| RS753596034 |
GNPTG
|
Health Risk |
Pathogenic |
GNPTG-mucolipidosis, GNPTG-mucolipidosis |
| RS753596204 |
ANKLE2
|
Health Risk |
Pathogenic |
Microcephaly 16, primary |
| RS753596825 |
WDR19
|
Health Risk |
Conflicting classifications of pathogenicity |
Cranioectodermal dysplasia 4, Asphyxiating thoracic dystrophy 5 |
| RS753597039 |
MCPH1
|
Health Risk |
Pathogenic |
Microcephaly 1, primary |
| RS753598091 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753598147 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS753598640 |
ARHGEF18
|
Health Risk |
Pathogenic |
— |
| RS753599044 |
POC1B
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 20, Cone-rod dystrophy 20 |
| RS753599265 |
FBN3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753599401 |
IFIH1
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 7, Aicardi-Goutieres syndrome 7 |
| RS753599581 |
COL10A1
|
Health Risk |
Conflicting classifications of pathogenicity |
COL10A1-related disorder, Metaphyseal chondrodysplasia |
| RS753599820 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Porokeratosis 3, disseminated superficial actinic type |
| RS753600208 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753600344 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Thyroid dyshormonogenesis 6, Inborn genetic diseases |
| RS753602333 |
ODAD2
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 23, Primary ciliary dyskinesia 23 |
| RS753602520 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753603040 |
NT5C2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 45, Hereditary spastic paraplegia |
| RS753603407 |
SLC40A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hemochromatosis type 4, SLC40A1-related disorder |
| RS753603433 |
PROS1
|
Health Risk |
Likely pathogenic |
Thrombophilia due to protein S deficiency, autosomal dominant |
| RS753603959 |
JMJD1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Early myoclonic encephalopathy, Early myoclonic encephalopathy |
| RS753604828 |
BBS10
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome |
| RS753605564 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS753607290 |
NPHP1
|
Health Risk |
Likely pathogenic |
— |
| RS753608267 |
SLC5A5
|
Health Risk |
Pathogenic |
— |
| RS753609023 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS753609161 |
TSFM
|
Health Risk |
Likely pathogenic |
Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3, Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3 |
| RS753609310 |
RHO
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS753610150 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS753611080 |
ZMYM2
|
Health Risk |
Likely pathogenic |
Neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities, Congenital anomaly of kidney and urinary tract |
| RS753611141 |
PMPCA
|
Health Risk |
Pathogenic |
13 conditions, Autosomal recessive spinocerebellar ataxia 2 |
| RS753611165 |
VAPB
|
Health Risk |
Conflicting classifications of pathogenicity |
Adult-onset proximal spinal muscular atrophy, autosomal dominant |
| RS753611182 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS753614067 |
BEST1;FTH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive bestrophinopathy, Retinal dystrophy |
| RS753614306 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS753614861 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS753615126 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS753616848 |
NPHP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis 3 |
| RS753616960 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Nemaline myopathy 6 |
| RS753617680 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS753618006 |
PLCG2
|
Health Risk |
Likely pathogenic |
Familial cold autoinflammatory syndrome 3, Familial cold autoinflammatory syndrome 3 |
| RS753618520 |
DTNBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753618932 |
ABCC8
|
Health Risk |
Likely pathogenic |
Neonatal diabetes mellitus, Neonatal diabetes mellitus |
| RS753619551 |
PCARE
|
Health Risk |
Pathogenic |
Retinal dystrophy, Autosomal recessive retinitis pigmentosa |
| RS753620447 |
RECQL4
|
Health Risk |
Pathogenic |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS753620726 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS753621591 |
SPINK5
|
Health Risk |
Pathogenic |
Netherton syndrome, Ichthyosis linearis circumflexa |
| RS753623518 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, autosomal dominant |
| RS753623939 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Singleton-Merten syndrome 1, Aicardi-Goutieres syndrome 7 |
| RS753624268 |
INSR
|
Health Risk |
Conflicting classifications of pathogenicity |
Insulin-resistant diabetes mellitus AND acanthosis nigricans, Rabson-Mendenhall syndrome |
| RS753625117 |
CNGA3
|
Health Risk |
Pathogenic/Likely pathogenic |
Achromatopsia 2, Achromatopsia 2 |
| RS753627056 |
CTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Dyskeratosis congenita |
| RS753627633 |
TP63
|
Health Risk |
Conflicting classifications of pathogenicity |
Orofacial cleft 8, TP63-Related Spectrum Disorders |
| RS753627675 |
TTC21B
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal dysplasia and retinal aplasia, Asphyxiating thoracic dystrophy 4 |
| RS753627680 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS753628301 |
LTBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani syndrome, Glaucoma 3 |
| RS753630034 |
PTEN
|
Health Risk |
Likely pathogenic |
PTEN hamartoma tumor syndrome, Hereditary cancer-predisposing syndrome |
| RS753630324 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS753631084 |
HNF1B
|
Health Risk |
Uncertain risk allele |
Maturity-onset diabetes of the young, Maturity-onset diabetes of the young |
| RS753631154 |
ALG8
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG8 congenital disorder of glycosylation, ALG8 congenital disorder of glycosylation |
| RS753631615 |
TRAPPC11
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type R18, Autosomal recessive limb-girdle muscular dystrophy type R18 |
| RS753632453 |
PMM2
|
Health Risk |
Pathogenic |
PMM2-congenital disorder of glycosylation, PMM2-congenital disorder of glycosylation |
| RS753632833 |
COL7A1
|
Health Risk |
Likely pathogenic |
— |
| RS753634502 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS753634759 |
MAFB
|
Health Risk |
Conflicting classifications of pathogenicity |
Multicentric carpo-tarsal osteolysis with or without nephropathy, Multicentric carpo-tarsal osteolysis with or without nephropathy |
| RS753634998 |
EPHB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS753635972 |
MTHFS
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with microcephaly, epilepsy |
| RS753636068 |
CASQ2
|
Health Risk |
Pathogenic/Likely pathogenic |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 2 |
| RS753636102 |
IMPG1
|
Health Risk |
Pathogenic |
— |
| RS753637056 |
NPC1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type C1 |
| RS753638532 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tumor predisposition syndrome 3 |
| RS753638647 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS753638837 |
UPB1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753638942 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease due to ABCA3 deficiency, Interstitial lung disease due to ABCA3 deficiency |
| RS753639475 |
SHPK
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753639706 |
IGHMBP2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2S, Charcot-Marie-Tooth disease axonal type 2S |
| RS753640735 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS753640924 |
TWNK
|
Health Risk |
Conflicting classifications of pathogenicity |
Perrault syndrome 5, Perrault syndrome 5 |
| RS753641201 |
TRAPPC9
|
Health Risk |
Pathogenic |
— |
| RS753641926 |
ERCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group D |
| RS753642146 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753643550 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS753643819 |
GDF1
|
Health Risk |
Pathogenic |
Right atrial isomerism, Right atrial isomerism |
| RS753644648 |
NPR2
|
Health Risk |
Likely pathogenic |
Acromesomelic dysplasia 1, Maroteaux type |
| RS753645186 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Uterine corpus endometrial carcinoma |
| RS753645200 |
TNNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 2, Cardiomyopathy |
| RS753645263 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 5 |
| RS753645306 |
VPS13B
|
Health Risk |
Pathogenic |
Cohen syndrome, Cohen syndrome |
| RS753645971 |
GATA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness-lymphedema-leukemia syndrome, Monocytopenia with susceptibility to infections |
| RS753646712 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS753646931 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS753647133 |
SALL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Duane-radial ray syndrome, Duane-radial ray syndrome |
| RS753647278 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS753648048 |
DONSON
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS753648112 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease due to ABCA3 deficiency, Hereditary pulmonary alveolar proteinosis |
| RS753648691 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS753648991 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS753649082 |
KIAA0586
|
Health Risk |
Likely pathogenic |
Short-rib thoracic dysplasia 14 with polydactyly, Joubert syndrome 23 |
| RS753649097 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753649614 |
DNAAF4
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 25, Dyslexia |
| RS753650233 |
SPG11
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia 11 |