| RS75365049 |
TOPAZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753650776 |
SGCA
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS753651666 |
CYP11B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of steroid 11-beta-monooxygenase, Glucocorticoid-remediable aldosteronism |
| RS753651742 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS753652169 |
CHAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome 4C, Familial infantile myasthenia |
| RS753654616 |
F9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary factor VIII deficiency disease, Hereditary factor IX deficiency disease |
| RS753654674 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS753655744 |
AHI1
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Joubert syndrome |
| RS753656246 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis syndrome |
| RS753656470 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Finnish congenital nephrotic syndrome, Focal segmental glomerulosclerosis |
| RS753656531 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS753657349 |
PRPH2
|
Health Risk |
Likely pathogenic |
Macular dystrophy, PRPH2-related disorder |
| RS753657631 |
GABRD
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Inborn genetic diseases |
| RS753658170 |
KCTD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy type 3, Progressive myoclonic epilepsy type 3 |
| RS753659298 |
GALNT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS753659345 |
DNAH1
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS753659619 |
BCAT2
|
Health Risk |
Pathogenic |
Hypervalinemia and hyperleucine-isoleucinemia, Hypervalinemia and hyperleucine-isoleucinemia |
| RS753659852 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Benign familial hematuria |
| RS753659949 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Neonatal severe primary hyperparathyroidism |
| RS753660142 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS753660549 |
TUBGCP6
|
Health Risk |
Likely pathogenic |
— |
| RS753660907 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Intrauterine growth retardation, metaphyseal dysplasia |
| RS753662262 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753662330 |
DMD
|
Health Risk |
Pathogenic/Likely pathogenic |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS753662982 |
DYNC2H1
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, DYNC2H1-related disorder |
| RS753663016 |
ERCC8
|
Health Risk |
Pathogenic |
— |
| RS753664074 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS753664225 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group J, Familial cancer of breast |
| RS753664726 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Brittle cornea syndrome 1, Cardiovascular phenotype |
| RS753665097 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS753665308 |
CPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital hyperammonemia, type I |
| RS753665968 |
SLC39A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, spondylocheirodysplastic type |
| RS753666055 |
ACD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 6 |
| RS753666447 |
NUP85
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753666460 |
SGSH
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS753666498 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS753666778 |
ANOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 1 with or without anosmia, Inborn genetic diseases |
| RS753667280 |
LRP2
|
Health Risk |
Likely pathogenic |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS753667370 |
ANO5
|
Health Risk |
Conflicting classifications of pathogenicity |
Gnathodiaphyseal dysplasia, Autosomal recessive limb-girdle muscular dystrophy type 2L |
| RS753667658 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753670246 |
NAGLU
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-B |
| RS753670589 |
IQCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753671152 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS753671672 |
CIT
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS753671880 |
ALDH7A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS753673450 |
RAD50
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS753673862 |
GABBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753674382 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Inborn genetic diseases |
| RS753674918 |
DCLRE1C
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency due to DCLRE1C deficiency, Severe combined immunodeficiency due to DCLRE1C deficiency |
| RS753675356 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS753675648 |
HNF4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 1, Familial hyperinsulinism |
| RS753676774 |
FGF23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypophosphatemic rickets, Tumoral calcinosis |
| RS753676934 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS753677011 |
RAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency with skin granulomas, Combined immunodeficiency with skin granulomas |
| RS753677285 |
CNTNAP1
|
Health Risk |
Pathogenic |
— |
| RS753677364 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS753677499 |
VIPAS39
|
Health Risk |
Pathogenic |
— |
| RS753677978 |
CA5A
|
Health Risk |
Pathogenic |
CA5A-related disorder, Hyperammonemic encephalopathy due to carbonic anhydrase VA deficiency |
| RS753679094 |
EVC
|
Health Risk |
Likely pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS753679234 |
BSCL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753679297 |
RNASEH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Aicardi-Goutieres syndrome 4, Inborn genetic diseases |
| RS753679568 |
MME
|
Health Risk |
Pathogenic |
— |
| RS753680111 |
ANKLE2
|
Health Risk |
Likely pathogenic |
Microcephaly 16, primary |
| RS753680242 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS753681184 |
SH3BP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibrous dysplasia of jaw, Inborn genetic diseases |
| RS753682653 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Autosomal recessive nonsyndromic hearing loss 4 |
| RS753683126 |
COL1A1
|
Health Risk |
Pathogenic |
Infantile cortical hyperostosis, Osteogenesis imperfecta |
| RS753683243 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS753685944 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS753686197 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS753686281 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS753686672 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS753686702 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS753687039 |
PDE6A
|
Health Risk |
Likely pathogenic |
— |
| RS753687060 |
PNPLA1
|
Health Risk |
Pathogenic |
Congenital ichthyosiform erythroderma, Autosomal recessive congenital ichthyosis 10 |
| RS753687760 |
TMC1
|
Health Risk |
Pathogenic |
Nonsyndromic genetic hearing loss, Nonsyndromic genetic hearing loss |
| RS753688167 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CREBBP-related disorder |
| RS753688777 |
MTSS2
|
Health Risk |
Pathogenic/Likely pathogenic |
MTSS2-related neurodevelopmental disorder, Intellectual developmental disorder with ocular anomalies and distinctive facial features |
| RS753690225 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Usher syndrome type 1F |
| RS753690348 |
NEUROD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Type 2 diabetes mellitus, Maturity-onset diabetes of the young type 6 |
| RS753690365 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS753691079 |
GDF5
|
Health Risk |
Pathogenic |
Brachydactyly type C, Brachydactyly type C |
| RS753691962 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KBG syndrome |
| RS753692696 |
SLC7A9
|
Health Risk |
Pathogenic |
Cystinuria, Cystinuria |
| RS753692812 |
CNGA3
|
Health Risk |
Likely pathogenic |
— |
| RS753694698 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753694760 |
TRDN
|
Health Risk |
Likely pathogenic |
TRDN-related disorder, TRDN-related disorder |
| RS753694905 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2K, Walker-Warburg congenital muscular dystrophy |
| RS753695099 |
MAN2B1
|
Health Risk |
Pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS753695101 |
RNASEH2A
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 4, Aicardi-Goutieres syndrome 4 |
| RS753695521 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Blepharophimosis - intellectual disability syndrome |
| RS753696173 |
ERCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebrooculofacioskeletal syndrome 2, Ovarian cancer |
| RS753696648 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS753696656 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS753696924 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS753697730 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS753697847 |
SPATA7
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 3, Retinitis pigmentosa 94 |
| RS753698250 |
BCKDHA
|
Health Risk |
Pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 1A |
| RS753698480 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS753698911 |
ASH1L
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |