| RS753699011 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder due to PEX1 defect, Peroxisome biogenesis disorder 1B |
| RS753700157 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753700179 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS753701495 |
HYDIN
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia 5, Primary ciliary dyskinesia 5 |
| RS753701569 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS753701755 |
VWF
|
Health Risk |
Pathogenic |
von Willebrand disease type 3, von Willebrand disease type 3 |
| RS753702133 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac anomalies - developmental delay - facial dysmorphism syndrome, Dextro-looped transposition of the great arteries |
| RS753703762 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, VPS13B-related disorder |
| RS753703868 |
ST3GAL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS753705135 |
COL7A1
|
Health Risk |
Likely pathogenic |
— |
| RS753705888 |
RBM28
|
Health Risk |
Likely pathogenic |
ANE syndrome, ANE syndrome |
| RS753706965 |
PCK2;NRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Phosphoenolpyruvate carboxykinase deficiency, mitochondrial |
| RS753707154 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS753707182 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS753707206 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS753707755 |
ZMIZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753708048 |
CYP7B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia 5A |
| RS753709131 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Breast-ovarian cancer |
| RS753709490 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753709519 |
SLC19A1;COL18A1
|
Health Risk |
Likely pathogenic |
— |
| RS753711137 |
PSMB10
|
Health Risk |
Pathogenic |
Proteasome-associated autoinflammatory syndrome 5, Proteasome-associated autoinflammatory syndrome 5 |
| RS753711190 |
LAMB3
|
Health Risk |
Pathogenic |
Junctional epidermolysis bullosa gravis of Herlitz, Amelogenesis imperfecta type 1A |
| RS753711253 |
ACAD9
|
Health Risk |
Pathogenic/Likely pathogenic |
Acyl-CoA dehydrogenase 9 deficiency, Mitochondrial complex I deficiency |
| RS753711667 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS753712072 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Inborn genetic diseases |
| RS753712951 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Inborn genetic diseases |
| RS753712960 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS753713015 |
NUS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of glycosylation, type IAA |
| RS753713629 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS753713810 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS753714506 |
CTNNA1
|
Health Risk |
Pathogenic |
— |
| RS753714824 |
LSS
|
Health Risk |
Pathogenic |
— |
| RS753716627 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS753718572 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS753719501 |
TUBA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Lissencephaly due to TUBA1A mutation, Tubulinopathy |
| RS753719949 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome |
| RS753720421 |
MDFIC
|
Health Risk |
Pathogenic |
Lymphatic malformation 12, Lymphatic malformation 12 |
| RS753720576 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS753721331 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast and/or ovarian cancer |
| RS753721437 |
OCA2
|
Health Risk |
Likely pathogenic |
Oculocutaneous albinism, Oculocutaneous albinism |
| RS753723223 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS753723230 |
RECQL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS753723351 |
SLC2A10
|
Health Risk |
Likely pathogenic |
Arterial tortuosity syndrome, Arterial tortuosity syndrome |
| RS753723769 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS753724503 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS753725579 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperkalemic periodic paralysis, Hyperkalemic periodic paralysis |
| RS753726014 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Inborn genetic diseases |
| RS753727461 |
FANCG
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group G, Fanconi anemia |
| RS753728435 |
FANCA
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia complementation group A |
| RS753729414 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS753729438 |
LPIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Majeed syndrome, Autoinflammatory syndrome |
| RS753730009 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS753730553 |
ARMC9
|
Health Risk |
Likely pathogenic |
— |
| RS753731408 |
CHRNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS753731849 |
CBS
|
Health Risk |
Conflicting classifications of pathogenicity |
HYPERHOMOCYSTEINEMIA, THROMBOTIC |
| RS753732275 |
SLC24A5
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS753732321 |
CLN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis 5 |
| RS753732362 |
RAB27A
|
Health Risk |
Conflicting classifications of pathogenicity |
Griscelli syndrome type 2, Autoinflammatory syndrome |
| RS753732596 |
DARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome, Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome |
| RS753733095 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Senior-Loken syndrome 4 |
| RS753733164 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 2, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS753733901 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS753734433 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS753734546 |
NR0B1
|
Health Risk |
Pathogenic |
Congenital adrenal hypoplasia, X-linked |
| RS753734834 |
ASH1L
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 52 |
| RS753735306 |
KIR3DL3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753737612 |
SIM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Obesity due to SIM1 deficiency, SIM1-related disorder |
| RS753739238 |
SON
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753739358 |
LHFPL5
|
Health Risk |
Pathogenic/Likely pathogenic |
Deafness, Deafness |
| RS753739746 |
MSR1
|
Health Risk |
Likely pathogenic |
Ovarian cancer, Ovarian cancer |
| RS753740913 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS753741123 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS753742613 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 1 |
| RS753743263 |
AMT
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS753743625 |
HERC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental delay with autism spectrum disorder and gait instability, Inborn genetic diseases |
| RS753744335 |
NOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Regional enteritis |
| RS753745170 |
SLC1A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753746099 |
FREM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Isolated cryptophthalmia, Fraser syndrome 2 |
| RS753746307 |
GAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Giant axonal neuropathy 1, Giant axonal neuropathy 1 |
| RS753747037 |
EGR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, type I |
| RS753747243 |
TFR2
|
Health Risk |
Pathogenic |
Hereditary hemochromatosis, Hereditary hemochromatosis |
| RS753747821 |
IMPG2
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 56, Retinal dystrophy |
| RS753748759 |
WNT9B
|
Health Risk |
Likely pathogenic |
Cystic renal dysplasia, Chronic kidney disease |
| RS753749502 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS753749828 |
SAMD9L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753750358 |
FANCI
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS753751183 |
CPS1
|
Health Risk |
Likely pathogenic |
Congenital hyperammonemia, type I |
| RS753751194 |
SYN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Epilepsy |
| RS753751373 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS753752321 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS753753954 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Congenital contractural arachnodactyly |
| RS753754773 |
CD36
|
Health Risk |
Pathogenic/Likely pathogenic |
CD36-related disorder, Platelet-type bleeding disorder 10 |
| RS753756119 |
PRMT7
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature-brachydactyly-obesity-global developmental delay syndrome, Short stature-brachydactyly-obesity-global developmental delay syndrome |
| RS753756949 |
FASN
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS753757610 |
KCNJ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Andersen Tawil syndrome, Short QT syndrome type 3 |
| RS753757778 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS753758073 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS753758429 |
ACADS
|
Health Risk |
Likely pathogenic |
— |
| RS753758872 |
PNPLA8
|
Health Risk |
Pathogenic |
Mitochondrial myopathy-lactic acidosis-deafness syndrome, Mitochondrial myopathy-lactic acidosis-deafness syndrome |
| RS753759302 |
CLCN7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |