| RS754892238 |
MADD
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS754892377 |
GNE
|
Health Risk |
Pathogenic/Likely pathogenic |
GNE myopathy, Sialuria |
| RS754893423 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Perry syndrome, Amyotrophic lateral sclerosis type 1 |
| RS754893576 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS754893727 |
ABCG5
|
Health Risk |
Likely pathogenic |
Sitosterolemia, Sitosterolemia |
| RS754893934 |
GRM6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754894257 |
MMAA
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria, cblA type |
| RS754895072 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS754895386 |
CHRNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 2A, Inborn genetic diseases |
| RS754895962 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS754896169 |
KCNQ3
|
Health Risk |
Conflicting classifications of pathogenicity |
Benign neonatal seizures, Benign neonatal seizures |
| RS754896795 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS754897911 |
TBX4
|
Health Risk |
Pathogenic/Likely pathogenic |
Pulmonary arterial hypertension associated with congenital heart disease, Pulmonary hypertension |
| RS754898479 |
ARSA
|
Health Risk |
Pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS754899711 |
ABCA4
|
Health Risk |
Pathogenic |
Stargardt disease, Retinitis pigmentosa |
| RS754900484 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS754901294 |
FXR1
|
Health Risk |
Likely pathogenic |
Intellectual disability, Intellectual disability |
| RS754901414 |
STT3B
|
Health Risk |
Conflicting classifications of pathogenicity |
STT3B-congenital disorder of glycosylation, STT3B-congenital disorder of glycosylation |
| RS754902005 |
SALL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Townes syndrome, Townes-Brocks syndrome 1 |
| RS754902598 |
UNC13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 3, Autoinflammatory syndrome |
| RS754903785 |
MUSK
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 9, Fetal akinesia deformation sequence 1 |
| RS754904956 |
ADA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of adenosine deaminase 2, Autoinflammatory syndrome |
| RS754906673 |
CCDC78
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy with internal nuclei and atypical cores, Inborn genetic diseases |
| RS754906806 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS754907965 |
DDX41
|
Health Risk |
Pathogenic |
DDX41-related hematologic malignancy predisposition syndrome, DDX41-related disorder |
| RS754908088 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754909135 |
ASPM
|
Health Risk |
Pathogenic |
Microcephaly 5, primary |
| RS754909198 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS754910706 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 5 |
| RS754911118 |
TTC21B
|
Health Risk |
Pathogenic/Likely pathogenic |
Asphyxiating thoracic dystrophy 4, Nephronophthisis 12 |
| RS754912569 |
ATP8B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 1, ATP8B1-related disorder |
| RS754912778 |
PKP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Arrhythmogenic right ventricular dysplasia 9, Arrhythmogenic right ventricular cardiomyopathy |
| RS754913230 |
FOXD4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754914260 |
DCC
|
Health Risk |
Pathogenic |
Mirror movements 1, Corpus callosum |
| RS754914420 |
ADCY3
|
Health Risk |
risk factor |
BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 19, BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 19 |
| RS754914807 |
PLCG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 3, Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation |
| RS754915138 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS754915287 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS754916169 |
MAK
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 62 |
| RS754916277 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754916421 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS754916822 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ovarian cancer |
| RS75491697 |
TNNI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS754917229 |
SAMHD1
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 5, Aicardi-Goutieres syndrome 5 |
| RS754917939 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS754919042 |
DYNC2H1
|
Health Risk |
Pathogenic/Likely pathogenic |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 3 |
| RS754919065 |
TRPC6
|
Health Risk |
Conflicting classifications of pathogenicity |
TRPC6-related disorder, Inborn genetic diseases |
| RS754919272 |
