| RS764095900 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS764096773 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS764097337 |
CYLD
|
Health Risk |
Conflicting classifications of pathogenicity |
Brooke-Spiegler syndrome, Familial multiple trichoepitheliomata |
| RS764097983 |
TMEM67
|
Health Risk |
Pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS764100025 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS764100439 |
AP3B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 2, Hermansky-Pudlak syndrome 2 |
| RS764100516 |
CHSY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Temtamy preaxial brachydactyly syndrome, Temtamy preaxial brachydactyly syndrome |
| RS764101138 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764103060 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS764103256 |
DMRT3
|
Health Risk |
Likely pathogenic |
Premature ovarian failure, Premature ovarian failure |
| RS76410435 |
TTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyloidosis, hereditary systemic 1 |
| RS764105296 |
ALOX12B
|
Health Risk |
Likely pathogenic |
— |
| RS764106639 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS764107333 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Permanent neonatal diabetes mellitus, Diabetes mellitus |
| RS764107355 |
HAMP
|
Health Risk |
Likely pathogenic |
— |
| RS764108297 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS76410834 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS764109067 |
ARL13B
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome and related disorders, Joubert syndrome 8 |
| RS764109533 |
IMPG2
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 56 |
| RS764110569 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS764111837 |
IGHMBP2
|
Health Risk |
Likely pathogenic |
Autosomal recessive distal spinal muscular atrophy 1, Charcot-Marie-Tooth disease axonal type 2S |
| RS764111950 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, 11p partial monosomy syndrome |
| RS764112241 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome |
| RS764113446 |
USH2A
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS764113584 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS764113705 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS764115258 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cognitive impairment with or without cerebellar ataxia, Seizures |
| RS764118184 |
KIAA0586
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 23, Short-rib thoracic dysplasia 14 with polydactyly |
| RS764118613 |
RAD21
|
Health Risk |
Likely pathogenic |
Cornelia de Lange syndrome 4, Cornelia de Lange syndrome 4 |
| RS764119686 |
DMD
|
Health Risk |
Likely pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS764119764 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764120517 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS764121005 |
EFTUD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mandibulofacial dysostosis-microcephaly syndrome, Inborn genetic diseases |
| RS764121307 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS764121311 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS764121323 |
NEU1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764122274 |
GDF5
|
Health Risk |
Pathogenic/Likely pathogenic |
9 conditions, 9 conditions |
| RS764122619 |
RAD50
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS764122657 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS764123241 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS764123669 |
NADSYN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Vertebral, cardiac |
| RS764124390 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS764124442 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 4 |
| RS764125009 |
FKTN
|
Health Risk |
Likely pathogenic |
Walker-Warburg congenital muscular dystrophy, Muscular dystrophy-dystroglycanopathy (congenital without intellectual disability) |
| RS764125338 |
TNFRSF13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS764125510 |
ABCB11
|
Health Risk |
Pathogenic |
Familial intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS764126853 |
AR
|
Health Risk |
Pathogenic |
Kennedy disease, Androgen resistance syndrome |
| RS764127291 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Charcot-Marie-Tooth disease axonal type 2O |
| RS764127754 |
GFM2
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation deficiency 39, Combined oxidative phosphorylation deficiency 39 |
| RS764127814 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764127932 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS764128579 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764129741 |
TNNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy 2 |
| RS764130442 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hennekam lymphangiectasia-lymphedema syndrome 2, Van Maldergem syndrome 2 |
| RS764131178 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Inborn genetic diseases |
| RS764132839 |
HNF1B
|
Health Risk |
Uncertain risk allele |
Maturity-onset diabetes of the young, Maturity-onset diabetes of the young |
| RS764132853 |
CSF3R
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive severe congenital neutropenia due to CSF3R deficiency, Autosomal recessive severe congenital neutropenia due to CSF3R deficiency |
| RS764132899 |
RPL15
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764133411 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764133797 |
PHKB
|
Health Risk |
Pathogenic |
PHKB-related disorder, Glycogen storage disease IXb |
| RS764134388 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS764134891 |
NAGLU
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-B |
| RS764137081 |
KIAA1549
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764138752 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, LRP5-related disorder |
| RS764139968 |
ZNF469
|
Health Risk |
Pathogenic/Likely pathogenic |
Brittle cornea syndrome 1, Brittle cornea syndrome 1 |
| RS76414035 |
TPM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arthrogryposis, distal |
| RS764140399 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Tuberous sclerosis 1 |
| RS764140840 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS764141450 |
CYP27B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Vitamin D-dependent rickets, type 1 |
| RS764142151 |
NRL
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS764142194 |
TYMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS764142241 |
ATF6
|
Health Risk |
Likely pathogenic |
Achromatopsia, Achromatopsia |
| RS764143249 |
PKLR
|
Health Risk |
Pathogenic |
— |
| RS764143976 |
KCNJ11
|
Health Risk |
Pathogenic |
— |
| RS764144130 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS764144206 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS764144407 |
FBN1
|
Health Risk |
Pathogenic |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS764146079 |
JAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy, limb-girdle |
| RS764146326 |
TP53
|
Health Risk |
Pathogenic/Likely pathogenic |
Li-Fraumeni syndrome, Li-Fraumeni syndrome 1 |
| RS764146823 |
EDA
|
Health Risk |
Pathogenic |
Hypohidrotic X-linked ectodermal dysplasia, Hypohidrotic X-linked ectodermal dysplasia |
| RS764147237 |
COQ8A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764148793 |
HLCS
|
Health Risk |
Conflicting classifications of pathogenicity |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS764148985 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, NOTCH3-related disorder |
| RS764149433 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS764149816 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glomerulopathy with fibronectin deposits 2, Spondylometaphyseal dysplasia - Sutcliffe type |
| RS764149889 |
IL17RD
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS764150061 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS764150279 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS764150659 |
NAGS
|
Health Risk |
Pathogenic |
Hyperammonemia, type III |
| RS764150912 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS764152134 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS764152659 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Classic or attenuated familial adenomatous polyposis, Familial adenomatous polyposis 1 |
| RS764153192 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS764153521 |
TECTA
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 21, Autosomal recessive nonsyndromic hearing loss 21 |
| RS764154157 |
TYK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 35, Immunodeficiency 35 |
| RS764154647 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
COL11A2-related disorder, COL11A2-related disorder |
| RS764155137 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS764156081 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS764156386 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS764156696 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
VACTERL association, X-linked |