| RS753759723 |
GLDC
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS753759904 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS753760095 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS753761094 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS753761607 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, 7 conditions |
| RS753761683 |
GNAT1
|
Health Risk |
Pathogenic |
— |
| RS753762300 |
UNC13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis |
| RS75376282 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Diabetes mellitus, transient neonatal |
| RS753763148 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS753763495 |
CEP120
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 13 with or without polydactyly, Inborn genetic diseases |
| RS753764275 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS753767193 |
TBC1D24
|
Health Risk |
Pathogenic |
Autosomal dominant nonsyndromic hearing loss 65, Developmental and epileptic encephalopathy |
| RS753767237 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS753767582 |
ABRAXAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753767675 |
IDUA
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis |
| RS753767897 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS753768072 |
GP1BA
|
Health Risk |
Pathogenic |
Bernard Soulier syndrome, Bernard Soulier syndrome |
| RS753768576 |
NPC1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type C1 |
| RS753768741 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, PRDM5-related disorder |
| RS753768766 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753769576 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS753769799 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyropoikilocytosis, hereditary |
| RS753770061 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 9, Meckel syndrome |
| RS753770252 |
VPS13B
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Cohen syndrome |
| RS753771532 |
DNAH1
|
Health Risk |
Pathogenic |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS753773546 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS753774484 |
CYP11B1
|
Health Risk |
Likely pathogenic |
Deficiency of steroid 11-beta-monooxygenase, Congenital adrenal hyperplasia |
| RS75377471 |
PEX10
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 6A (Zellweger), Peroxisome biogenesis disorder |
| RS753774833 |
NPHP4
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS753774853 |
SELENON
|
Health Risk |
Conflicting classifications of pathogenicity |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS753775062 |
FKBP14
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type |
| RS753775083 |
PEPD
|
Health Risk |
Pathogenic |
— |
| RS753776168 |
ZIC2
|
Health Risk |
Pathogenic |
— |
| RS753776182 |
FOLR1
|
Health Risk |
Pathogenic |
Cerebral folate transport deficiency, Cerebral folate transport deficiency |
| RS753776329 |
CNGB1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 45, Retinitis pigmentosa 45 |
| RS753776604 |
CPT1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 1A deficiency |
| RS753778809 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS753779965 |
SCO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardioencephalomyopathy, fatal infantile |
| RS753780084 |
DPM1
|
Health Risk |
Pathogenic |
Congenital disorder of glycosylation type 1E, Malignant tumor of urinary bladder |
| RS753780877 |
HERC1
|
Health Risk |
Pathogenic |
Megalencephaly with thick corpus callosum, cerebellar atrophy |
| RS753782098 |
TARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753782715 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS753785426 |
COCH
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 9, Autosomal dominant nonsyndromic hearing loss 9 |
| RS753785671 |
BARD1
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS753785719 |
B9D1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS753786462 |
BCOR
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculofaciocardiodental syndrome, BCOR-related disorder |
| RS753787033 |
HPDL
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities, Spastic paraplegia |
| RS753787975 |
TALDO1
|
Health Risk |
Likely pathogenic |
Deficiency of transaldolase, TALDO1-related disorder |
| RS753788498 |
HARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 3B, Usher syndrome type 3B |
| RS753789459 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS753790195 |
F10
|
Health Risk |
Pathogenic |
Factor X deficiency, Factor X deficiency |
| RS753790346 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 3 |
| RS753791074 |
CD36
|
Health Risk |
Likely pathogenic |
CD36-related disorder, Platelet-type bleeding disorder 10 |
| RS753791198 |
CPLANE1
|
Health Risk |
Likely pathogenic |
Joubert syndrome 17, Joubert syndrome 17 |
| RS753792077 |
ZFYVE26
|
Health Risk |
Likely pathogenic |
— |
| RS753792152 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS753793346 |
HCN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753793522 |
ECHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency, Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency |
| RS753794138 |
DNMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory neuropathy-deafness-dementia syndrome, Inborn genetic diseases |
| RS753794696 |
MPDZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753794752 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS753795563 |
DYRK1A
|
Health Risk |
Pathogenic/Likely pathogenic |
DYRK1A-related intellectual disability syndrome, DYRK1A-related disorder |
| RS753795627 |
GCK
|
Health Risk |
Likely pathogenic |
Maturity-onset diabetes of the young type 2, Maturity-onset diabetes of the young type 1 |
| RS753796180 |
LIPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Wolman disease, Cholesteryl ester storage disease |
| RS753796271 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colon cancer |
| RS753797445 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS753798236 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS753798494 |
TGM1
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS753798870 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS753800840 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 2, primary |
| RS753801146 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS753801611 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 2, Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 2 |
| RS753802322 |
TBK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe SARS-CoV-2 infection, susceptibility to |
| RS753802842 |
DYNC2I2
|
Health Risk |
Pathogenic/Likely pathogenic |
Short-rib thoracic dysplasia 11 with or without polydactyly, Short-rib thoracic dysplasia 11 with or without polydactyly |
| RS753803330 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS753803615 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753803790 |
SZT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 18 |
| RS753803824 |
AXIN2
|
Health Risk |
Pathogenic |
Oligodontia-cancer predisposition syndrome, Oligodontia-cancer predisposition syndrome |
| RS753804000 |
HPS6
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome 6, Hermansky-Pudlak syndrome 6 |
| RS753804023 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS753804606 |
ZEB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mowat-Wilson syndrome, Mowat-Wilson syndrome |
| RS753805537 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS753806117 |
STAT2
|
Health Risk |
Pathogenic |
Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection, Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection |
| RS753806649 |
LDLRAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS753807100 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glomerulopathy with fibronectin deposits 2, Spondylometaphyseal dysplasia - Sutcliffe type |
| RS753808755 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS753810197 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS75381106 |
CIITA
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class II deficiency, MHC class II deficiency |
| RS753811189 |
FKRP
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2I, Autosomal recessive limb-girdle muscular dystrophy type 2I |
| RS753811883 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS753812499 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS753812859 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS753816420 |
MOCS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type B, Sulfite oxidase deficiency due to molybdenum cofactor deficiency type B |
| RS753816946 |
ACAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS753817458 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS753818473 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome, Brain small vessel disease 1 with or without ocular anomalies |
| RS75381894 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS753818949 |
COL4A4
|
Health Risk |
Pathogenic |
Autosomal recessive Alport syndrome, Autosomal recessive Alport syndrome |
| RS753819164 |
COL7A1
|
Health Risk |
Pathogenic |
Recessive dystrophic epidermolysis bullosa, Recessive dystrophic epidermolysis bullosa |
| RS753819738 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis type II, Achondrogenesis type II |