CHD3
|
Health Risk |
Pathogenic/Likely pathogenic |
Snijders Blok-Campeau syndrome, Intellectual disability |
| RS754919275 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS754919490 |
CYP4V2
|
Health Risk |
Pathogenic |
— |
| RS754921053 |
GRID1
|
Health Risk |
Pathogenic |
GRID1-associated neurodevelopmental disorder, GRID1-associated neurodevelopmental disorder |
| RS754921505 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS754921704 |
KCNH2
|
Health Risk |
Pathogenic |
Long QT syndrome, Long QT syndrome |
| RS754921908 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiomyopathy |
| RS754922174 |
TGM1
|
Health Risk |
Likely pathogenic |
— |
| RS754923656 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Alport syndrome |
| RS754924433 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Charcot-Marie-Tooth disease axonal type 2C |
| RS754924716 |
HFM1
|
Health Risk |
Likely pathogenic |
Premature ovarian failure 9, Premature ovarian failure 9 |
| RS754927479 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754928609 |
CHRNG
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive multiple pterygium syndrome |
| RS754928680 |
NPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Acromesomelic dysplasia 1, Maroteaux type |
| RS754929108 |
JARID2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS754929157 |
OTX2
|
Health Risk |
Pathogenic |
Anophthalmia-microphthalmia syndrome, Anophthalmia-microphthalmia syndrome |
| RS754929230 |
BRIP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS754929349 |
GP6
|
Health Risk |
Pathogenic |
Platelet-type bleeding disorder 11, Platelet-type bleeding disorder 11 |
| RS754929654 |
NIPBL
|
Health Risk |
Pathogenic |
— |
| RS754929718 |
KCNQ5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754930082 |
SLC35C1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukocyte adhesion deficiency type II, Leukocyte adhesion deficiency type II |
| RS754930340 |
LAMA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754930571 |
CAPN3
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS754930928 |
ASS1
|
Health Risk |
Likely pathogenic |
Citrullinemia, Citrullinemia type I |
| RS754930934 |
CDH23
|
Health Risk |
Likely pathogenic |
Pituitary adenoma 5, multiple types |
| RS754932150 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS754932526 |
AIRE
|
Health Risk |
Conflicting classifications of pathogenicity |
Polyglandular autoimmune syndrome, type 1 |
| RS754933794 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS754934987 |
BCS1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Pili torti-deafness syndrome, GRACILE syndrome |
| RS754935637 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS754936373 |
TRIP11
|
Health Risk |
Likely pathogenic |
Achondrogenesis, type IA |
| RS754936421 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS754937769 |
SKIC2
|
Health Risk |
Pathogenic |
— |
| RS754937863 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS754938068 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS754938191 |
PKD1
|
Health Risk |
Likely pathogenic |
Polycystic kidney disease, adult type |
| RS754938612 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Wilms tumor 1 |
| RS754938624 |
AMER1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754939638 |
PKLR
|
Health Risk |
Pathogenic |
Pyruvate kinase deficiency of red cells, PKLR-related disorder |
| RS754942883 |
HEXB
|
Health Risk |
Pathogenic |
Sandhoff disease, Sandhoff disease |
| RS754943076 |
SMARCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS754943606 |
C9
|
Health Risk |
Pathogenic |
— |
| RS754944119 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Polycystic kidney disease |
| RS754944359 |
AP4S1
|
Health Risk |
Pathogenic |
Spastic paraplegia, Hereditary spastic paraplegia 52 |
| RS754944429 |
AP4E1
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS754944605 |
WDR37
|
Health Risk |
Conflicting classifications of pathogenicity |
WDR37-related disorder, WDR37-related disorder |
| RS754944896 |
ABCG5
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Sitosterolemia 2 |
| RS754944912 |
DYNC2H1
|
Health Risk |
Pathogenic |
Asphyxiating thoracic dystrophy 3, Asphyxiating thoracic dystrophy 3 |
| RS754946168 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Nephronophthisis |
| RS754946422 |
CNGB3
|
Health Risk |
Pathogenic |
— |
| RS754948438 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS754948598 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS754949360 |
IDUA
|
Health Risk |
Pathogenic |
Hurler syndrome, Mucopolysaccharidosis type 1 |