| RS753820400 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS753823218 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, Peroxisome biogenesis disorder 1A (Zellweger) |
| RS753823851 |
ALDH18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Cutis laxa |
| RS753823903 |
HEXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Sandhoff disease, Sandhoff disease |
| RS753824369 |
COA8
|
Health Risk |
Likely pathogenic |
Mitochondrial complex IV deficiency, nuclear type 17 |
| RS753824435 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS753824908 |
COL18A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Knobloch syndrome 1, Knobloch syndrome 1 |
| RS753825335 |
D2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
D-2-hydroxyglutaric aciduria 1, D-2-hydroxyglutaric aciduria 1 |
| RS753826693 |
CNTN1
|
Health Risk |
Likely pathogenic |
— |
| RS753827372 |
POMGNT1
|
Health Risk |
Pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B3 |
| RS753828284 |
CHRNE
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 4C, Congenital myasthenic syndrome 4A |
| RS753828779 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS753829097 |
ARG1
|
Health Risk |
Pathogenic/Likely pathogenic |
Arginase deficiency, ARG1-related disorder |
| RS753829320 |
MFF
|
Health Risk |
Pathogenic |
Encephalopathy due to defective mitochondrial and peroxisomal fission 2, Encephalopathy due to defective mitochondrial and peroxisomal fission 2 |
| RS753829354 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS753829743 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS753829876 |
KCNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 32 |
| RS753831049 |
CFB
|
Health Risk |
Conflicting classifications of pathogenicity |
Macular degeneration, Atypical hemolytic-uremic syndrome with B factor anomaly |
| RS753831132 |
DNAH8
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Spermatogenic failure 46 |
| RS753831464 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS753831692 |
FRAS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fraser syndrome 1, Cryptophthalmos syndrome |
| RS753832760 |
PLCB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 12 |
| RS753832779 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1F, Usher syndrome type 1F |
| RS753833996 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Polycystic kidney disease |
| RS753835568 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS753835841 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS753837544 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS753838459 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS753839004 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS753839301 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS753839890 |
MPI
|
Health Risk |
Pathogenic/Likely pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS753840283 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS753841103 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753841404 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
A2ML1-related disorder, Noonan syndrome |
| RS753843872 |
FAM20C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753843962 |
HNF4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 1, Familial hyperinsulinism |
| RS753844157 |
DISP1
|
Health Risk |
Conflicting classifications of pathogenicity |
DISP1-related disorder, DISP1-related disorder |
| RS753844400 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS753844954 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS753845247 |
SLC34A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercalcemia, infantile |
| RS753845990 |
BBS2
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 2, Bardet-Biedl syndrome 2 |
| RS753846865 |
HYCC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelination and Congenital Cataract, Hypomyelination and Congenital Cataract |
| RS753847783 |
HNF1B
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Maturity-onset diabetes of the young, HNF1B-related disorder |
| RS753849540 |
SPTA1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS753849847 |
RLBP1
|
Health Risk |
Pathogenic |
— |
| RS753850419 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS753850577 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS753850982 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiovascular phenotype |
| RS753851892 |
ENPP1
|
Health Risk |
Likely pathogenic |
Arterial calcification, generalized |
| RS753852308 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS753853134 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, 7 conditions |
| RS753853386 |
ABHD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Triglyceride storage disease with ichthyosis, Triglyceride storage disease with ichthyosis |
| RS753853752 |
SEMA4A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753854351 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS753854812 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS753855163 |
ADA
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency, autosomal recessive |
| RS753855245 |
MMACHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cobalamin C disease, Cobalamin C disease |
| RS753855393 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS753856820 |
POMC
|
Health Risk |
Pathogenic |
Obesity due to pro-opiomelanocortin deficiency, Obesity |
| RS753857000 |
ZFYVE26
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 15, Hereditary spastic paraplegia 15 |
| RS753857146 |
PRX
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease type 4 |
| RS753857234 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, DICER1-related tumor predisposition |
| RS753857355 |
GK
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS753857795 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS753858167 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753858988 |
FBN1
|
Health Risk |
Pathogenic |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS753859207 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS753859240 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS753859556 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Cardiovascular phenotype |
| RS753859758 |
CARD14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Pityriasis rubra pilaris |
| RS753861836 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS753862052 |
RAD51D
|
Health Risk |
Pathogenic/Likely pathogenic |
Breast-ovarian cancer, familial |
| RS753862254 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753862598 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS753862749 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS753865441 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS753865718 |
ATP2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Brody myopathy, Brody myopathy |
| RS753866114 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753866301 |
TRIM32
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Sarcotubular myopathy |
| RS753866423 |
OPHN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753866885 |
CC2D1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 3 |
| RS753867828 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, COL4A2-related disorder |
| RS753868549 |
SMARCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Blepharophimosis-impaired intellectual development syndrome |
| RS753869048 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS753870000 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS753870010 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS753870656 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS753871454 |
ASPA
|
Health Risk |
Pathogenic |
Spongy degeneration of central nervous system, Canavan Disease |
| RS753872402 |
ARSA
|
Health Risk |
Pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS753873681 |
NDUFAF6
|
Health Risk |
Pathogenic/Likely pathogenic |
Leigh syndrome, Mitochondrial complex I deficiency |
| RS753874439 |
RMRP
|
Health Risk |
Likely pathogenic |
Anauxetic dysplasia, Metaphyseal chondrodysplasia |
| RS753874848 |
PLA2G6
|
Health Risk |
Pathogenic/Likely pathogenic |
PLA2G6-associated neurodegeneration, Infantile neuroaxonal dystrophy |
| RS753874898 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome 3, Joubert syndrome |
| RS753874904 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753875871 |
ROR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Brachydactyly type B1, Autosomal recessive Robinow syndrome |
| RS753875974 |
SMAD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aneurysm-osteoarthritis syndrome |
| RS753876000 |
DVL3
|
Health Risk |
Likely pathogenic |
11 conditions, 11 conditions |
| RS753876598 |
CETP
|
Health Risk |
Pathogenic |
— |
| RS753877293 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753878222 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |