| RS755898320 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Self-limited epilepsy with centrotemporal spikes, Developmental and epileptic encephalopathy 94 |
| RS755899326 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Magenis syndrome, Inborn genetic diseases |
| RS755900253 |
FHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked myopathy with postural muscle atrophy, Cardiovascular phenotype |
| RS755902927 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS755903123 |
TCTN3
|
Health Risk |
Pathogenic/Likely pathogenic |
Orofacial-digital syndrome IV, Joubert syndrome 18 |
| RS755904046 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Freeman-Sheldon syndrome, Distal arthrogryposis type 2B1 |
| RS755904252 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS755905226 |
ERCC6
|
Health Risk |
Likely pathogenic |
Cockayne syndrome type 2, Cockayne syndrome type 2 |
| RS755905249 |
TAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755906427 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS755907131 |
ETFDH
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS755908120 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS755908212 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 2, Inborn genetic diseases |
| RS755908331 |
USH1G
|
Health Risk |
Likely pathogenic |
— |
| RS755908353 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS755908721 |
GGCX
|
Health Risk |
Pathogenic |
— |
| RS755909523 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS755909719 |
RDH12
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 13, Leber congenital amaurosis 13 |
| RS755910254 |
CDH3
|
Health Risk |
Pathogenic |
— |
| RS755911247 |
BBS9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 9 |
| RS755911617 |
CCDC116
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755914063 |
DBT
|
Health Risk |
Pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 1A |
| RS755914340 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS755915465 |
SCN4B
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 10, Cardiovascular phenotype |
| RS755916316 |
WNT5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Robinow syndrome 1, Autosomal dominant Robinow syndrome 1 |
| RS755916513 |
TRPV6
|
Health Risk |
Likely pathogenic |
Hyperparathyroidism, transient neonatal |
| RS755918582 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS755919767 |
TREX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 1, Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations |
| RS755919784 |
SPTLC3
|
Health Risk |
Likely pathogenic |
Peripheral neuropathy, Sensory neuropathy |
| RS755920849 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Lynch syndrome 1 |
| RS755922032 |
TH
|
Health Risk |
Likely pathogenic |
Autosomal recessive DOPA responsive dystonia, Autosomal recessive DOPA responsive dystonia |
| RS755922289 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS755923652 |
CEP164
|
Health Risk |
Pathogenic |
Nephronophthisis 15, Nephronophthisis 15 |
| RS755923873 |
SLC17A5
|
Health Risk |
Pathogenic/Likely pathogenic |
Salla disease, SLC17A5-related disorder |
| RS755924637 |
KRT10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755924944 |
GRIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant |
| RS755924969 |
SMAD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aneurysm-osteoarthritis syndrome |
| RS755925068 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group A, Fanconi anemia |
| RS755925428 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755926095 |
GRHPR
|
Health Risk |
Likely pathogenic |
Primary hyperoxaluria, type II |
| RS755926439 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS755926856 |
CFH
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 4, CFH-Related Dense Deposit Disease / Membranoproliferative Glomerulonephritis Type II |
| RS755927061 |
COL4A4
|
Health Risk |
Likely pathogenic |
Autosomal recessive Alport syndrome, Hematuria |
| RS755927504 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Cardiovascular phenotype |
| RS755928019 |
SAR1B
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS755928079 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Woolly hair-skin fragility syndrome, Lethal acantholytic epidermolysis bullosa |
| RS755928543 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755928939 |
EPG5
|
Health Risk |
Likely pathogenic |
Vici syndrome, Inborn genetic diseases |
| RS755929725 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS755931396 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS755931555 |
SDCCAG8
|
Health Risk |
Conflicting classifications of pathogenicity |
Senior-Loken syndrome 7, Bardet-Biedl syndrome 16 |
| RS755931648 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome |
| RS755933716 |
ALG6
|
Health Risk |
Pathogenic/Likely pathogenic |
ALG6-congenital disorder of glycosylation 1C, ALG6-congenital disorder of glycosylation 1C |
| RS755933881 |
COQ8A
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Mitochondrial disease |
| RS755934816 |
PKLR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755934966 |
MYO7A
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 2, Usher syndrome type 1 |
| RS755935124 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS755935365 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS755935386 |
KIF1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Inborn genetic diseases |
| RS755936301 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontoneocerebellar hypoplasia, Pontocerebellar hypoplasia type 6 |
| RS755937050 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, DiGeorge syndrome |
| RS755937467 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, VPS13B-related disorder |
| RS755938406 |
FANCE
|
Health Risk |
Likely pathogenic |
Fanconi anemia, Fanconi anemia |
| RS755938967 |
IQCE
|
Health Risk |
Pathogenic |
Polydactyly, postaxial |
| RS755939422 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Kabuki syndrome 1 |
| RS755939601 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS755941834 |
RAG2
|
Health Risk |
Pathogenic |
Combined immunodeficiency with skin granulomas, Severe combined immunodeficiency |
| RS755941916 |
DHCR7
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS755943193 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS755943322 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755944287 |
CAD
|
Health Risk |
Pathogenic |
— |
| RS755944454 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS755944755 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS755945291 |
PEX5
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 2A (Zellweger), Peroxisome biogenesis disorder 2B |
| RS755946240 |
SMARCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755946598 |
PLPBP
|
Health Risk |
Pathogenic/Likely pathogenic |
Epilepsy, early-onset |
| RS755946631 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS755947203 |
FANCM
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS755947485 |
PEPD
|
Health Risk |
Pathogenic |
— |
| RS755947763 |
CYP11B2
|
Health Risk |
Likely pathogenic |
— |
| RS755947942 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa 25 |
| RS755948833 |
TG
|
Health Risk |
Conflicting classifications of pathogenicity |
Iodotyrosyl coupling defect, TG-related disorder |
| RS755948940 |
MVD
|
Health Risk |
Pathogenic |
Porokeratosis 7, multiple types |
| RS755949821 |
PRKG2
|
Health Risk |
Pathogenic |
— |
| RS755949982 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS755950154 |
PEX2
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder, Peroxisome biogenesis disorder 5A (Zellweger) |
| RS755950225 |
TBK1
|
Health Risk |
Pathogenic |
Frontotemporal dementia and/or amyotrophic lateral sclerosis 4, Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 |
| RS755950355 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS755950417 |
SRRM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755951235 |
SGSH
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS755952006 |
CBS
|
Health Risk |
Pathogenic/Likely pathogenic |
Classic homocystinuria, Homocystinuria |
| RS755952440 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CREBBP-related disorder |
| RS755954353 |
MTO1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency, Inborn genetic diseases |
| RS755954869 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, APC-related disorder |
| RS755955593 |
DOCK8
|
Health Risk |
Pathogenic |
— |
| RS755956494 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS755956613 |
SLC45A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculocutaneous albinism type 4, Oculocutaneous albinism type 4 |
| RS755958987 |
SPATA7
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Leber congenital amaurosis 3 |
| RS755959303 |
FLCN
|
Health Risk |
Likely pathogenic |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS755959403 |
CTSC
|
Health Risk |
Conflicting classifications of pathogenicity |
Haim-Munk syndrome, Papillon-Lefèvre syndrome |