DMRT3 Chromosome 9
Doublesex and mab-3 related transcription factor 3
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What This Gene Does
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in male sex differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including adult walking behavior; regulation of odontogenesis of dentin-containing tooth; and ventral spinal cord interneuron specification. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Associated Conditions (1)
Premature ovarian failure
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS764103256 | Health Risk | Likely pathogenic | Premature ovarian failure, Premature ovarian failure |