| RS764263034 |
LYZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial visceral amyloidosis, Ostertag type |
| RS764263517 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Myopathy |
| RS764264135 |
H3C1
|
Health Risk |
Likely pathogenic |
Multiple myeloma, Multiple myeloma |
| RS764264434 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764264834 |
HMGCL
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Deficiency of hydroxymethylglutaryl-CoA lyase |
| RS764265933 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS764266244 |
POMGNT1
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2O, Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability) |
| RS764266722 |
CHRNG
|
Health Risk |
Pathogenic/Likely pathogenic |
Lethal multiple pterygium syndrome, Autosomal recessive multiple pterygium syndrome |
| RS764268036 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS764268346 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS764271022 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS764272139 |
SLC12A6
|
Health Risk |
Conflicting classifications of pathogenicity |
Agenesis of the corpus callosum with peripheral neuropathy, Inborn genetic diseases |
| RS764273304 |
ARG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Arginase deficiency, Arginase deficiency |
| RS764273631 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS764274149 |
HOGA1
|
Health Risk |
Pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS764274816 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Acute febrile neutrophilic dermatosis |
| RS764275222 |
CNTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial adult myoclonic |
| RS764275775 |
TYMP
|
Health Risk |
Pathogenic |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS764275810 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Saldino-Mainzer syndrome |
| RS764276907 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS764276946 |
NDUFS8
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Leigh syndrome |
| RS764278381 |
CEP89
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764278567 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS764279057 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS764279608 |
MYO18B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764279982 |
GARNL3
|
Health Risk |
Likely pathogenic |
Intellectual disability, Intellectual disability |
| RS764280787 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Severe combined immunodeficiency due to CARD11 deficiency |
| RS764281068 |
PPP1R12A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764282256 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marshall syndrome, Stickler syndrome type 2 |
| RS764284379 |
ETFDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS764286389 |
MCCC2
|
Health Risk |
Pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, 3-methylcrotonyl-CoA carboxylase 2 deficiency |
| RS764286950 |
PLA2G6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Parkinson disease 14, Autosomal recessive Parkinson disease 14 |
| RS764287278 |
LRPPRC
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS764287987 |
POLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive sclerosing poliodystrophy, POLG-related disorder |
| RS764288193 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764288902 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
8 conditions, 8 conditions |
| RS764289504 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS764289801 |
DAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2P, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS764290037 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS764290273 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer, EGFR-related lung cancer |
| RS764290955 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital multicore myopathy with external ophthalmoplegia, Central core myopathy |
| RS764291252 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS764291274 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS764292673 |
FBP1
|
Health Risk |
Pathogenic |
Fructose-biphosphatase deficiency, Fructose-biphosphatase deficiency |
| RS764292783 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Inborn genetic diseases |
| RS764292893 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile liver failure syndrome 2, Short stature-optic atrophy-Pelger-Huët anomaly syndrome |
| RS764296185 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS764296457 |
HPS5
|
Health Risk |
Likely pathogenic |
Hermansky-Pudlak syndrome 5, Hermansky-Pudlak syndrome 5 |
| RS764296800 |
ABCB11
|
Health Risk |
Likely pathogenic |
Cholestasis, intrahepatic |
| RS764296921 |
WDR19
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 5, Senior-Loken syndrome 8 |
| RS764297134 |
HSPB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2F, Charcot-Marie-Tooth disease axonal type 2F |
| RS764298283 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 8 |
| RS764298491 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary breast ovarian cancer syndrome |
| RS764299277 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, type 4 |
| RS764300456 |
HSD17B4
|
Health Risk |
Conflicting classifications of pathogenicity |
Bifunctional peroxisomal enzyme deficiency, Perrault syndrome |
| RS764301648 |
RASGRP2
|
Health Risk |
Pathogenic |
— |
| RS764301963 |
DENND5A
|
Health Risk |
Likely pathogenic |
— |
| RS764301997 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant cerebellar ataxia, Autosomal dominant cerebellar ataxia |
| RS764303128 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS764303339 |
SLC12A3
|
Health Risk |
Pathogenic |
— |
| RS764304126 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS764305237 |
HMBS
|
Health Risk |
Likely pathogenic |
— |
| RS764305873 |
COL27A1
|
Health Risk |
Pathogenic |
— |
| RS764306023 |
FANCI
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group I, Fanconi anemia complementation group I |
| RS764306025 |
KCNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 26 |
| RS764306633 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 4 |
| RS764307090 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764308612 |
PIP5K1C
|
Health Risk |
Pathogenic |
— |
| RS764308870 |
POU4F3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 15, Autosomal dominant nonsyndromic hearing loss 15 |
| RS764308981 |
SLC26A5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764309755 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS764310195 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS764311076 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS764311778 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS764311787 |
MOCS2
|
Health Risk |
Pathogenic |
— |
| RS764312409 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS764312466 |
EGF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764313717 |
PYGM
|
Health Risk |
Pathogenic/Likely pathogenic |
McArdle disease, mild |
| RS764313785 |
POLR3A
|
Health Risk |
Likely pathogenic |
Leukodystrophy, hypomyelinating |
| RS764314231 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS764314276 |
TCOF1
|
Health Risk |
Likely pathogenic |
Treacher Collins syndrome 1, Treacher Collins syndrome 1 |
| RS764314608 |
NCF2
|
Health Risk |
Pathogenic |
Granulomatous disease, chronic |
| RS764314612 |
AGT
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal tubular dysgenesis of genetic origin, Renal tubular dysgenesis of genetic origin |
| RS764315978 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Dilated cardiomyopathy 1AA |
| RS764316153 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS764316702 |
PCCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Propionic acidemia, Inborn genetic diseases |
| RS764317955 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS764317969 |
SMPD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Niemann-Pick disease, type A |
| RS764318570 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease |
| RS764319566 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764320060 |
GPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Simpson-Golabi-Behmel syndrome type 1 |
| RS764320767 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 4, Left ventricular noncompaction 10 |
| RS764321075 |
APRT
|
Health Risk |
Pathogenic |
Adenine phosphoribosyltransferase deficiency, Adenine phosphoribosyltransferase deficiency |
| RS764321665 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS764322456 |
MITF
|
Health Risk |
Conflicting classifications of pathogenicity |
Tietz syndrome, Waardenburg syndrome type 2A |
| RS764322898 |
ALPL
|
Health Risk |
Likely pathogenic |
Infantile hypophosphatasia, ALPL-related disorder |
| RS764323391 |
TRAPPC12
|
Health Risk |
Pathogenic |
Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome, Early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome |
| RS764323652 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Autosomal dominant Alport syndrome |
| RS764324827 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS764325655 |
SERPINA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Alpha-1-antitrypsin deficiency, PI NULL(BOLTON) |