| RS755579388 |
SLC1A1
|
Health Risk |
Likely pathogenic |
Cerebral visual impairment and intellectual disability, Cerebral visual impairment and intellectual disability |
| RS755579580 |
TRPM1
|
Health Risk |
Pathogenic |
— |
| RS755580814 |
CPS1
|
Health Risk |
Likely pathogenic |
Congenital hyperammonemia, type I |
| RS755582766 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal spinal muscular atrophy 1, Charcot-Marie-Tooth disease axonal type 2S |
| RS755583135 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS755583250 |
FLNC
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS755584106 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Wilson disease |
| RS755585430 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS755585640 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755586334 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS755586631 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS755587601 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS755587950 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS755588045 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B3 |
| RS755589190 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Ullrich congenital muscular dystrophy 1A |
| RS755589533 |
SLC26A3
|
Health Risk |
Likely pathogenic |
— |
| RS755590047 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS755591790 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS755591829 |
FUS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Amyotrophic lateral sclerosis type 6 |
| RS755591966 |
CDK5RAP2
|
Health Risk |
Likely pathogenic |
— |
| RS75559353 |
CNNM4
|
Health Risk |
Pathogenic/Likely pathogenic |
Jalili syndrome, Jalili syndrome |
| RS755594972 |
CASK
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, CASK-related |
| RS755595060 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755595128 |
ERCC5
|
Health Risk |
Pathogenic |
— |
| RS755595256 |
PLPBP
|
Health Risk |
Pathogenic |
Epilepsy, early-onset |
| RS755595336 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755596079 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS755596256 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS755599243 |
RP1L1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 88, Retinitis pigmentosa 88 |
| RS755600323 |
ITGB2
|
Health Risk |
Pathogenic |
— |
| RS755601552 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS755601799 |
USH1C
|
Health Risk |
Pathogenic |
— |
| RS755601885 |
B3GAT3
|
Health Risk |
Pathogenic |
Larsen-like syndrome, B3GAT3 type |
| RS755604487 |
PHIP
|
Health Risk |
Likely pathogenic |
PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome, PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome |
| RS755604671 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinase-positive oculocutaneous albinism, SKIN/HAIR/EYE PIGMENTATION 1 |
| RS755607090 |
SETD5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755608387 |
CCBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hennekam lymphangiectasia-lymphedema syndrome 1, CCBE1-related disorder |
| RS755608537 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Inborn genetic diseases |
| RS755609198 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, CREBBP-related disorder |
| RS755609496 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS755610701 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755610740 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Ehlers-Danlos syndrome |
| RS755612674 |
G6PC1
|
Health Risk |
Pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Inborn genetic diseases |
| RS755613281 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS755613828 |
GSDME
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 5, GSDME-related disorder |
| RS755614529 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Sick sinus syndrome 2 |
| RS755615425 |
RIPK1
|
Health Risk |
Conflicting classifications of pathogenicity |
RIPK1-related disorder, Inborn genetic diseases |
| RS755616266 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS755619812 |
UNC13D
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS755620019 |
HLCS
|
Health Risk |
Conflicting classifications of pathogenicity |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS755620037 |
TSPAN12
|
Health Risk |
Pathogenic |
— |
| RS755620051 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS755621140 |
RDH12
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 13, Leber congenital amaurosis 13 |
| RS755622 |
MIF
|
Health Risk |
risk factor |
-, - |
| RS755622688 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS755623798 |
NUMA1
|
Health Risk |
Pathogenic |
Myoepithelial tumor, Myoepithelial tumor |
| RS755624074 |
SEC23B
|
Health Risk |
Likely pathogenic |
Congenital dyserythropoietic anemia, type II |
| RS755624411 |
MPV17
|
Health Risk |
Pathogenic |
— |
| RS755625628 |
CBS
|
Health Risk |
Pathogenic |
Classic homocystinuria, HYPERHOMOCYSTEINEMIA |
| RS755625888 |
EXT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Exostoses, multiple |
| RS755626994 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Telangiectasia, hereditary hemorrhagic |
| RS755627156 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, POLE-related disorder |
| RS755627444 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755628262 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755628334 |
SKIC3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755630903 |
SPTA1
|
Health Risk |
Pathogenic |
Hereditary spherocytosis type 3, Hereditary spherocytosis type 3 |
| RS755631456 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS755633330 |
FH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary leiomyomatosis and renal cell cancer |
| RS755634856 |
PIGG
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 53 |
| RS755634872 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS755635209 |
ARSA
|
Health Risk |
Pathogenic/Likely pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS755635372 |
GATAD2B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755635967 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS755635993 |
TGM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS755640019 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS755640269 |
PC
|
Health Risk |
Likely pathogenic |
Pyruvate carboxylase deficiency, Pyruvate carboxylase deficiency |
| RS755640305 |
IVD
|
Health Risk |
Conflicting classifications of pathogenicity |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS755640785 |
BCAT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypervalinemia and hyperleucine-isoleucinemia, Hypervalinemia and hyperleucine-isoleucinemia |
| RS755643283 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS755643402 |
LAMA2
|
Health Risk |
Pathogenic |
LAMA2-related muscular dystrophy, Merosin deficient congenital muscular dystrophy |
| RS755644971 |
MID1
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked Opitz G/BBB syndrome, X-linked Opitz G/BBB syndrome |
| RS755646290 |
USH2A
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 39, Retinitis pigmentosa 39 |
| RS755646665 |
TRMU
|
Health Risk |
Pathogenic/Likely pathogenic |
Aminoglycoside-induced deafness, Aminoglycoside-induced deafness |
| RS755646683 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual developmental disorder with autism and macrocephaly, Intellectual developmental disorder with autism and macrocephaly |
| RS755646937 |
TBK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Frontotemporal dementia and/or amyotrophic lateral sclerosis 4, Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 |
| RS755647054 |
MPV17
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755647308 |
ABCB11
|
Health Risk |
Pathogenic |
Benign recurrent intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS755648887 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Tetralogy of Fallot |
| RS755649235 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, COL4A4-related disorder |
| RS755649252 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS755650000 |
POMT2
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A2 |
| RS755651388 |
MICU1
|
Health Risk |
Pathogenic/Likely pathogenic |
MICU1-related disorder, Proximal myopathy with extrapyramidal signs |
| RS755651498 |
DYNC2H1
|
Health Risk |
Likely pathogenic |
Asphyxiating thoracic dystrophy 3, Asphyxiating thoracic dystrophy 3 |
| RS755651886 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS755653150 |
PANK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pigmentary pallidal degeneration, Hypoprebetalipoproteinemia |
| RS755653330 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS755653914 |
SCN9A
|
Health Risk |
Conflicting classifications of pathogenicity |
Channelopathy-associated congenital insensitivity to pain, autosomal recessive |
| RS755653922 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS755653950 |
NGLY1
|
Health Risk |
Pathogenic |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation |
| RS755654519 |
SLC2A10
|
Health Risk |
Conflicting classifications of pathogenicity |
Arterial tortuosity syndrome, Familial thoracic aortic aneurysm and aortic dissection |