| RS754769591 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Progressive familial heart block type IB |
| RS754770911 |
ABCB4
|
Health Risk |
Likely pathogenic |
Progressive familial intrahepatic cholestasis type 3, Low phospholipid associated cholelithiasis |
| RS754771834 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, MYH9-related disorder |
| RS754771907 |
LRPPRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type |
| RS754772558 |
ALAS2
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked sideroblastic anemia 1, X-linked sideroblastic anemia 1 |
| RS754773453 |
CFAP300
|
Health Risk |
Pathogenic |
Ciliary dyskinesia, primary |
| RS754773488 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS754773665 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS754775337 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS754775447 |
PAFAH1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
VATER association, VATER association |
| RS754775789 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS754776389 |
DNAJB13
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 34, Primary ciliary dyskinesia 34 |
| RS754776552 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS754776767 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brittle cornea syndrome 1 |
| RS754777692 |
MTMR14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant centronuclear myopathy, Autosomal dominant centronuclear myopathy |
| RS754778750 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS754778907 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 10, Cardiomyopathy |
| RS754779102 |
FANCC
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS754779432 |
CTSC
|
Health Risk |
Pathogenic |
Periodontitis, aggressive 1 |
| RS754779853 |
SZT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 18 |
| RS754780894 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS754781119 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS75478217 |
CYB5R3
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of cytochrome-b5 reductase, Deficiency of cytochrome-b5 reductase |
| RS754782171 |
PLN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1P, Cardiovascular phenotype |
| RS754782740 |
CEP250
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754783287 |
TPRKB
|
Health Risk |
Likely pathogenic |
Galloway-Mowat syndrome 5, Galloway-Mowat syndrome 5 |
| RS754785410 |
DPYD
|
Health Risk |
Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS754785664 |
GANAB
|
Health Risk |
Pathogenic/Likely pathogenic |
Polycystic kidney disease 3 with or without polycystic liver disease, Polycystic kidney disease 3 with or without polycystic liver disease |
| RS754785708 |
F7
|
Health Risk |
Conflicting classifications of pathogenicity |
Factor VII deficiency, Congenital factor VII deficiency |
| RS754786301 |
CNGB1
|
Health Risk |
Pathogenic |
— |
| RS754786373 |
DMXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing loss, autosomal dominant 71 |
| RS754786846 |
SDCCAG8
|
Health Risk |
Conflicting classifications of pathogenicity |
Senior-Loken syndrome 7, Bardet-Biedl syndrome 16 |
| RS754788022 |
DLL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754788289 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754789952 |
BRAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal-onset encephalopathy with rigidity and seizures, Inborn genetic diseases |
| RS754790166 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS754790425 |
PEX16
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754791604 |
SLC2A1
|
Health Risk |
Pathogenic |
Encephalopathy due to GLUT1 deficiency, GLUT1 deficiency syndrome 1 |
| RS754791755 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754792792 |
BBS4
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, BBS4-related disorder |
| RS754792932 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS754793514 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS754793583 |
ZAP70
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to ZAP70 deficiency, Combined immunodeficiency due to ZAP70 deficiency |
| RS754794236 |
KCNH1
|
Health Risk |
Conflicting classifications of pathogenicity |
KCNH1 associated disorder, KCNH1 associated disorder |
| RS754794859 |
SLC19A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Biotin-responsive basal ganglia disease, Biotin-responsive basal ganglia disease |
| RS754795292 |
ETFDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS754797146 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS754797404 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS754797409 |
LAMC3
|
Health Risk |
Pathogenic |
— |
| RS754797599 |
FRAS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS754798297 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Tibial muscular dystrophy |
| RS754799308 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS754800464 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS754801098 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Blepharophimosis - intellectual disability syndrome |
| RS754802246 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
WFS1-Related Spectrum Disorders, Autosomal dominant nonsyndromic hearing loss 6 |
| RS754802510 |
HGD
|
Health Risk |
Pathogenic |
Alkaptonuria, Alkaptonuria |
| RS754804590 |
CNGB3
|
Health Risk |
Pathogenic |
— |
| RS754805158 |
ATP6V1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754805626 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS754805893 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy 1DD |
| RS754806477 |
KMT2B
|
Health Risk |
Pathogenic |
Dystonia 28, childhood-onset |
| RS754806883 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial melanoma |
| RS754808317 |
CIC
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754808508 |
PKHD1
|
Health Risk |
Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS754808908 |
PCARE
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS754809046 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Pulmonary fibrosis, Idiopathic Pulmonary Fibrosis |
| RS754809056 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754809715 |
RHO
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Congenital stationary night blindness autosomal dominant 1 |
| RS754809877 |
PRKN
|
Health Risk |
Pathogenic |
Autosomal recessive juvenile Parkinson disease 2, Lung cancer |
| RS754810094 |
PPP2R1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754810505 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS754810654 |
SPIDR
|
Health Risk |
Pathogenic |
Genetic non-acquired premature ovarian failure, Genetic non-acquired premature ovarian failure |
| RS754811291 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS754811534 |
BFSP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cataract 12 multiple types, Cataract 12 multiple types |
| RS754812284 |
WDR62
|
Health Risk |
Pathogenic |
— |
| RS75481239 |
CTSK
|
Health Risk |
Likely pathogenic |
Pyknodysostosis, Pyknodysostosis |
| RS754812742 |
FLG
|
Health Risk |
Pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS754813556 |
SUCLA2
|
Health Risk |
Likely pathogenic |
Mitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria |
| RS754813827 |
BMPER
|
Health Risk |
Conflicting classifications of pathogenicity |
Diaphanospondylodysostosis, Diaphanospondylodysostosis |
| RS754814123 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS754814477 |
RB1
|
Health Risk |
Pathogenic |
Retinoblastoma, Retinoblastoma |
| RS754814638 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS754815022 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS754815178 |
BACH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 60, Immunodeficiency 60 |
| RS754815179 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Myofibromatosis |
| RS754815235 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, Brugada syndrome 5 |
| RS754815286 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS754815317 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS754815893 |
ECHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency, Thymoma |
| RS754817283 |
PDX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 4, Pancreatic agenesis 1 |
| RS754818927 |
DICER1
|
Health Risk |
Pathogenic |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS754819005 |
BSND
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter syndrome, Bartter syndrome |
| RS754820097 |
POLR3A
|
Health Risk |
Likely pathogenic |
Neonatal pseudo-hydrocephalic progeroid syndrome, Leukodystrophy |
| RS754820584 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS754820795 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS754820811 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS754823057 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS754823810 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS754824181 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS754824568 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |