| RS764156722 |
CHEK2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS764157190 |
SPTA1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS764158113 |
UBR1
|
Health Risk |
Pathogenic |
— |
| RS764158202 |
TRAPPC11
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type R18, Autosomal recessive limb-girdle muscular dystrophy type R18 |
| RS764159237 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebrooculofacioskeletal syndrome 1, Age related macular degeneration 5 |
| RS764159372 |
FASN
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, FASN-related disorder |
| RS764159927 |
OTOG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764160079 |
RPE65
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 2, Leber congenital amaurosis 2 |
| RS764160271 |
TGFBR2
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Familial thoracic aortic aneurysm and aortic dissection, Malignant tumor of esophagus |
| RS764160345 |
AIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS764160563 |
AGRN
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome, Congenital myasthenic syndrome 8 |
| RS764160782 |
CBS
|
Health Risk |
Pathogenic/Likely pathogenic |
Classic homocystinuria, Homocystinuria |
| RS764162255 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive spastic paraplegia type 78, Kufor-Rakeb syndrome |
| RS764162597 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Hypertrophic cardiomyopathy 6 |
| RS764162842 |
PCDH15
|
Health Risk |
Likely pathogenic |
Usher syndrome type 1D, Usher syndrome type 1D |
| RS764163418 |
EYS
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 25 |
| RS764163895 |
IL12B
|
Health Risk |
Conflicting classifications of pathogenicity |
Mendelian susceptibility to mycobacterial diseases due to complete IL12B deficiency, IL12B-related disorder |
| RS764164178 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS764164384 |
BBS2
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome 2, Bardet-Biedl syndrome |
| RS764164607 |
ETFDH
|
Health Risk |
Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS764164808 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764164884 |
FYCO1
|
Health Risk |
Pathogenic/Likely pathogenic |
Abnormality of the eye, Cataract 18 |
| RS764166022 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia |
| RS764167122 |
BPTF
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, BPTF-related disorder |
| RS764168088 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764168489 |
CTNS
|
Health Risk |
Likely pathogenic |
Ocular cystinosis, Juvenile nephropathic cystinosis |
| RS764168526 |
CTSK
|
Health Risk |
Pathogenic |
Pyknodysostosis, Pyknodysostosis |
| RS764168768 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS764171223 |
IMPG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS764171255 |
PIEZO2
|
Health Risk |
Likely pathogenic |
Arthrogryposis, distal |
| RS764171734 |
PMS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS764171953 |
NTRK1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS764173488 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic acidemia |
| RS764174111 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS764174354 |
TECRL
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS764174474 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Migraine, familial hemiplegic |
| RS764177808 |
TMPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Loeys-Dietz syndrome 2, Loeys-Dietz syndrome 2 |
| RS764177838 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS764177904 |
LAMA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa gravis of Herlitz, Laryngo-onycho-cutaneous syndrome |
| RS764178205 |
CCDC88C
|
Health Risk |
Pathogenic |
— |
| RS764178233 |
OTOGL
|
Health Risk |
Pathogenic |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 84B |
| RS764178736 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Transitory neonatal diabetes mellitus, Maturity-onset diabetes of the young |
| RS764179161 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS764179800 |
MMADHC
|
Health Risk |
Likely pathogenic |
Methylmalonic aciduria and homocystinuria type cblD, Methylmalonic aciduria and homocystinuria type cblD |
| RS764179880 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS764180060 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS764180110 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS764180204 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS764180413 |
COG5
|
Health Risk |
Conflicting classifications of pathogenicity |
COG5-congenital disorder of glycosylation, COG5-congenital disorder of glycosylation |
| RS764180850 |
SOX10
|
Health Risk |
Conflicting classifications of pathogenicity |
SOX10-related disorder, SOX10-related disorder |
| RS764181464 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS764182382 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS764182496 |
FLG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764182550 |
OTOA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764182950 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS764185466 |
AQP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Diabetes insipidus, nephrogenic |
| RS764185528 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS764185628 |
SUCLG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 9, Mitochondrial DNA depletion syndrome 9 |
| RS764186025 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS764186203 |
SPG11
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS764186411 |
FANCL
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group L, Fanconi anemia complementation group L |
| RS764186905 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS764188161 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS764188556 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS764189309 |
RPE65
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 20, Leber congenital amaurosis 2 |
| RS764189338 |
MTTP
|
Health Risk |
Pathogenic |
Abetalipoproteinaemia, Abetalipoproteinaemia |
| RS764189353 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency |
| RS764189408 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS764189883 |
ZSWIM7
|
Health Risk |
Likely pathogenic |
Infertility disorder, Infertility disorder |
| RS764189986 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Myopathy |
| RS764190606 |
LOX
|
Health Risk |
Pathogenic |
— |
| RS764190942 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS764191178 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS764191883 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS764192020 |
GLB1
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-B |
| RS764193290 |
COL6A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Dystonia 27, Bethlem myopathy 1A |
| RS764194945 |
CASK
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, CASK-related |
| RS764195249 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS764195998 |
SETD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Luscan-Lumish syndrome, Inborn genetic diseases |
| RS764196019 |
XDH
|
Health Risk |
Likely pathogenic |
Xanthinuria type II, Xanthinuria type II |
| RS764196059 |
HNF4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 1, Type 2 diabetes mellitus |
| RS764196171 |
IDUA
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 1, Hurler syndrome |
| RS764196309 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS764196357 |
PHGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
PHGDH deficiency, PHGDH deficiency |
| RS764196809 |
UNC13D
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Autoinflammatory syndrome |
| RS764197422 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
DiGeorge syndrome, Cardiovascular phenotype |
| RS764199611 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS764200669 |
GRIA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764201055 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 9, Atypical hemolytic-uremic syndrome with C3 anomaly |
| RS764201220 |
WDR62
|
Health Risk |
Pathogenic |
Microcephaly 2, primary |
| RS764201887 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS764201905 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS764203302 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS764203580 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS76420383 |
OTOGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764205432 |
SATB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Chromosome 2q32-q33 deletion syndrome, Inborn genetic diseases |
| RS764207146 |
DDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of aromatic-L-amino-acid decarboxylase, Inborn genetic diseases |
| RS76420733 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 2 |
| RS764207947 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Autoinflammatory syndrome |
| RS764208388 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |