| RS764326184 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS764326593 |
AP4M1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 50, Hereditary spastic paraplegia 50 |
| RS764327751 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS764330337 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS764332870 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 48, Inborn genetic diseases |
| RS764333096 |
NFIB
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, Macrocephaly |
| RS764333715 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, Inborn genetic diseases |
| RS764333790 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Early-onset myopathy with fatal cardiomyopathy |
| RS764334802 |
ABCG8
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Sitosterolemia 1 |
| RS764334983 |
PKD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant polycystic kidney disease, Polycystic kidney disease 2 |
| RS764335447 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, Hajdu-Cheney syndrome |
| RS764337568 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764337688 |
TDRD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cataract 36, Cataract 36 |
| RS764337753 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS764338697 |
MTHFR
|
Health Risk |
Pathogenic/Likely pathogenic |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, See cases |
| RS764338863 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS764339075 |
EXOSC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontocerebellar hypoplasia, type 1C |
| RS764340351 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 2 with or without anosmia, Pfeiffer syndrome |
| RS764341143 |
KMT2E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764342199 |
PMS2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS764342492 |
CDK5RAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 3, primary |
| RS764342695 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
BENTA disease, Severe combined immunodeficiency due to CARD11 deficiency |
| RS764343290 |
FOXG1
|
Health Risk |
Pathogenic |
FOXG1 disorder, FOXG1 disorder |
| RS764343937 |
HEXA
|
Health Risk |
Pathogenic/Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS764344701 |
SECISBP2
|
Health Risk |
Likely pathogenic |
— |
| RS764346452 |
PEX7
|
Health Risk |
Pathogenic/Likely pathogenic |
Rhizomelic chondrodysplasia punctata type 1, Peroxisome biogenesis disorder 9B |
| RS76434661 |
GJB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Hearing impairment |
| RS764346736 |
LAMB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Pierson syndrome |
| RS764346876 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 5, primary |
| RS764347085 |
ICOSLG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764347583 |
MMUT
|
Health Risk |
Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency |
| RS764348039 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS764349043 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS764349883 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS764352879 |
ASXL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764353299 |
COL7A1
|
Health Risk |
Pathogenic/Likely pathogenic |
7 conditions, 7 conditions |
| RS764353860 |
PMM2
|
Health Risk |
Pathogenic/Likely pathogenic |
PMM2-congenital disorder of glycosylation, Inborn genetic diseases |
| RS764354581 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, Familial cold autoinflammatory syndrome 2 |
| RS764354954 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS764355087 |
ABCA12
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 4B, Autosomal recessive congenital ichthyosis 4B |
| RS764355476 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS764355552 |
COL1A2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, classic type |
| RS764356037 |
ASL
|
Health Risk |
Pathogenic/Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS764356283 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Polycystic kidney disease |
| RS764356392 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, normal intelligence and immunodeficiency |
| RS764356904 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS764357395 |
AGA
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Aspartylglucosaminuria |
| RS764358108 |
VHL
|
Health Risk |
Conflicting classifications of pathogenicity |
Von Hippel-Lindau syndrome, Von Hippel-Lindau syndrome |
| RS764358419 |
CHMP1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764358542 |
PRKDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to DNA-PKcs deficiency, Severe combined immunodeficiency due to DNA-PKcs deficiency |
| RS764359340 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS764360108 |
USH1C
|
Health Risk |
Pathogenic |
— |
| RS764360302 |
FARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 14, Inborn genetic diseases |
| RS764362150 |
TULP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764362221 |
EYS
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 25, Retinitis pigmentosa 25 |
| RS764362617 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Familial isolated arrhythmogenic right ventricular dysplasia |
| RS764363274 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Myopathy |
| RS764363798 |
ZFYVE26
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 15, Spastic paraplegia |
| RS764363889 |
MYH13
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764364345 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS764364492 |
MANBA
|
Health Risk |
Pathogenic/Likely pathogenic |
Beta-D-mannosidosis, Beta-D-mannosidosis |
| RS764364981 |
GFM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764365066 |
GABBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Inborn genetic diseases |
| RS764365348 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764366547 |
APOA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS764367185 |
ADGRG1
|
Health Risk |
Pathogenic |
Bilateral frontoparietal polymicrogyria, Bilateral frontoparietal polymicrogyria |
| RS764367878 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS76436818 |
RNASEH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 4, Aicardi Goutieres syndrome |
| RS764368214 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS764368218 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS764368324 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
FLNB-Related Spectrum Disorders, FLNB-Related Spectrum Disorders |
| RS764369378 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to CARD11 deficiency, BENTA disease |
| RS764370512 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS764371254 |
MYO5A
|
Health Risk |
Pathogenic |
Griscelli syndrome type 1, Griscelli syndrome type 1 |
| RS764374133 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS764374251 |
MFN2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS764374356 |
CARMIL2
|
Health Risk |
Pathogenic |
— |
| RS764374591 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764374746 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia 7 |
| RS764374927 |
CHRND
|
Health Risk |
Pathogenic |
Lethal multiple pterygium syndrome, Lethal multiple pterygium syndrome |
| RS764375446 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS764376138 |
COL4A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hematuria, benign familial |
| RS764376151 |
VPS13A
|
Health Risk |
Pathogenic/Likely pathogenic |
VPS13A-related disorder, Chorea-acanthocytosis |
| RS764376758 |
MAN2B1
|
Health Risk |
Pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS764377335 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS764377394 |
PGM3
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency disease, Immunodeficiency 23 |
| RS764379119 |
EXT2
|
Health Risk |
Pathogenic |
Exostoses, multiple |
| RS764379398 |
TJP2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS764379478 |
CUBN
|
Health Risk |
Likely pathogenic |
— |
| RS764379536 |
PNKP
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS764379691 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS764380346 |
IFIH1
|
Health Risk |
Likely pathogenic |
Immunodeficiency 95, Immunodeficiency 95 |
| RS764380594 |
AQP2
|
Health Risk |
Pathogenic |
Nephrogenic diabetes insipidus, Nephrogenic diabetes insipidus |
| RS764380675 |
TMEM67
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS764381074 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, COL1A1-related disorder |
| RS764381126 |
ADAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Symmetrical dyschromatosis of extremities, Aicardi-Goutieres syndrome 6 |
| RS764381446 |
DNAI2
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764381544 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS764382519 |
DNAJC21
|
Health Risk |
Pathogenic |
— |
| RS764382536 |
MKKS
|
Health Risk |
Pathogenic |
McKusick-Kaufman syndrome, McKusick-Kaufman syndrome |