| RS753935209 |
COL18A1
|
Health Risk |
Likely pathogenic |
Knobloch syndrome, Knobloch syndrome |
| RS753935319 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS753935388 |
KIDINS220
|
Health Risk |
Conflicting classifications of pathogenicity |
KIDINS220-related disorder, Inborn genetic diseases |
| RS753935822 |
FCHO1
|
Health Risk |
Likely pathogenic |
— |
| RS753938407 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS753938507 |
IFT27
|
Health Risk |
Conflicting classifications of pathogenicity |
IFT27-related disorder, Inborn genetic diseases |
| RS753942596 |
PDE6A
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Inborn genetic diseases |
| RS753942853 |
MEN1
|
Health Risk |
Likely pathogenic |
Multiple endocrine neoplasia, type 1 |
| RS753943393 |
POLR3B
|
Health Risk |
Pathogenic |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Familial cancer of breast |
| RS753943702 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia type 4 |
| RS753944130 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS753945261 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Autosomal recessive Alport syndrome |
| RS753945728 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS753946523 |
VAMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753947354 |
CIITA
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class II deficiency, Inborn genetic diseases |
| RS753947379 |
MTRR
|
Health Risk |
Conflicting classifications of pathogenicity |
Disorders of Intracellular Cobalamin Metabolism, Methylcobalamin deficiency type cblE |
| RS753947676 |
GARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS753948138 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency, EP300-related disorder |
| RS753948488 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS753948557 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, FG syndrome |
| RS753948675 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS753949204 |
KCNJ1
|
Health Risk |
Pathogenic/Likely pathogenic |
Bartter syndrome, Bartter disease type 2 |
| RS753950471 |
DDHD2
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 54, Hereditary spastic paraplegia 54 |
| RS753950483 |
RAD50
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS753950967 |
DST
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 6, Epidermolysis bullosa simplex 3 |
| RS753952200 |
SGCD
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2F, Inborn genetic diseases |
| RS753952757 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to CARD11 deficiency, BENTA disease |
| RS753953146 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS753953205 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS753953732 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiac arrhythmia |
| RS753954220 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS753954585 |
CAMTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753955326 |
FANCG
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group G |
| RS753955773 |
ROBO4
|
Health Risk |
Likely pathogenic |
— |
| RS753956374 |
SPG7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS753956513 |
SLC6A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperekplexia 3, Hyperekplexia 3 |
| RS753956759 |
DNAJC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, DNAJC5-related disorder |
| RS753957126 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS753958013 |
SACS
|
Health Risk |
Pathogenic/Likely pathogenic |
Charlevoix-Saguenay spastic ataxia, Charlevoix-Saguenay spastic ataxia |
| RS753958204 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS753959620 |
CAV3
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS753959716 |
RDH12
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 13, Leber congenital amaurosis |
| RS753960106 |
FRAS1
|
Health Risk |
Pathogenic |
— |
| RS753960624 |
DHCR7
|
Health Risk |
Pathogenic/Likely pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS753960738 |
TRIM32
|
Health Risk |
Conflicting classifications of pathogenicity |
TRIM32-related disorder, Bardet-Biedl syndrome |
| RS753960777 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS753961140 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753961188 |
ATM
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS753961343 |
PC
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate carboxylase deficiency, Pyruvate carboxylase deficiency |
| RS753962912 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Spastic ataxia |
| RS753964516 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS753965226 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
GM1 gangliosidosis type 3, Mucopolysaccharidosis |
| RS753965584 |
MTHFD1
|
Health Risk |
Pathogenic |
— |
| RS753965618 |
SLC12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 1, Bartter disease type 1 |
| RS753965650 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS753965718 |
ELANE
|
Health Risk |
Conflicting classifications of pathogenicity |
Cyclical neutropenia, Neutropenia |
| RS753965947 |
ATP8B1
|
Health Risk |
Pathogenic |
Benign recurrent intrahepatic cholestasis type 1, Benign recurrent intrahepatic cholestasis type 1 |
| RS753965951 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS753966040 |
OPTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Amyotrophic lateral sclerosis type 12, Glaucoma 1 |
| RS753966526 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Tip-toe gait |
| RS753966916 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753966933 |
RAB27A
|
Health Risk |
Pathogenic/Likely pathogenic |
Griscelli syndrome type 2, Autoinflammatory syndrome |
| RS753967999 |
PHIP
|
Health Risk |
Conflicting classifications of pathogenicity |
PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome, PHIP-related disorder |
| RS753968550 |
CHEK2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS753968560 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753970789 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS753971115 |
ARSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Chondrodysplasia punctata |
| RS753972711 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS753972832 |
COL4A6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753973135 |
EXT2
|
Health Risk |
Likely pathogenic |
Exostoses, multiple |
| RS753973474 |
BLM
|
Health Risk |
Pathogenic |
Bloom syndrome, Bloom syndrome |
| RS753974933 |
PLCG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 3, Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation |
| RS753975649 |
ADCY5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753976233 |
F2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital prothrombin deficiency, Thrombophilia due to thrombin defect |
| RS753977266 |
HRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Costello syndrome, HRAS-related disorder |
| RS753977426 |
MYO5B
|
Health Risk |
Pathogenic |
— |
| RS753978592 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hennekam lymphangiectasia-lymphedema syndrome 2, Van Maldergem syndrome 2 |
| RS753978859 |
UGT2B17
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753979060 |
TUBB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753980264 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS753980616 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS753980727 |
SLC2A2
|
Health Risk |
Pathogenic |
Fanconi-Bickel syndrome, Fanconi-Bickel syndrome |
| RS753981900 |
PCCB
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |
| RS753981913 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, Cardiovascular phenotype |
| RS753983449 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS753984036 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS753984170 |
COL18A1
|
Health Risk |
Likely pathogenic |
Hereditary glaucoma, primary closed-angle |
| RS753984595 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS753985914 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive nonsyndromic hearing loss 12 |
| RS75398746 |
POF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Premature ovarian failure 2B, Premature ovarian insufficiency |
| RS753989803 |
ZFYVE19
|
Health Risk |
Pathogenic |
Cholestasis, progressive familial intrahepatic |
| RS753989899 |
COL4A1
|
Health Risk |
Likely pathogenic |
Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome, Hemorrhage |
| RS753989925 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Inborn genetic diseases |
| RS75398993 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Kidney disorder |
| RS753990040 |
UNC13D
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS753990994 |
SAG
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Oguchi disease |
| RS753991568 |
CHM
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS753993081 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS753993842 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS753993867 |
GLIS3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal diabetes mellitus with congenital hypothyroidism, Neonatal diabetes mellitus with congenital hypothyroidism |