| RS755007390 |
ADA2
|
Health Risk |
Pathogenic |
Deficiency of adenosine deaminase 2, Deficiency of adenosine deaminase 2 |
| RS755007541 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS755007607 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS755007671 |
SFRP4
|
Health Risk |
Pathogenic |
Pyle metaphyseal dysplasia, Pyle metaphyseal dysplasia |
| RS755007999 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS755008774 |
PMM2
|
Health Risk |
Pathogenic/Likely pathogenic |
PMM2-congenital disorder of glycosylation, Inborn genetic diseases |
| RS755009242 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS755009745 |
NGLY1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation |
| RS755011754 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Late-infantile neuronal ceroid lipofuscinosis |
| RS755012183 |
ABCB4
|
Health Risk |
Pathogenic |
— |
| RS755012426 |
IL17RC
|
Health Risk |
Likely pathogenic |
Candidiasis, familial |
| RS755012990 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS755013078 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Sotos syndrome |
| RS755013341 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Complex neurodevelopmental disorder, Early-infantile DEE |
| RS755013836 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Gorlin syndrome |
| RS755014001 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS755014798 |
ACADSB
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of 2-methylbutyryl-CoA dehydrogenase, Deficiency of 2-methylbutyryl-CoA dehydrogenase |
| RS755017 |
ZBTB46
|
Health Risk |
association |
Chronic osteomyelitis, Chronic osteomyelitis |
| RS755017868 |
DHFR;MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS755018069 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS755021350 |
ATR
|
Health Risk |
Pathogenic |
— |
| RS755021367 |
NXF5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755022193 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS755022770 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755023434 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS755024172 |
DNAJC19
|
Health Risk |
Likely pathogenic |
3-methylglutaconic aciduria type 5, 3-methylglutaconic aciduria type 5 |
| RS755024692 |
ACO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Optic atrophy 9, Optic atrophy 9 |
| RS755025293 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS755026998 |
TRIO
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755028000 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS755028719 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS755029414 |
ALDH5A1
|
Health Risk |
Pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS755029735 |
BRPF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual developmental disorder with dysmorphic facies and ptosis, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS755031010 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome |
| RS755031341 |
DPYD
|
Health Risk |
Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS755032078 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 39 |
| RS755033580 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Hypercholesterolemia |
| RS755035387 |
LTBP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies |
| RS755035506 |
MBD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755036276 |
CNGB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 45, Retinitis pigmentosa 45 |
| RS755036513 |
FOXA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755038966 |
CC2D1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 3 |
| RS755039988 |
P3H2
|
Health Risk |
Pathogenic |
— |
| RS755040627 |
SLC6A5
|
Health Risk |
Pathogenic |
Hyperekplexia 3, Hyperekplexia 3 |
| RS755040883 |
TUBGCP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755041461 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 11 |
| RS755042147 |
MCOLN1
|
Health Risk |
Pathogenic |
Mucolipidosis type IV, Inborn genetic diseases |
| RS755043110 |
TANC2
|
Health Risk |
Pathogenic |
— |
| RS755043772 |
KMT2C
|
Health Risk |
Likely pathogenic |
— |
| RS755043901 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
COL2A1-related disorder, COL2A1-related disorder |
| RS755044609 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS755046298 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS755046558 |
APC
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS755047447 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Deafness |
| RS755047520 |
ZBTB18
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755047928 |
SDHD
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS755049614 |
SLC26A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis, type IB |
| RS755050703 |
MCM3AP
|
Health Risk |
Likely pathogenic |
Peripheral neuropathy, autosomal recessive |
| RS755053175 |
AQP2
|
Health Risk |
Likely pathogenic |
— |
| RS755053984 |
ASXL1
|
Health Risk |
Pathogenic |
— |
| RS755054282 |
GCDH
|
Health Risk |
Pathogenic |
Glutaric aciduria, type 1 |
| RS755054839 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS755055358 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Tuberous sclerosis syndrome |
| RS755056713 |
CACNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 4, Brugada syndrome 4 |
| RS755058199 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant COL1A2-related disorders, Ehlers-Danlos syndrome |
| RS755058452 |
COQ8A
|
Health Risk |
Pathogenic |
— |
| RS755058688 |
DPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature, Global developmental delay |
| RS755058802 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS755059628 |
RAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency, autosomal recessive |
| RS755060067 |
IFT122
|
Health Risk |
Conflicting classifications of pathogenicity |
Cranioectodermal dysplasia 1, Inborn genetic diseases |
| RS755060365 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS755060592 |
DNAI2
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS755061434 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiomyopathy |
| RS755064227 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 12, Retinal macular dystrophy type 2 |
| RS755064267 |
HADHB
|
Health Risk |
Pathogenic |
HADHB-related disorder, Mitochondrial trifunctional protein deficiency |
| RS755065532 |
PNPT1
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation defect type 13, Ovarian serous cystadenocarcinoma |
| RS755065651 |
MFN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease |
| RS755065800 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, King Denborough syndrome |
| RS755066542 |
CHD7
|
Health Risk |
Likely pathogenic |
CHARGE syndrome, CHARGE syndrome |
| RS755066600 |
ARID1A
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS755067397 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal acantholytic epidermolysis bullosa, Woolly hair-skin fragility syndrome |
| RS755067851 |
SCN9A
|
Health Risk |
Pathogenic/Likely pathogenic |
Generalized epilepsy with febrile seizures plus, type 7 |
| RS755067873 |
ARHGEF10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755068491 |
LGI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant epilepsy with auditory features, Inborn genetic diseases |
| RS755068898 |
C5
|
Health Risk |
Pathogenic |
— |
| RS755068980 |
FASTKD2
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex IV deficiency, nuclear type 1 |
| RS755069015 |
APC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS755069436 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS755069593 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS755071263 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS755073303 |
CASR
|
Health Risk |
Likely pathogenic |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS755073786 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS755074605 |
PTPRO
|
Health Risk |
Conflicting classifications of pathogenicity |
PTPRO-related disorder, Nephrotic syndrome |
| RS755075934 |
BRAT1
|
Health Risk |
Pathogenic |
Neonatal-onset encephalopathy with rigidity and seizures, Neonatal-onset encephalopathy with rigidity and seizures |
| RS755076586 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Arrhythmogenic right ventricular cardiomyopathy |
| RS755077681 |
MMUT
|
Health Risk |
Likely pathogenic |
Methylmalonic acidemia, Methylmalonic acidemia |
| RS755078197 |
UBE3A
|
Health Risk |
Pathogenic |
— |
| RS755079949 |
ARHGAP31
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755081153 |
AFF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755081246 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, DICER1-related tumor predisposition |