| RS754824872 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS754825865 |
SLC34A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercalcemia, infantile |
| RS754826643 |
PFKM
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type VII |
| RS754826836 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypophosphatasia, Adult hypophosphatasia |
| RS754828592 |
SNAPC4
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with motor regression, progressive spastic paraplegia |
| RS754828716 |
BRAT1
|
Health Risk |
Likely pathogenic |
BRAT1-related neurodevelopmental disorder, BRAT1-related neurodevelopmental disorder |
| RS754828996 |
TAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class I deficiency, Inborn genetic diseases |
| RS754831415 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS754831666 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754832163 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa with pyloric atresia, Junctional epidermolysis bullosa with pyloric atresia |
| RS754833774 |
CELSR1
|
Health Risk |
Likely pathogenic |
Lymphatic malformation 9, Lymphatic malformation 9 |
| RS754833969 |
ACADM
|
Health Risk |
Pathogenic/Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS754834155 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2, Retinitis pigmentosa 39 |
| RS754834213 |
STRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754834282 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS754834466 |
CASQ2
|
Health Risk |
Pathogenic |
Catecholaminergic polymorphic ventricular tachycardia, Catecholaminergic polymorphic ventricular tachycardia |
| RS754836509 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS754836679 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS754837473 |
SRD5A3
|
Health Risk |
Conflicting classifications of pathogenicity |
SRD5A3-congenital disorder of glycosylation, Kahrizi syndrome |
| RS754837805 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS754838493 |
DICER1
|
Health Risk |
Likely pathogenic |
Pleuropulmonary blastoma, DICER1-related tumor predisposition |
| RS754840728 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS754841982 |
BLOC1S3
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome 8, Hermansky-Pudlak syndrome 8 |
| RS754842280 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hemorrhagic telangiectasia, Cardiovascular phenotype |
| RS754843093 |
COL5A2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, classic type |
| RS754844175 |
POLG
|
Health Risk |
Likely pathogenic |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS754847234 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS754847515 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS754848195 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Inborn genetic diseases |
| RS754848781 |
POLR1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754848806 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS754849177 |
TYRP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculocutaneous albinism type 3, Oculocutaneous albinism type 3 |
| RS754850404 |
FANCE
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS754850670 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy due to partial LAMA2 deficiency, LAMA2-related muscular dystrophy |
| RS754851037 |
CFI
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 13, Atypical hemolytic-uremic syndrome with I factor anomaly |
| RS754851778 |
EDA
|
Health Risk |
Pathogenic |
Hypohidrotic X-linked ectodermal dysplasia, Hypohidrotic X-linked ectodermal dysplasia |
| RS75485205 |
SLC2A1
|
Health Risk |
Pathogenic |
GLUT1 deficiency syndrome 1, autosomal recessive |
| RS754853149 |
ZBTB20
|
Health Risk |
Conflicting classifications of pathogenicity |
Primrose syndrome, Inborn genetic diseases |
| RS754853545 |
ADH5
|
Health Risk |
Pathogenic |
AMED syndrome, digenic |
| RS754854319 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS754854640 |
SLC11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcytic anemia with liver iron overload, SLC11A2-related disorder |
| RS754855090 |
LRPPRC
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type |
| RS754855261 |
CC2D1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754855677 |
PUS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Myopathy, lactic acidosis |
| RS754857276 |
BCAS3
|
Health Risk |
Pathogenic/Likely pathogenic |
Global developmental delay, Hengel-Maroofian-Schols syndrome |
| RS754858452 |
DNAAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 10, Primary ciliary dyskinesia |
| RS754858849 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754858999 |
GPC6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754859097 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Megacystis-microcolon-intestinal hypoperistalsis syndrome 1, Aortic aneurysm |
| RS754859909 |
MPL
|
Health Risk |
Pathogenic |
MPL-related disorder, Congenital amegakaryocytic thrombocytopenia |
| RS754861502 |
ILDR2
|
Health Risk |
Likely pathogenic |
Moyamoya angiopathy, Moyamoya angiopathy |
| RS754861924 |
KPTN
|
Health Risk |
Pathogenic |
Macrocephaly-developmental delay syndrome, Macrocephaly-developmental delay syndrome |
| RS754862360 |
NPHP4
|
Health Risk |
Pathogenic |
Nephronophthisis 4, Nephronophthisis |
| RS754862849 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Knobloch syndrome, Knobloch syndrome |
| RS754862975 |
DYNC2I2
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 11 with or without polydactyly, Short-rib thoracic dysplasia 11 with or without polydactyly |
| RS754863582 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754864849 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 7, Familial episodic pain syndrome with predominantly lower limb involvement |
| RS754865266 |
MYO15A
|
Health Risk |
Pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS754865465 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS754866098 |
ENPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypophosphatemic rickets, autosomal recessive |
| RS754866489 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS754867753 |
CCDC40
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 15 |
| RS754869116 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Boomerang dysplasia, Boomerang dysplasia |
| RS754869199 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754870679 |
TRIO
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754871147 |
SLC25A20
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine acylcarnitine translocase deficiency, Carnitine acylcarnitine translocase deficiency |
| RS754872251 |
SETD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS75487328 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1A |
| RS754873418 |
NDUFV2
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 7 |
| RS754873937 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS754874209 |
SNORD118
|
Health Risk |
Pathogenic |
Leukoencephalopathy with calcifications and cysts, Leukoencephalopathy with calcifications and cysts |
| RS754875934 |
HGSNAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 73, Mucopolysaccharidosis |
| RS754876029 |
CDH23
|
Health Risk |
Pathogenic |
Retinal dystrophy, Usher syndrome type 1D |
| RS754878801 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS754878991 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Familial hemiplegic migraine |
| RS754879198 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Endometrial carcinoma, Hereditary cancer-predisposing syndrome |
| RS754880269 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS754880999 |
CDH2
|
Health Risk |
Pathogenic |
Axon pathfinding, cardiac |
| RS754881125 |
QRSL1
|
Health Risk |
Likely pathogenic |
— |
| RS754881644 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754882266 |
UNC13D
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS754882710 |
PDLIM3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Primary dilated cardiomyopathy |
| RS754883449 |
TRNT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome, Retinitis pigmentosa and erythrocytic microcytosis |
| RS754883697 |
OTOG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754883792 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS754884110 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS754884716 |
GABRG2
|
Health Risk |
Conflicting classifications of pathogenicity |
EPILEPSY, CHILDHOOD ABSENCE |
| RS754885040 |
ARSL
|
Health Risk |
Likely pathogenic |
— |
| RS754885213 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS754885396 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS754885672 |
TGM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS75488587 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS754886335 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS754886562 |
DLL3
|
Health Risk |
Likely pathogenic |
— |
| RS754888145 |
POC1B
|
Health Risk |
Likely pathogenic |
— |
| RS754888410 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS754888606 |
DOCK6
|
Health Risk |
Likely pathogenic |
— |
| RS754889043 |
WASHC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 8, Ritscher-Schinzel syndrome |
| RS754889480 |
ANO5
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2L, Gnathodiaphyseal dysplasia |
| RS754890755 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Amyotrophic lateral sclerosis type 4 |