| RS754643632 |
ST3GAL5
|
Health Risk |
Pathogenic/Likely pathogenic |
GM3 synthase deficiency, GM3 synthase deficiency |
| RS754643779 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS754645078 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to CARD11 deficiency, BENTA disease |
| RS754645461 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS754645487 |
HTRA1
|
Health Risk |
Likely pathogenic |
— |
| RS754646220 |
ABCC2
|
Health Risk |
Pathogenic |
— |
| RS754646330 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS754646406 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS754646501 |
ACAD9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754646763 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RAI1-related disorder |
| RS754647491 |
AGPS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754647829 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS754648125 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, APC-Associated Polyposis Disorders |
| RS754649826 |
RINT1
|
Health Risk |
Pathogenic |
— |
| RS754650075 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS754650765 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754650766 |
UPF3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Syndromic X-linked intellectual disability 14 |
| RS754651519 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS754651566 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stickler syndrome, Inborn genetic diseases |
| RS754652044 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Lung cancer |
| RS754652471 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS754653320 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A3 |
| RS754653682 |
NPC1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type C1 |
| RS754653701 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS754654473 |
TYR
|
Health Risk |
Pathogenic/Likely pathogenic |
SKIN/HAIR/EYE PIGMENTATION 3, LIGHT/DARK SKIN |
| RS754654892 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS754655315 |
ITGA7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy due to integrin alpha-7 deficiency, Congenital muscular dystrophy due to integrin alpha-7 deficiency |
| RS754655363 |
CLN6
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis |
| RS754656023 |
NADK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive encephalopathy with leukodystrophy due to DECR deficiency, Bardet-Biedl syndrome 10 |
| RS754657555 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS754657948 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754658907 |
TG
|
Health Risk |
Pathogenic |
Autoimmune thyroid disease, susceptibility to |
| RS754659423 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, normal intelligence and immunodeficiency |
| RS754659441 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures |
| RS754659608 |
ENPP1
|
Health Risk |
Pathogenic/Likely pathogenic |
ENPP1-related disorder, ENPP1-related disorder |
| RS754659903 |
ASAH1
|
Health Risk |
Likely pathogenic |
ASAH1-related disorders, ASAH1-related disorders |
| RS754660381 |
CYP11B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glucocorticoid-remediable aldosteronism, Deficiency of steroid 11-beta-monooxygenase |
| RS754660432 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS75466054 |
CHAT
|
Health Risk |
Pathogenic |
Familial infantile myasthenia, Congenital myasthenic syndrome |
| RS754661359 |
TYR
|
Health Risk |
Pathogenic/Likely pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1B |
| RS754661378 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS754664476 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS754664563 |
PCCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Propionic acidemia, Propionic acidemia |
| RS754664923 |
TPM1
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Hypertrophic cardiomyopathy |
| RS754667036 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures, Inborn genetic diseases |
| RS754667407 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS754667801 |
ABCB6
|
Health Risk |
Pathogenic |
Familial pseudohyperkalemia, Familial pseudohyperkalemia |
| RS754668208 |
NIN
|
Health Risk |
Conflicting classifications of pathogenicity |
Seckel syndrome 7, Seckel syndrome 7 |
| RS754668472 |
GALC
|
Health Risk |
Pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS754668616 |
STXBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS754669149 |
COL4A4
|
Health Risk |
Likely pathogenic |
Autosomal recessive Alport syndrome, Hematuria |
| RS754671210 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy due to partial LAMA2 deficiency, LAMA2-related muscular dystrophy |
| RS754671742 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS754672490 |
ALG6
|
Health Risk |
Likely pathogenic |
ALG6-congenital disorder of glycosylation 1C, ALG6-congenital disorder of glycosylation 1C |
| RS754672983 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754673524 |
HADHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial trifunctional protein deficiency, Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency |
| RS754673606 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS754674622 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS754675590 |
FBN3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754675891 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS754675958 |
POP1
|
Health Risk |
Pathogenic |
— |
| RS754676104 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS754676663 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS754676727 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS754677943 |
SLC7A13
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754678956 |
LRPPRC
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754679070 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, autosomal dominant |
| RS754679651 |
XYLT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754680319 |
PSAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Metachromatic leukodystrophy, Sphingolipid activator protein 1 deficiency |
| RS754680848 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS754681578 |
TECTA
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS754682495 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS754683361 |
TUBB3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754683462 |
BSCL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Congenital generalized lipodystrophy type 2 |
| RS754684285 |
PEX6
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder, Heimler syndrome 2 |
| RS754684491 |
MAST1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754685052 |
LZTR1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS754686930 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS754687282 |
CC2D2A
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS754687998 |
WARS2
|
Health Risk |
Likely pathogenic |
— |
| RS754690619 |
RASGRP1
|
Health Risk |
Likely pathogenic |
— |
| RS754690894 |
ALMS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS754691019 |
LZTR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS754691182 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Inborn genetic diseases |
| RS754691867 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS754693143 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS754693386 |
GPR143
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754693395 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS754693509 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS754694089 |
BBS9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 9, Bardet-Biedl syndrome |
| RS75469429 |
GJC2
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 44, Hereditary spastic paraplegia 44 |
| RS754694815 |
DIO1
|
Health Risk |
Pathogenic |
Thyroid hormone metabolism, abnormal |
| RS754698253 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS754699043 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754699583 |
RPSA
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial isolated congenital asplenia, Familial isolated congenital asplenia |
| RS754699681 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Inborn genetic diseases |
| RS754699820 |
ITGA7
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital muscular dystrophy due to integrin alpha-7 deficiency, Congenital muscular dystrophy due to integrin alpha-7 deficiency |
| RS754700207 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS754701941 |
ALOXE3
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 3, Autosomal recessive congenital ichthyosis 3 |
| RS754702218 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |