| RS754064567 |
MYPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1KK |
| RS754064981 |
CDT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754065526 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS754066841 |
MKKS
|
Health Risk |
Pathogenic/Likely pathogenic |
McKusick-Kaufman syndrome, Bardet-Biedl syndrome |
| RS754066881 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS754067214 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 12 |
| RS754067988 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754068936 |
MPZ
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, Charcot-Marie-Tooth disease |
| RS754069091 |
SUMF1
|
Health Risk |
Pathogenic |
Multiple sulfatase deficiency, Multiple sulfatase deficiency |
| RS754069818 |
HARS2
|
Health Risk |
Likely pathogenic |
Perrault syndrome 2, Perrault syndrome 2 |
| RS754070045 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, MEGF10-related myopathy |
| RS754070093 |
CDC73
|
Health Risk |
Conflicting classifications of pathogenicity |
Parathyroid carcinoma, Hereditary cancer-predisposing syndrome |
| RS754072174 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754074166 |
PURA
|
Health Risk |
Conflicting classifications of pathogenicity |
PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome, Inborn genetic diseases |
| RS754075625 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, 7 conditions |
| RS754075778 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Knobloch syndrome, Knobloch syndrome 1 |
| RS754075911 |
USH2A
|
Health Risk |
Likely pathogenic |
— |
| RS754076425 |
PJVK
|
Health Risk |
Pathogenic |
— |
| RS754076573 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS754077128 |
GLB1
|
Health Risk |
Conflicting classifications of pathogenicity |
GM1 gangliosidosis type 2, Mucopolysaccharidosis |
| RS754078574 |
AAAS
|
Health Risk |
Pathogenic |
Glucocorticoid deficiency with achalasia, Glucocorticoid deficiency with achalasia |
| RS754079962 |
PRF1
|
Health Risk |
Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Familial hemophagocytic lymphohistiocytosis |
| RS754080445 |
CDC45
|
Health Risk |
Likely pathogenic |
Meier-Gorlin syndrome 7, Meier-Gorlin syndrome 7 |
| RS754081311 |
FKTN
|
Health Risk |
Pathogenic |
Walker-Warburg congenital muscular dystrophy, Walker-Warburg congenital muscular dystrophy |
| RS754081544 |
TWNK
|
Health Risk |
Conflicting classifications of pathogenicity |
Perrault syndrome 5, Perrault syndrome 5 |
| RS754081635 |
DICER1
|
Health Risk |
Pathogenic |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS754081921 |
PRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease |
| RS754082348 |
ETFDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS754082669 |
ABCA4
|
Health Risk |
Likely pathogenic |
Severe early-childhood-onset retinal dystrophy, Severe early-childhood-onset retinal dystrophy |
| RS754085928 |
COL4A3
|
Health Risk |
Pathogenic |
Autosomal dominant Alport syndrome, COL4A3-related disorder |
| RS754086671 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS754086897 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS754087173 |
CHRND
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal multiple pterygium syndrome, Lethal multiple pterygium syndrome |
| RS754087233 |
ARL2BP
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS754087775 |
F11
|
Health Risk |
Likely pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS754087904 |
ASPA
|
Health Risk |
Likely pathogenic |
Spongy degeneration of central nervous system, Canavan Disease |
| RS754088416 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS754088610 |
ABCA4
|
Health Risk |
Pathogenic |
Isolated macular dystrophy, Isolated macular dystrophy |
| RS754088992 |
EYA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1J |
| RS754090538 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS754090711 |
WFS1
|
Health Risk |
Likely pathogenic |
— |
| RS754091712 |
IFT80
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS754092059 |
PTPRC
|
Health Risk |
Likely pathogenic |
Immunodeficiency 105, Immunodeficiency 105 |
| RS754092062 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS754094260 |
ADCY10
|
Health Risk |
Likely pathogenic |
Familial idiopathic hypercalciuria, Familial idiopathic hypercalciuria |
| RS754096545 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS754097253 |
DHTKD1
|
Health Risk |
Likely pathogenic |
2-aminoadipic 2-oxoadipic aciduria, 2-aminoadipic 2-oxoadipic aciduria |
| RS754097557 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal myopathy with posterior leg and anterior hand involvement, Hypertrophic cardiomyopathy 26 |
| RS754097561 |
MCOLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucolipidosis type IV, Inborn genetic diseases |
| RS754097967 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS754099015 |
WDR73
|
Health Risk |
Pathogenic |
Galloway-Mowat syndrome 1, Galloway-Mowat syndrome 1 |
| RS754100023 |
BMP1
|
Health Risk |
Likely pathogenic |
— |
| RS754100176 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS754100363 |
KIZ
|
Health Risk |
Pathogenic |
— |
| RS754101639 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS754101758 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS754104046 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS754104059 |
F5
|
Health Risk |
Conflicting classifications of pathogenicity |
Factor V deficiency, Ischemic stroke |
| RS754104546 |
MYO7A
|
Health Risk |
Likely pathogenic |
— |
| RS754104695 |
MYH2
|
Health Risk |
Likely pathogenic |
Myopathy, proximal |
| RS754104931 |
USH2A
|
Health Risk |
Pathogenic |
— |
| RS754106837 |
PPP2R3C
|
Health Risk |
Pathogenic |
Gonadal dysgenesis, dysmorphic facies |
| RS754107444 |
MAN1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rafiq syndrome, Rafiq syndrome |
| RS754108525 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS754109027 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS754109115 |
F11
|
Health Risk |
Likely pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS754109868 |
DPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of glycosylation type 1E, Congenital disorder of glycosylation type 1E |
| RS754111466 |
TRPS1
|
Health Risk |
Likely pathogenic |
— |
| RS754113666 |
CNOT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754115924 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy |
| RS754116386 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS754116867 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS754119978 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS754120044 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS754120063 |
SLC2A10
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial aortopathy, Familial aortopathy |
| RS754121141 |
MARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754121148 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, Charcot-Marie-Tooth disease type 2 |
| RS754121759 |
EXOSC9
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS754121842 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754122018 |
APC
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial multiple polyposis syndrome |
| RS754122699 |
LAMC3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754124986 |
LIPA
|
Health Risk |
Likely pathogenic |
Lysosomal acid lipase deficiency, Lysosomal acid lipase deficiency |
| RS754125407 |
ADAMTSL4
|
Health Risk |
Pathogenic/Likely pathogenic |
Isolated ectopia lentis, Isolated ectopia lentis |
| RS754126406 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS754126557 |
GH1
|
Health Risk |
Likely pathogenic |
Autosomal dominant isolated somatotropin deficiency, Autosomal dominant isolated somatotropin deficiency |
| RS754126755 |
CTRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS754127386 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Lethal acantholytic epidermolysis bullosa |
| RS754128155 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS754128910 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Blepharophimosis - intellectual disability syndrome |
| RS754129466 |
ASXL1
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Rubinstein Taybi like syndrome |
| RS754130052 |
SUN5
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 16, Spermatogenic failure 16 |
| RS754130942 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, Peroxisome biogenesis disorder 1B |
| RS754131049 |
USH2A
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 39, Retinitis pigmentosa 39 |
| RS754131566 |
GLB1
|
Health Risk |
Pathogenic |
Infantile GM1 gangliosidosis, GM1 gangliosidosis type 3 |
| RS754133410 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS754133577 |
DSG2
|
Health Risk |
Pathogenic |
Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy |
| RS754133842 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS754134498 |
OTOGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 84B, Autosomal recessive nonsyndromic hearing loss 84B |
| RS754134578 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS754135389 |
AFG2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome, AFG2A-related disorder |