxidase deficiency, Acyl-CoA oxidase deficiency |
| RS755674457 |
QARS1
|
Health Risk |
Pathogenic |
Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome, Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome |
| RS755676676 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755676779 |
PRDM5
|
Health Risk |
Pathogenic |
Brittle cornea syndrome 2, Brittle cornea syndrome 2 |
| RS755678310 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Colorectal cancer |
| RS755678482 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
RAI1-related disorder, Inborn genetic diseases |
| RS755679221 |
SPTB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755680047 |
BCOR
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculofaciocardiodental syndrome, Oculofaciocardiodental syndrome |
| RS755681036 |
MTTP
|
Health Risk |
Pathogenic |
Abetalipoproteinaemia, Abetalipoproteinaemia |
| RS755681347 |
SKIC3
|
Health Risk |
Pathogenic/Likely pathogenic |
Trichohepatoenteric syndrome 1, Trichohepatoenteric syndrome 1 |
| RS755681714 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755682241 |
DRC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 33, Primary ciliary dyskinesia 33 |
| RS755685473 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral arteriopathy, autosomal dominant |
| RS755686224 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS755686359 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiomyopathy |
| RS755686699 |
PHEX
|
Health Risk |
Pathogenic |
— |
| RS755686768 |
C2CD3
|
Health Risk |
Likely pathogenic |
Orofaciodigital syndrome type 14, Orofaciodigital syndrome type 14 |
| RS755688765 |
AHI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 3 |
| RS755688912 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS755689589 |
FREM2
|
Health Risk |
Pathogenic |
— |
| RS755690994 |
CACNA2D4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755691060 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755691417 |
BCKDHA
|
Health Risk |
Pathogenic/Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 1A |
| RS755691445 |
DOCK2
|
Health Risk |
Pathogenic |
DOCK2 deficiency, DOCK2 deficiency |
| RS755693106 |
BARD1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS755693286 |
IVD
|
Health Risk |
Conflicting classifications of pathogenicity |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS755693369 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS755693576 |
SEMA4A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755693770 |
PRF1
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Aplastic anemia |
| RS755693951 |
UPB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of beta-ureidopropionase, Deficiency of beta-ureidopropionase |
| RS755694066 |
TMC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Autosomal recessive nonsyndromic hearing loss 7 |
| RS755694590 |
AQP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Diabetes insipidus, nephrogenic |
| RS755694640 |
EXT1
|
Health Risk |
Pathogenic |
Exostoses, multiple |
| RS755697363 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS755698372 |
KCNH2
|
Health Risk |
Pathogenic |
— |
| RS755698791 |
SMO
|
Health Risk |
Pathogenic |
Congenital hypothalamic hamartoma syndrome, Congenital hypothalamic hamartoma syndrome |
| RS755698899 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS755699416 |
IFITM5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755699992 |
PLEKHG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS755700079 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS755700206 |
ZDHHC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability Raymond type, Syndromic X-linked intellectual disability Raymond type |
| RS755700350 |
F11
|
Health Risk |
Likely pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS755700581 |
TYR
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1A |
| RS755700844 |
RFWD3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755700896 |
B3GALT6
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, spondylodysplastic type |
| RS755701957 |
PMP22
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease |
| RS755702632 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755704105 |
ACTL7A
|
Health Risk |
Pathogenic |
Spermatogenic failure 86, Spermatogenic failure 86 |
| RS755704180 |
RB1
|
Health Risk |
Pathogenic |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS755704498 |
EIF2AK3
|
Health Risk |
Pathogenic |
— |
| RS755705038 |
ASNS
|
Health Risk |
Likely pathogenic |
— |
| RS755706305 |
JAK3
|
Health Risk |
Pathogenic/Likely pathogenic |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, T-B+ severe combined immunodeficiency due to JAK3 deficiency |
| RS755706526 |
MYH7
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS755707625 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS755708141 |
VPS13A
|
Health Risk |
Pathogenic |
— |
| RS755709270 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Wilson disease |
| RS755709525 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS755709669 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755709828 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome, Brain small vessel disease 1 with or without ocular anomalies |
| RS755710040 |
HGSNAT
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS755710579 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, PKHD1-related disorder |
| RS755711135 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS755711481 |
PYCR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa, Cutis laxa |